584 Results for "

peptide compound

" in MedChemExpress (MCE) Product Catalog:
Products (584)

584 Results for "peptide compound" in MCE Product Catalog:

14
14 Publications Verification
Cat. No.: HY-D0178
CAS No.: 25952-53-8
1-Ethyl-(3-dimethylaminopropyl)carbodiimide hydrochloride is a carbodiimide reagent that can form nucleic acid and compounds with amide bonds. 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride accelerates the formation reaction of esters, amides, and peptides, as a condensing and dehydrating agent, which are often used for polynucleotide synthesis, anhydroxydation, lactonization and esterification .
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7
7 Cited Publications
Cat. No.: HY-101116
CAS No.: 488097-06-9
Purity:  99.67%
Target:  

GCGR

Research Areas:  

Metabolic Disease

GLP-1R Antagonist 1 (compound 5d) is an orally active, CNS penetrant and non-competitive antagonist of glucagon-like peptide 1 receptor (GLP-1R), with an IC50 of 650 nM .
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6
6 Cited Publications
Cat. No.: HY-141539
CAS No.: 2755823-12-0
Purity:  99.93%
Research Areas:  

Cancer

SETDB1-TTD-IN-1 is a SETDB1 methyltransferase activator and SETDB1-TTD competitive inhibitor (Kd of 88 nM), and selectivity for SETDB1-TTD over other tudor and bromodomain proteins. SETDB1-TTD-IN-1 stimulates methyltransferase activity via increased catalytic activity, promotes Akt1 Lys64 methylation, Akt1 Thr308 phosphorylation and activation. SETDB1-TTD-IN-1 prevents SETDB1-TTD-histone H3 peptide association, induces global gene expression changes, exhibits cellular target engagement, and acts as a tool compound for SETDB1-TTD function exploration. SETDB1-TTD-IN-1 can be used for the research of breast cancer .
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2
2 Cited Publications
Cat. No.: HY-112185
CAS No.: 2212020-52-3
Purity:  99.80%
Synonyms: LY3502970; GLP-1 receptor agonist 1
Target:  

GCGR

Orforglipron (LY3502970) (Compound 67) is an orally active agonist for Glucagon-like peptide-1 receptor (GLP-1R), which exhibits potency in ameliorates the type 2 diabete .
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2
2 Cited Publications
Cat. No.: HY-19574
CAS No.: 903895-98-7
Research Areas:  

Inflammation/Immunology

FPR Agonist 43 (compound 43) is a dual formyl peptide receptor 1 (FPR1) and formyl peptide receptor 2 (FPR2)/ALX agonist .
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2
2 Cited Publications
Cat. No.: HY-112862
CAS No.: 301351-95-1
Purity:  ≥98.0%
Research Areas:  

Infection

Arg-AMS (compound 24) is a potent nanomolar inhibitor of arginyl tRNA synthetase, which displays tightly bound inhibitory characteristics for the A-domains in non-ribosomal peptide synthetases (NRPS) enzymes .
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1
1 Cited Publications
Cat. No.: HY-148263
Purity:  ≥98.0%
Target:  

Fluorescent Dye

Research Areas:  

Cancer

Biotin-PEG2000-Thiol is an active compound. Biotin-PEG2000-Thiol is pegylated by binding to streptavidin or antibiotin with high affinity and specificity. Biotin-PEG2000-Thiol can modify biomolecules, proteins, peptides and other small molecule materials. Biotin-PEG2000-Thiol is widely used in the research of agent release and nano new materials .
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1
1 Cited Publications
Cat. No.: HY-150504
CAS No.: 2420551-38-6
Purity:  98.86%
Target:  

Aminopeptidase

Research Areas:  

Inflammation/Immunology

ERAP2-IN-1 (compound 61) is an uncompetitive ERAP2 inhibitor. ERAP2-IN-1 specifically inhibits the ERAP2 peptide hydrolysis activity, inhibiting Arg-AMC hydrolysis with an IC50 of 27 μM and model peptide hydrolysis with an IC50 of 44 μM .
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1
1 Cited Publications
Cat. No.: HY-D0715
CAS No.: 38183-12-9
Synonyms: Ro 20-7234
Fluorescamine is a spirocyclic compound that is non-fluorescent. Fluorescamine reacts rapidly with primary amine groups in proteins under alkaline conditions to generate products with strong fluorescence (Ex/Em: 390/475 nm). Fluorescamine can be used to detect amine-containing compounds, including amino acids, peptides, and proteins .
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1
1 Cited Publications
Cat. No.: HY-NP091
Synonyms: WGA
Wheat Germ Agglutinin (WGA) is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Wheat Germ Agglutinin (WGA) is a biological material or organic compound that can be used in life science research .
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1
1 Cited Publications
Cat. No.: HY-122720
CAS No.: 900308-84-1
Purity:  99.58%
Synonyms: KL-1
Target:  

Apoptosis

Research Areas:  

Cancer

SEC inhibitor KL-1 (KL-1) is a peptide-like lead compound that is an effective selective SEC inhibitor. SEC inhibitor KL-1 promotes apoptosis and has anti-tumor activity. SEC inhibitor KL-1 doses dependently inhibits the AFF4-CCNT1 interaction, with a Ki value of 3.48 μM .
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1
1 Cited Publications
Cat. No.: HY-113283
CAS No.: 451-13-8
Purity:  99.46%
Homogentisic acid is an orally active, blood-brain barrier-permeable amyloidogenic compound that functions as both an amyloid component and a pigment precursor. Accumulation of homogentisic acid downregulates tight junction proteins (such as claudin-5, occludin, ZO-1) and impairs blood-brain barrier integrity. Homogentisic acid and its oxidation product benzoquinone acetic acid not only induce the aggregation and fibrosis of multiple proteins (such as 1-42, α-synuclein, SAA, Transthyretin (TTR), atrial natriuretic peptide), but also trigger oxidative stress, damage to the Wnt/β-catenin pathway, and neurotoxicity, leading to ochronosis pigment deposition and synaptic dysfunction. At specific concentrations, homogentisic acid exerts no cytotoxicity or genotoxicity on human peripheral blood lymphocytes, and even counteracts the genotoxicity induced by Irinotecan (HY-16562). Homogentisic acid serves as an important tool molecule for investigating the mechanisms of diseases including ochronosis, secondary amyloidosis, Alzheimer's disease, and colorectal cancer .
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Cat. No.: HY-172696
DSPE-PEG2000-WYRGRL is a PEG compound which composed of DSPE and a cartilage-targeting peptide (WYRGRL). WYRGRL is a collagen II-targeting peptide that can bind to collagen II α1. DSPE-PEG2000-WYRGRL can be used for drug delivery .
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Cat. No.: HY-156968
CAS No.: 3011682-51-9
Purity:  98.78%
Target:  

GLP Receptor

Research Areas:  

Metabolic Disease

GLP-1 receptor agonist 14 (compound 474) is a potent agonist of glucagon-like peptide-1 (GLP-1). GLP-1 receptor agonist 14 plays an important role in diabetes or other metabolic disorders .
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Cat. No.: HY-D0177
CAS No.: 128625-52-5
Synonyms: Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate
(Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate (Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate) is a peptide coupling reagent and BOP analog. (Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate promotes the reaction of amino and carboxyl groups to form peptide bonds. (Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate can be used in the synthesis of peptide compounds .
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Cat. No.: HY-177203
DSPE-PEG2000-APWHLSSQYSRT is a PEG compound which composed of DSPE and 12-amino acid cardiac targeting peptide (APWHLSSQYSRT). DSPE-PEG2000-APWHLSSQYSRT can be used for drug delivery .
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Cat. No.: HY-W090942
CAS No.: 13171-93-2
Research Areas:  

Others

Z-Gly-Gly-Phe-OH is a substrate for pepsin and thermolysin. Z-Gly-Gly-Phe-OH has an IC50 of 15.8 μM for open sodium channels under pepsin catalysis. Z-Gly-Gly-Phe-OH forms peptide bonds with amine components (such as H-Leu-NHPh) through enzyme-catalyzed condensation reactions, and is active as an intermediate in peptide synthesis .
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Cat. No.: HY-135108
CAS No.: 126088-82-2
Purity:  98.15%
Target:  

Neurokinin Receptor

Research Areas:  

Neurological Disease

QWF Peptide (Compound 4a) is a substance P antagonist with an IC50 of 0.09 μM. QWF Peptide antagonizes the SP-induced contraction of isolated guinea pig trachea strips with an IC50 of 4.7 μM .
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Cat. No.: HY-110269
CAS No.: 1414376-84-3
Purity:  99.91%
Target:  

CXCR

Research Areas:  

Inflammation/Immunology

VUF 11222 (Compound 38) is a CXCR3 non-peptide-like agonist. VUF 11222 can be used in the study of inflammation .
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Cat. No.: HY-W009229
CAS No.: 13726-84-6
Boc-Glu(OtBu)-OH is a protected glutamic acid derivative with two protecting groups: Boc- and OTBu. Boc-Glu(OtBu)-OH can be used in the study of peptide compound synthesis .
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