DSPE-PEG2000-WYRGRL
Based on 1 Customer Validation
DSPE-PEG2000-WYRGRL is a PEG compound which composed of DSPE and a cartilage-targeting peptide (WYRGRL). WYRGRL is a collagen II-targeting peptide that can bind to collagen II α1. DSPE-PEG2000-WYRGRL can be used for drug delivery.
For research use only. We do not sell to patients.
- Purity: 95.0%
- Molecular Weight:2000 (Average)
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Collagen II |
WYRGRL can specifically bind to Collagen II of articular cartilage[1].
WYRGRL exhibits cartilage-targeting activity[2].
The strategy of encapsulating Lecithin (HY-B2235), Cholesterol (HY-N0322), DSPE-PEG2000-WYRGRL, and Urolithin A (HY-100599) into HAMA microspheres using microfluidic and photopolymerization techniques may alleviate cartilage degeneration by targeting chondrocytes and activating mitochondrial autophagy[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Solid
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Molecular Weight 2000 (Average)
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Color White to off-white
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SMILES
[Mal-Cys-WYRGRL]C(CCOCCOC(NCCOP(OC[C@](COC(CCCCCCCCCCCCCCCCC)=O)([H])OC(CCCCCCCCCCCCCCCCC)=O)(O)=O)=O)=O.[n]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : ≥ 100 mg/mL
* "≥" means soluble, but saturation unknown.
Purity & Documentation
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Data Sheet (268 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
[1]. Kai Ren, et al. Zwitterionic polymer modified xanthan gum with collagen II-binding capability for lubrication improvement and ROS scavenging. Carbohydr Polym. 2021 Nov 15:274:118672. [Content Brief]
[2]. Mitsou E, Klein J. Liposome-Based Interventions in Knee Osteoarthritis. Small. 2025 Apr;21(17):e2410060. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DSPE-PEG2000-WYRGRL Related Classifications
HY-172696 Related Classifications
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