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permeate

" in MedChemExpress (MCE) Product Catalog:

67

Inhibitors & Agonists

1

Screening Libraries

6

Fluorescent Dye

11

Biochemical Assay Reagents

9

Peptides

1

Inhibitory Antibodies

6

Natural
Products

2

Isotope-Labeled Compounds

1

Click Chemistry

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-114299
    Salcaprozate sodium
    4 Publications Verification

    SNAC

    		 Biochemical Assay Reagents Others
    Salcaprozate sodium (SNAC), an oral absorption promoter, and has the potential as a delivery agent for oral forms of heparin and insulin. Salcaprozate sodium could increase passive transcellular permeation across small intestinal epithelia based on increased lipophilicity arising from non-covalent macromolecule complexation .
    Salcaprozate sodium
  • HY-D1783
    MitoTracker Deep Red FM
    10+ Cited Publications

    MTDR FM

    		 Fluorescent Dye Others
    MitoTracker Deep Red (MTDR) FM fluorescent dye that selectively accumulates in the mitochondrial matrix. MitoTracker Deep Red FM covalently binds mitochondrial proteins by reacting with free mercaptan of cysteine residues, allowing staining of mitochondrial membrane potential independent of membrane potential. Excitation/emission wavelength 644/665 nm . MitoTracker Deep Red dyes have an excitation/emission wavelength of 633/650-750 nm .
    The Ex/Em of MitoTracker Deep Red (MTDR) FM is 644/665 nm.
    MitoTracker Deep Red FM
  • HY-13750
    Ebselen
    20+ Cited Publications

    SPI-1005; PZ-51; CCG-39161

    		 Calcium Channel Virus Protease HIV Phosphatase Infection Neurological Disease Inflammation/Immunology Cancer
    Ebselen (SPI-1005), a glutathione peroxidase mimetic, is a potent voltage-dependent calcium channel (VDCC) blocker . Ebselen potently inhibits M pro (IC50=0.67 μM) and COVID-19 virus (EC50=4.67 μM) .Ebselen is an inhibitor of HIV-1 capsid CTD dimerization. Ebselen, an organoselenium compound, can permeate the blood-brain barrier and has anti-inflammatory, antioxidant and anticancer activity .
    Ebselen
  • HY-D0041
    Calcein-AM
    80+ Cited Publications

    Calcein acetoxymethyl ester

    		 Fluorescent Dye Cancer
    Calcein AM, has cell membrane permeability and can easily enter the cell. Calcein AM has no fluorescence and is hydrolyzed by endogenous esterase in the cell to produce polar molecule Calcein (Calcein), which has strong negative charge and cannot permeate the cell membrane. Calcein can emit strong green fluorescence, so it is often used with Propidium Iodide for cell viability/virulence detection, excitation/emission wavelength: 494/515 nm .
    Calcein-AM
  • HY-D0150
    Thiazole Orange
    1 Publications Verification

    		 Fluorescent Dye Others
    Thiazole Orange is an asymmetric anthocyanin dye that can be coupled with oligonucleotides (ONs) to prepare fluorescent hybridization probes. Thiazole Orange has been widely used in biomolecular detection and staining of DNA/ RNA in gels and can be used for reticulocyte analysis. Thiazole orange generates a significant fluorescence enhancement and high quantum yield when it binds with nucleic acids, especially RNA. Thiazole orange can permeate living cell membranes. Thiazole orange can use UV light for detection, but can also be detected with blue light. The excitation and emission of Thiazole orange are λex = 510 nm (488 nm and 470 nm also show strong excitation) and λem = 527 nm, respectively .
    Thiazole Orange
  • HY-W012382
    N-Acetyl-L-tyrosine

    		Endogenous Metabolite Metabolic Disease Cancer
    N-Acetyl-L-tyrosine is an orally active endogenous mitochondrial stress response regulator that can permeate the cell membrane by passive diffusion. N-Acetyl-L-tyrosine induces low-level reactive oxygen species (ROS) generation by transiently perturbing mitochondrial membrane potential, triggering reverse signaling to activate FoxO and Keap1 pathways. As a result, N-Acetyl-L-tyrosine enhances the expression of antioxidant enzyme genes, exerting anti-stress and cytoprotective effects. N-Acetyl-L-tyrosine can improve heat stress tolerance, inhibit tumor growth, and regulate energy metabolism. N-Acetyl-L-tyrosine can be used in the research of aging, metabolic diseases (such as diabetes), and cancer .
    N-Acetyl-L-tyrosine
  • HY-33878
    2-PPA

    		Potassium Channel Proton Pump Neurological Disease
    2-PPA is a lysosomal potassium and proton channel TMEM175 pore blocker. 2-PPA binds at a TMEM175 pore site to occlude potassium and proton ion permeation pathways. 2-PPA increases lysosomal macromolecule catabolism, accelerates macropinocytosis. 2-PPA binds to hepatic protein in covalent. 2-PPA can be used for the research of Parkinson's disease .
    2-PPA
  • HY-P99849
    Depatuxizumab

    ABT-806

    		 EGFR Cancer
    Depatuxizumab is a brain-penetrant and humanized tumor-specific anti EGFR monoclonal antibody. Depatuxizumab inhibits the growth of xenograft models of mutant EGFRvIII and wild-type EGFR. Depatuxizumab can be used for research on cancer .
    Depatuxizumab
  • HY-P4210
    Sulanemadlin
    1 Publications Verification

    ALRN-6924; MP-4897

    		 MDM-2/p53 Cancer
    Sulanemadlin (ALRN-6924) is a potent and cell-permeating p53-based peptidomimetic macrocycles. Sulanemadlin is a inhibitor of the p53-MDM2, p53-MDMX, or both p53 and MDM2 and MDMX protein-protein interactions. Sulanemadlin can be used for cancers research .
    Sulanemadlin
  • HY-DY1036
    Calcein-AM (solution)

    		Fluorescent Dye Cancer
    Calcein AM (solution) , has cell membrane permeability and can easily enter the cell. Calcein AM has no fluorescence and is hydrolyzed by endogenous esterase in the cell to produce polar molecule Calcein (Calcein) , which has strong negative charge and cannot permeate the cell membrane. Calcein can emit strong green fluorescence, so it is often used with Propidium Iodide for cell viability/virulence detection, excitation/emission wavelength: 494/515 nm .
    Solvent and concentration: DMSO: 2 mM
    Calcein-AM (solution)
  • HY-W141881
    N-Lauroylsarcosine

    		Environmental Pollutants Biochemical Assay Reagents HSV Infection
    N-lauroylsarcosine is an anionic surfactant. N-lauroylsarcosine has antiviral activity against HSV-2 strain 333 and HSV-1 strain F. N-lauroylsarcosine synergistically increases skin permeability with 25-50% ethanol. N-lauroylsarcosine can be used to study HSV-2 infection .
    N-Lauroylsarcosine
  • HY-112624I
    Dextran T3 (MW 3,000)

    Dextran 3; Dextran D3; Dextran T3(MW 2400-3600)

    		 Bacterial Others
    Dextran T3 (Dextran 3; Dextran T3(MW 2400-3600)) is a neural tracer and intestinal permeability probe that can move anterogradely and retrogradely in neuronal axons by passive diffusion. Dextran T3 (MW 3,000) is able to permeate across the intestinal epithelial cell membrane in the presence of cholera toxin-induced cytoskeletal disturbance. Dextran T3 (MW 3,000) is used as a fluorescent marker to rapidly label developing neurons (such as Xenopus retinal ganglion cells) and to assess intestinal barrier function. It can be used to study axonal transport in neuroanatomy and permeability changes in intestinal pathophysiology. The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong the half-life of drugs, increase local concentrations, and reduce the activity of immune clearance .
    Dextran T3 (MW 3,000)
  • HY-W134328
    Blue dextran (MW 2000000)

    Dextran blue (MW 2000000)

    		 Biochemical Assay Reagents Others
    Blue dextran (Dextran blue) (MW 2000000) is a high-molecular-weight long-chain polymer of D-glucose. Blue dextran (MW 2000000) serves as an important model macromolecular drug and molecular weight estimation marker, and can be used as a standard for gel permeation chromatography. The release of Blue dextran (MW 2000000) from alginate microspheres is regulated by preparation conditions; its release rate in a pH 6.8 environment is significantly faster than that in pH 1.2, and it exhibits release characteristics close to zero-order kinetics under this condition .
    Blue dextran (MW 2000000)
  • HY-W039953
    Ac4GlcNAz

    N-azidoacetylglucosamine-tetraacylated

    		 Biochemical Assay Reagents Others
    Ac4GlcNAz (N-azidoacetylglucosamine-tetraacylated) is an azido-tagged analogue of N-acetylglucosamine (GlcNAC). It features azide functionality on the N-acyl side chain and is acetylated to aid in cell membrane permeation. Once in the cell, the acetylated compound is deprotected and takes part in the hexosamine biosynthetic pathway by action of GlcNAc kinase. The resulting modified proteins are detected by the addition of fluorescent tags under Cu(I)-catalyzed azide-alkyne cycloaddition conditions.
    Ac4GlcNAz
  • HY-W040996R
    2-Octyldodecanol (Standard)

    		Biochemical Assay Reagents Reference Standards Others
    2-Octyldodecanol (Standard) is the analytical standard of 2-Octyldodecanol. This product is intended for research and analytical applications. 2-Octyldodecanol can enhance the skin permeation of formoterol fumarate (HY-B0010) .
    2-Octyldodecanol (Standard)
  • HY-138560
    Cross-linked dextran G 50
    2 Publications Verification

    		 Biochemical Assay Reagents Others
    Cross-linked dextran G 50 is a gel filtration medium. Cross-linked dextran G 50 can be used in gel permeation chromatography for fractionation of the glycopeptide mixture (Sphere protein separation range: 1.5K-30K Da; Polysaccharide separation range: 500-10K Da) .
    Cross-linked dextran G 50
  • HY-W145493
    Glycofurol

    Tetraglycol; Poly(ethylene glycol) tetrahydrofurfuryl ether

    		 Biochemical Assay Reagents Others
    Glycofurol (Tetraglycol) is a hydrophilic, water-miscible cosolvent and absorption enhancer with skin tolerance. Glycofurol can be used as a carrier-based gel for the topical delivery of drugs, including water-insoluble drugs. Glycofurol can form gels with bioadhesiveness, spreadability and suitable viscosity for topical administration .
    Glycofurol
  • HY-W040996
    2-Octyldodecanol

    		Environmental Pollutants Others
    2-Octyldodecanol can enhance the skin permeation of formoterol fumarate (HY-B0010) .
    2-Octyldodecanol
  • HY-N2197
    Hirsuteine
    2 Publications Verification

    		 nAChR Neurological Disease
    Hirsuteine is an indole alkaloid extracted from Uncaria rhynchophylla. Hirsuteine non-competitively antagonizes nicotine-mediated dopamine release by blocking ion permeation through nicotinic receptor channel complexes .
    Hirsuteine
  • HY-114299S
    Salcaprozate-d4 sodium

    SNAC-d4 sodium

    		 Isotope-Labeled Compounds Others
    Salcaprozate-d4 (sodium) is a deuterated labeled Salcaprozate (sodium) . Salcaprozate sodium (SNAC), an oral absorption promoter, and has the potential as a delivery agent for oral forms of heparin and insulin. Salcaprozate sodium could increase passive transcellular permeation across small intestinal epithelia based on increased lipophilicity arising from non-covalent macromolecule complexation .
    Salcaprozate-d4 sodium
  • HY-156045C
    Cross-linked dextran G 200

    		Biochemical Assay Reagents Others
    Cross-linked dextran G 200 is a hydrophilic gel based on molecular size exclusion and targeted macromolecular separation. Cross-linked dextran G 200 works through the gel permeation mechanism, and the cross-linked structure forms a three-dimensional network with a specific pore size, achieving separation based on the molecular hydrodynamic volume. Cross-linked dextran G 200 can be used to adjust the osmotic solute distribution coefficient and the ability to maintain osmotic equilibrium, such as in gel filtration chromatography for purification and analysis of biomacromolecules such as proteins and nucleic acids . Cross-linked dextran G 200 can also be used as a gel filtration filler (particle size range: 40-120 μm; globular protein separation range: 5-600 kDa) .
    Cross-linked dextran G 200
  • HY-W127730
    Pyridoxine 3,4-dipalmitate

    		Drug Derivative Others
    Pyridoxine 3,4-dipalmitate is a Pyridoxine (HY-B1328) derivative. Pyridoxine exerts its antioxidant effects .
    Pyridoxine 3,4-dipalmitate
  • HY-114299R
    Salcaprozate sodium (Standard)

    SNAC (Standard)

    		 Biochemical Assay Reagents Reference Standards Others
    Salcaprozate (sodium) (Standard) is the analytical standard of Salcaprozate (sodium). This product is intended for research and analytical applications. Salcaprozate sodium (SNAC), an oral absorption promoter, and has the potential as a delivery agent for oral forms of heparin and insulin. Salcaprozate sodium could increase passive transcellular permeation across small intestinal epithelia based on increased lipophilicity arising from non-covalent macromolecule complexation .
    Salcaprozate sodium (Standard)
  • HY-156045B
    Cross-linked dextran G 150

    		Biochemical Assay Reagents Others
    Cross-linked dextran G 150 is a hydrophilic gel based on molecular size exclusion and targeted for the separation of macromolecules. Cross-linked dextran G 150 functions through the gel permeation mechanism, where the cross-linked structure forms a three-dimensional network with specific pore diameters, achieving separation based on the molecular volumetric flow. Cross-linked dextran G 150 can be used to regulate the distribution coefficient of permeating solutes and maintain the permeation balance, such as in gel filtration chromatography for the purification and analysis of biological macromolecules like proteins and nucleic acids. Cross-linked dextran G 150 can also be used as a gel filtration filler (particle size range: 40-120 μm; spherical protein separation range: 5-300 kDa) .
    Cross-linked dextran G 150
  • HY-120536
    HPi1
    1 Publications Verification

    		 Bacterial Infection
    HPi1 is a potent, selective and orally active antimicrobial against Helicobacter pylori with an IC50 of 0.24 μM and an MIC of 0.08-0.16 μg/mL. HPi1 is inactive against other bacteria, including the gut commensals Lactobacillus casei, Lactobacillus reuteri, and Bifidobacterium longum .
    HPi1
  • HY-101122
    LX2761

    		SGLT GLP Receptor Metabolic Disease
    LX2761 is an orally active, dual SGLT1/SGLT2 inhibitor with IC50 values of 2.2 nM and 2.7 nM against human SGLT1 and SGLT2, respectively. LX2761 locks human SGLT1 in an outward-open conformation and blocks its putative water permeation pathway. After oral administration, LX2761 is confined exclusively to the intestinal lumen, delays intestinal glucose absorption, regulates intestinal glucose metabolism, increases cecal glucose levels, reduces cecal pH, improves glycemic control and elevates plasma total GLP-1 levels. However, LX2761 induces diarrhea in a dose-dependent manner. LX2761 can be used in diabetes-related research .
    LX2761
  • HY-W250316
    Alpha-d-Glucopyranoside, beta-d-fructofuranosyl, octadecanoate

    Sucrose Stearate, Type II, USP

    		 Biochemical Assay Reagents Others
    Alpha-d-Glucopyranoside, beta-d-fructofuranosyl, octadecanoate (Sucrose Stearate, Type II, USP) is a non-ionic surfactant. Alpha-d-Glucopyranoside, beta-d-fructofuranosyl, octadecanoate enhances the skin permeability of formulations .
    Alpha-d-Glucopyranoside, beta-d-fructofuranosyl, octadecanoate
  • HY-W012382S
    N-Acetyl-L-tyrosine-d3

    		Isotope-Labeled Compounds Endogenous Metabolite Metabolic Disease Cancer
    N-Acetyl-L-tyrosine-d3 is the deuterated form of N-Acetyl-L-tyrosine (HY-W012382). N-Acetyl-L-tyrosine is an orally active endogenous mitochondrial stress response regulator that can permeate the cell membrane by passive diffusion. N-Acetyl-L-tyrosine induces low-level reactive oxygen species (ROS) generation by transiently perturbing mitochondrial membrane potential, triggering reverse signaling to activate FoxO and Keap1 pathways. As a result, N-Acetyl-L-tyrosine enhances the expression of antioxidant enzyme genes, exerting anti-stress and cytoprotective effects. N-Acetyl-L-tyrosine can improve heat stress tolerance, inhibit tumor growth, and regulate energy metabolism. N-Acetyl-L-tyrosine can be used in the research of aging, metabolic diseases (such as diabetes), and cancer .
    N-Acetyl-L-tyrosine-d3
  • HY-141661
    Aβ/tau aggregation-IN-1

    		Amyloid-β Neurological Disease
    Aβ/tau aggregation-IN-1 is a potent Aβ1-42 β-sheets formation and tau aggregation inhibitor. The KD values of Aβ/tau aggregation-IN-1 with Aβ1-42 and tau are 160 μM and 337 μM, respectively. Aβ/tau aggregation-IN-1 can permeate the blood-brain barrier .
    Aβ/tau aggregation-IN-1
  • HY-P3896
    Substance P (2-11)

    		Neurokinin Receptor Neurological Disease
    Substance P (2-11) is a substance P (SP) fragment peptide. Substance P (2-11) has contracting activities on guinea pig ileum. Substance P (2-11) inhibits the permeation of 3H SP in BBMEC monolayers .
    Substance P (2-11)
  • HY-117843
    Ppc-1

    		Mitochondrial Metabolism Interleukin Related Bacterial Infection Metabolic Disease Inflammation/Immunology
    Ppc-1 is a mitochondrial uncoupler. Ppc-1 enhances mitochondrial oxygen consumption without adverse effects on ATP production. Ppc-1 is a cell-permeate interleukin-2 (IL-2) inhibitor. Ppc-1 inhibits the Gram-negative periodontopathogen Porphyromonas gingivalis. Ppc-1 has anti-obesity, antibacterial and anti-inflammatory activities .
    Ppc-1
  • HY-D1585
    BODIPY TR methyl ester

    		Fluorescent Dye Others
    BODIPY TR methyl ester is a lipophilic GFP Counterstain. BODIPY TR methyl ester dye readily permeates cell membranes and localizes in endomembranous organelles but not localize strongly in plasma membranes. BODIPY TR methyl ester is an excellent red fluorescent vital dye (Ex=568 nm, Em=625 nm), can be used to reveal the location and shapes of cell nuclei, the shapes of cells within embryonic tissues, as well as the bound aries of organ-forming tissues within the whole embryo .
    BODIPY TR methyl ester
  • HY-W004782
    3-Methylthiophene-2-carboxylic acid

    		Bacterial Inflammation/Immunology
    3-Methylthiophene-2-carboxylic acid (compound 3) is a potent Pseudomonas quinolone signal system protein E (PqsE) inhibitor with a Kd of 19.6 µM and an IC50 of 40 µM. 3-Methylthiophene-2-carboxylic acid binds to the active center of PqsE and shows inhibition of the thioesterase activity. Methylthiophene-2-carboxylic acid can permeate into P. aeruginosa and affect 2,4-dihydroxyquinoline (DHQ) levels to a similar extent as deletion of the PqsE gene. 3-Methylthiophene-2-carboxylic acid can be used for cystic fibrosis research .
    3-Methylthiophene-2-carboxylic acid
  • HY-W012382R
    N-Acetyl-L-tyrosine (Standard)

    		Reference Standards Endogenous Metabolite Metabolic Disease Cancer
    N-Acetyl-L-tyrosine (Standard) is the analytical standard of N-Acetyl-L-tyrosine (HY-W012382). This product is intended for research and analytical applications. N-Acetyl-L-tyrosine is an orally active endogenous mitochondrial stress response regulator that can permeate the cell membrane by passive diffusion. N-Acetyl-L-tyrosine induces low-level reactive oxygen species (ROS) generation by transiently perturbing mitochondrial membrane potential, triggering reverse signaling to activate FoxO and Keap1 pathways. As a result, N-Acetyl-L-tyrosine enhances the expression of antioxidant enzyme genes, exerting anti-stress and cytoprotective effects. N-Acetyl-L-tyrosine can improve heat stress tolerance, inhibit tumor growth, and regulate energy metabolism. N-Acetyl-L-tyrosine can be used in the research of aging, metabolic diseases (such as diabetes), and cancer .
    N-Acetyl-L-tyrosine (Standard)
  • HY-W1113135
    Carboxymethyl-β-cyclodextrin sodium salt

    		Biochemical Assay Reagents Others
    Carboxymethyl-β-cyclodextrin sodium salt is a negatively charged β-cyclodextrin derivative, as well as a metal ion chelator and solubilizing reagent. Carboxymethyl-β-cyclodextrin sodium salt forms stable aqueous complexes with Ba 2+, Ca 2+, Cd 2+, Ni 2+, Pb 2+, Sr 2+, and Zn 2+ ions. Carboxymethyl-β-cyclodextrin sodium salt derived hydrogel carriers support oral insulin delivery via paracellular permeation across Caco-2 monolayers and produce sustained hypoglycemic effects in diabetic mice. Carboxymethyl-β-cyclodextrin sodium salt can be conjugated onto folate-modified BSA nanoparticles to boost folate receptor-mediated endocytosis, elevate intracellular anticancer drug uptake and trigger cell apoptosis. Carboxymethyl-β-cyclodextrin sodium salt can be utilized for chiral separation in capillary electrophoresis, development of nanoscale drug carriers and nucleic acid transfection research .
    Carboxymethyl-β-cyclodextrin sodium salt
  • HY-P5727
    HR1

    		Bacterial Infection
    HR1 is a mastoid protease. HR1 can increase the permeability of human erythrocyte membrane. HR1 can induce cytoplasmic membrane permeation in bacteria and mast cells .
    HR1
  • HY-P10325
    Kalata B7

    		Vasopressin Receptor Oxytocin Receptor Cardiovascular Disease
    Kalata B7 is a cyclotide that can be isolated from Oldenlandia affinis DC (Rubiaceae) and possesses membrane-permeating capabilities. Kalata B7 is also a partial agonist of oxytocin and vasopressin V1a receptors .
    Kalata B7
  • HY-110255
    AZD 2066
    1 Publications Verification

    		 mGluR Calcium Channel Trk Receptor Neurological Disease
    AZD-2066 is a selective, orally active and blood-brain barrier-permeating mGluR5 antagonist. AZD 2066 activates the BDNF/trkB signaling pathway. AZD 2066 can be used in the research of neuropathic pain, major depressive disorder and gastroesophageal reflux disease .
    AZD 2066
  • HY-119151
    GS-9191

    		Apoptosis HPV DNA/RNA Synthesis Infection
    GS-9191 is the prodrug of the nucleotide analog PMEG. GS-9191 is a topical agent to permeate skin and be metabolized to the active nucleoside triphosphate analog in the epithelial layer. GS-9191 inhibits NA synthesis, arrests cell in S phase, and induces cell apoptosis. GS-9191 can be used for research of human papillomaviruses (HPV) infection .
    GS-9191
  • HY-P10618
    BTM-P1

    		Bacterial Infection
    BTM-P1 is a polycationic peptide that exhibits antibacterial activity against both Gram-positive and Gram-negative bacteria. BTM-P1 can form ion-permeable channels in the inner mitochondrial membrane to interfere with mitochondrial energy processes .
    BTM-P1
  • HY-138560A
    Cross-linked dextran G 50, medium

    		Biochemical Assay Reagents Others
    Cross-linked dextran G 50, medium is a gel filtration medium. Cross-linked dextran G 50, medium can be used in gel permeation chromatography for fractionation of the glycopeptide mixture (Sphere protein separation range: 1.5K-30K Da; Polysaccharide separation range: 500-10K Da). Cross-linked dextran G 50, medium are microspheres with an average particle size of D50 = 220-250 μm .
    Cross-linked dextran G 50, medium
  • HY-138560B
    Cross-linked dextran G 50, fine

    		Biochemical Assay Reagents Others
    Cross-linked dextran G 50, fine is a gel filtration medium. Cross-linked dextran G 50, fine can be used in gel permeation chromatography for fractionation of the glycopeptide mixture (Sphere protein separation range: 1.5K-30K Da; Polysaccharide separation range: 500-10K Da). Cross-linked dextran G 50, fineThe average particle size is D50=110-130 μmof microspheres .
    Cross-linked dextran G 50, fine
  • HY-N7132R
    (-)-Menthyl acetate (Standard)

    L-Menthyl acetate (Standard)

    		 Reference Standards Others Others
    (-)-Menthyl acetate (Standard) is the analytical standard of Menthyl acetate. This product is intended for research and analytical applications. (-)-Menthyl acetate (L-Menthyl acetate) is a derivative of L-menthol. (-)-Menthyl acetate is effective to enhance 5-aminolevulinic acid (ALA) skin permeation .
    (-)-Menthyl acetate (Standard)
  • HY-151389
    BChE-IN-14

    		Cholinesterase (ChE) Neurological Disease
    BChE-IN-14 (compound 19c) is a selective butyrylcholinesterase (BChE) inhibitor with IC50s of 0.23 and 0.011 μM for eqBChE and hBChE, respectively. BChE-IN-14 shows good blood brain barrier permeation and primary cell safety. BChE-IN-14 is able to restore cognitive impairment in vivo, it can be used for the research of Alzheimer’s disease .
    BChE-IN-14
  • HY-N15450
    Undulatine

    		Cholinesterase (ChE) Neurological Disease
    Undulatine is a potent AChE inhibitor with an IC50 of 7.4 μM. Undulatine is able to cross the BBB by passive permeation and can be used in the study of Alzheimer’s disease .
    Undulatine
  • HY-W893751
    PMO-G

    		Biochemical Assay Reagents Metabolic Disease
    PMO-G is a spherical-shape polymeric micelles. PMO-G has skin permeation. PMO-G can result in up to a 50-fold higher level of dystrophin in abdominal muscles of mdx mice. PMO-G can be studied in research on Duchenne muscular dystrophy .
    PMO-G
  • HY-110255A
    AZD 2066 hydrate

    		mGluR Calcium Channel Trk Receptor Neurological Disease
    AZD-2066 hydrate is a selective, orally active and blood-brain barrier-permeating mGluR5 antagonist. AZD 2066 hydrate activates the BDNF/trkB signaling pathway. AZD 2066 hydrate can be used in the research of neuropathic pain, major depressive disorder and gastroesophageal reflux disease .
    AZD 2066 hydrate
  • HY-110255B
    AZD-2066 hydrochloride

    		mGluR Calcium Channel Trk Receptor Neurological Disease
    AZD-2066 hydrochloride is a selective, orally active and blood-brain barrier-permeating mGluR5 antagonist. AZD 2066 hydrochloride activates the BDNF/trkB signaling pathway. AZD 2066 hydrochloride can be used in the research of neuropathic pain, major depressive disorder and gastroesophageal reflux disease .
    AZD-2066 hydrochloride
  • HY-W598230A
    m-PEG2000-NH2 hydrochloride

    		Biochemical Assay Reagents Others
    m-PEG2000-NH2 hydrochloride is a barrier permeation compound involved in the preparation of hybrid gels with adsorption and size exclusion chromatography (AdSEC) properties. m-PEG-NH2 helps AdSEC gels separate from complex biological mixtures such as blood, urine, sweat, and tears.
    m-PEG2000-NH2 hydrochloride
  • HY-N7539
    Cognac oil

    		Others Metabolic Disease
    Cognac oil, mainly found in wine lees, has unique fatty acid profiles, including Palmitic acid (59.26%), Linoleic acid (11.92%), Myristic acid (8.97%), Oleic acid (8.3%) and other fatty acids. Cognac oil leads to a general increase in the permeation of R6G (Rhodamine 6G) across all the membranes .
    Cognac oil

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