537-55-3
537-55-3
Chemical Structure
N-Acetyl-L-tyrosine
- CAS No.: 537-55-3
- Formula:C11H13NO4
- Molecular Weight:223.23
IUPAC Name: acetyl-L-tyrosine
InChIKey: CAHKINHBCWCHCF-JTQLQIEISA-N
SMILES: OC1=CC=C(C=C1)C[C@@H](C(O)=O)NC(C)=O
Biological Activity: N-Acetyl-L-tyrosine is an orally active endogenous mitochondrial stress response regulator that can permeate the cell membrane by passive diffusion. N-Acetyl-L-tyrosine induces low-level reactive oxygen species (ROS) generation by transiently perturbing mitochondrial membrane potential, triggering reverse signaling to activate FoxO and Keap1 pathways. As a result, N-Acetyl-L-tyrosine enhances the expression of antioxidant enzyme genes, exerting anti-stress and cytoprotective effects. N-Acetyl-L-tyrosine can improve heat stress tolerance, inhibit tumor growth, and regulate energy metabolism. N-Acetyl-L-tyrosine can be used in the research of aging, metabolic diseases (such as diabetes), and cancer[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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N-Acetyl-L-tyrosine | 99.48% | N-Acetyl-L-tyrosine is an orally active endogenous mitochondrial stress response regulator that can permeate the cell membrane by passive diffusion. N-Acetyl-L-tyrosine induces low-level reactive oxygen species (ROS) generation by transiently perturbing mitochondrial membrane potential, triggering reverse signaling to activate FoxO and Keap1 pathways. As a result, N-Acetyl-L-tyrosine enhances the expression of antioxidant enzyme genes, exerting anti-stress and cytoprotective effects. N-Acetyl-L-tyrosine can improve heat stress tolerance, inhibit tumor growth, and regulate energy metabolism. N-Acetyl-L-tyrosine can be used in the research of aging, metabolic diseases (such as diabetes), and cancer. | ||||||||||||||||||||
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N-Acetyl-L-tyrosine (Standard) | 99.57% | N-Acetyl-L-tyrosine (Standard) is the analytical standard of N-Acetyl-L-tyrosine (HY-W012382). This product is intended for research and analytical applications. N-Acetyl-L-tyrosine is an orally active endogenous mitochondrial stress response regulator that can permeate the cell membrane by passive diffusion. N-Acetyl-L-tyrosine induces low-level reactive oxygen species (ROS) generation by transiently perturbing mitochondrial membrane potential, triggering reverse signaling to activate FoxO and Keap1 pathways. As a result, N-Acetyl-L-tyrosine enhances the expression of antioxidant enzyme genes, exerting anti-stress and cytoprotective effects. N-Acetyl-L-tyrosine can improve heat stress tolerance, inhibit tumor growth, and regulate energy metabolism. N-Acetyl-L-tyrosine can be used in the research of aging, metabolic diseases (such as diabetes), and cancer. | ||||||||||||||||||||
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H-Gly-D-Tyr-OH | H-Gly-D-Tyr-OH is used for the the solid-phase peptide synthesis. | |||||||||||||||||||||
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N-Pivaloyl-L-tyrosine | N-Pivaloyl-L-tyrosine is an N-pivaloyl amino acid ester. | |||||||||||||||||||||
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Lactoyl-L-tyrosine | Lactoyl-L-tyrosine is an endogenous N-lactoyl-amino acid formed from L-lactic acid and L-tyrosine. Lactoyl-L-tyrosine can be used to study flavor development during cheese ripening or as a natural flavor enhancer in the food industry. | |||||||||||||||||||||
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H-Ser-Tyr-OH | 98.87% | H-Ser-Tyr-OH is a dipeptide. H-Ser-Tyr-OH can form a copper(II) complex. | ||||||||||||||||||||
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H-Val-Tyr-OH | 99.11% | H-Val-Tyr-OH (Val-Tyr) is a dipeptide formed by the connection of valine and tyrosine via a peptide bond. H-Val-Tyr-OH is a potential IKKα inhibitor and can be used in the research of cancer and inflammatory diseases. | ||||||||||||||||||||
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Glycyl-L-tyrosine | 99.45% | Glycyl-L-tyrosine is a synthetic dipeptide that can be used as a food additive for tyrosine supplementation. | ||||||||||||||||||||
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Glycyl-L-tyrosine dihydrate | 98.13% | Glycyl-L-tyrosine dihydrate is a synthetic dipeptide that can be used as a food additive for tyrosine supplementation. | ||||||||||||||||||||
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L-Alanyl-L-tyrosin | 99.94% | L-Alanyl-L-tyrosin is a tyrosine derivative. | ||||||||||||||||||||
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Ac-Tyr-OEt.H2O | 98.57% | Ac-Tyr-OEt.H2O is a tyrosine derivative. | ||||||||||||||||||||
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N-Acetyl-L-tyrosine ethyl ester | 99.76% | N-Acetyl-L-tyrosine ethyl ester (ATEE) is a compound commonly used as a food flavoring and supplement. It is an ester of tyrosine, an amino acid found in many proteins. N-Acetyl-L-tyrosine ethyl ester is sweet, nutty and caramelized and is commonly used to enhance the flavor of baked goods, dairy products and beverages. Potential health benefits of N-Acetyl-L-tyrosine ethyl ester include its antioxidant properties and ability to improve cognitive function. | ||||||||||||||||||||
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References
- [1]. Bjelton, Lilian, et al. N-acetyl-L-tyrosine as a source of tyrosine in intravenous nutrition an experimental study in the rat. Nutrition Research 9.5 (1989): 555-564.
- [2]. Matsumura T, et al. N-acetyl-l-tyrosine is an intrinsic triggering factor of mitohormesis in stressed animals. EMBO Rep. 2020 May 6;21(5):e49211. [Content Brief]
- [3]. Kumar R, et al. Synthesis and evaluation of N-acetyl-L-tyrosine based compounds as PPARalpha selective activators. Eur J Med Chem. 2007 Apr;42(4):503-10. [Content Brief]
