2. Metabolic Enzyme/Protease Cytoskeleton
  3. Liposome Collagen
  4. DSPE-PEG2000-WYRGRL

DSPE-PEG2000-WYRGRL is a PEG compound which composed of DSPE and a cartilage-targeting peptide (WYRGRL). WYRGRL is a collagen II-targeting peptide that can bind to collagen II α1. DSPE-PEG2000-WYRGRL can be used for drug delivery.

For research use only. We do not sell to patients.

DSPE-PEG2000-WYRGRL

DSPE-PEG2000-WYRGRL Chemical Structure

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Based on 1 publication(s) in Google Scholar

DSPE-PEG2000-WYRGRL Related Antibodies

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Description

DSPE-PEG2000-WYRGRL is a PEG compound which composed of DSPE and a cartilage-targeting peptide (WYRGRL). WYRGRL is a collagen II-targeting peptide that can bind to collagen II α1. DSPE-PEG2000-WYRGRL can be used for drug delivery[1].

IC50 & Target[1]

Collagen II

 

In Vitro

WYRGRL can specifically bind to Collagen II of articular cartilage[1].
WYRGRL exhibits cartilage-targeting activity[2].
The strategy of encapsulating Lecithin (HY-B2235), Cholesterol (HY-N0322), DSPE-PEG2000-WYRGRL, and Urolithin A (HY-100599) into HAMA microspheres using microfluidic and photopolymerization techniques may alleviate cartilage degeneration by targeting chondrocytes and activating mitochondrial autophagy[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

DSPE-PEG2000-WYRGRL Related Antibodies
Molecular Weight

2000 (Average)

Appearance

Solid

Color

White to off-white

SMILES

[Mal-Cys-WYRGRL]C(CCOCCOC(NCCOP(OC[C@](COC(CCCCCCCCCCCCCCCCC)=O)([H])OC(CCCCCCCCCCCCCCCCC)=O)(O)=O)=O)=O.[n]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL

*"≥" means soluble, but saturation unknown.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
Purity & Documentation
References
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DSPE-PEG2000-WYRGRL Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DSPE-PEG2000-WYRGRLLiposomeCollagenCartilage-targetingInhibitorinhibitorinhibit

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Product Name:
DSPE-PEG2000-WYRGRL
Cat. No.:
HY-172696
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