537-55-3
Chemical Structure
N-Acetyl-L-tyrosine
- CAS No.: 537-55-3
- Formula:C11H13NO4
- Molecular Weight:223.23
IUPAC Name: acetyl-L-tyrosine
InChIKey: CAHKINHBCWCHCF-JTQLQIEISA-N
SMILES: OC1=CC=C(C=C1)C[C@@H](C(O)=O)NC(C)=O
Biological Activity: N-Acetyl-L-tyrosine is an orally active endogenous mitochondrial stress response regulator that can permeate the cell membrane by passive diffusion. N-Acetyl-L-tyrosine induces low-level reactive oxygen species (ROS) generation by transiently perturbing mitochondrial membrane potential, triggering reverse signaling to activate FoxO and Keap1 pathways. As a result, N-Acetyl-L-tyrosine enhances the expression of antioxidant enzyme genes, exerting anti-stress and cytoprotective effects. N-Acetyl-L-tyrosine can improve heat stress tolerance, inhibit tumor growth, and regulate energy metabolism. N-Acetyl-L-tyrosine can be used in the research of aging, metabolic diseases (such as diabetes), and cancer[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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N-Acetyl-L-tyrosine | 99.48% | N-Acetyl-L-tyrosine is an orally active endogenous mitochondrial stress response regulator that can permeate the cell membrane by passive diffusion. N-Acetyl-L-tyrosine induces low-level reactive oxygen species (ROS) generation by transiently perturbing mitochondrial membrane potential, triggering reverse signaling to activate FoxO and Keap1 pathways. As a result, N-Acetyl-L-tyrosine enhances the expression of antioxidant enzyme genes, exerting anti-stress and cytoprotective effects. N-Acetyl-L-tyrosine can improve heat stress tolerance, inhibit tumor growth, and regulate energy metabolism. N-Acetyl-L-tyrosine can be used in the research of aging, metabolic diseases (such as diabetes), and cancer. | ||||||||||||||||||||
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N-Acetyl-L-tyrosine (Standard) | 99.57% | N-Acetyl-L-tyrosine (Standard) is the analytical standard of N-Acetyl-L-tyrosine (HY-W012382). This product is intended for research and analytical applications. N-Acetyl-L-tyrosine is an orally active endogenous mitochondrial stress response regulator that can permeate the cell membrane by passive diffusion. N-Acetyl-L-tyrosine induces low-level reactive oxygen species (ROS) generation by transiently perturbing mitochondrial membrane potential, triggering reverse signaling to activate FoxO and Keap1 pathways. As a result, N-Acetyl-L-tyrosine enhances the expression of antioxidant enzyme genes, exerting anti-stress and cytoprotective effects. N-Acetyl-L-tyrosine can improve heat stress tolerance, inhibit tumor growth, and regulate energy metabolism. N-Acetyl-L-tyrosine can be used in the research of aging, metabolic diseases (such as diabetes), and cancer. | ||||||||||||||||||||
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Similarity Score 0.87
HY-131094H-Gly-D-Tyr-OH -
Similarity Score 0.87
HY-W009592Glycyl-L-tyrosine -
Similarity Score 0.86
HY-174290Lactoyl-L-tyrosine -
Similarity Score 0.86
HY-W011903L-Alanyl-L-tyrosin -
Similarity Score 0.86
HY-131112N-Pivaloyl-L-tyrosine -
Similarity Score 0.85
HY-W009592AGlycyl-L-tyrosine dihydrate -
Similarity Score 0.84
HY-W236261N-Acetyl-L-tyrosine ethyl ester -
Similarity Score 0.83
HY-W013322Ac-Tyr-OEt.H2O -
Similarity Score 0.81
HY-P4531H-Ser-Tyr-OH -
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References
- [1]. Bjelton, Lilian, et al. N-acetyl-L-tyrosine as a source of tyrosine in intravenous nutrition an experimental study in the rat. Nutrition Research 9.5 (1989): 555-564.
- [2]. Matsumura T, et al. N-acetyl-l-tyrosine is an intrinsic triggering factor of mitohormesis in stressed animals. EMBO Rep. 2020 May 6;21(5):e49211. [Content Brief]
- [3]. Kumar R, et al. Synthesis and evaluation of N-acetyl-L-tyrosine based compounds as PPARalpha selective activators. Eur J Med Chem. 2007 Apr;42(4):503-10. [Content Brief]
