6 Results for "

primary human CD8+ T cells

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "primary human CD8+ T cells" in MCE Product Catalog:

Cat. No.: HY-P11356
CAS No.: 1932689-39-8
Target:  

Ras MHC

Research Areas:  

Cancer

KRAS G12V Peptide is a polypeptide and epitope derived from KRAS G12V. KRAS G12V Peptide forms a stable, high-affinity peptide-HLA class I complex, which is processed and presented by tumor cells and can be recognized by specific TCR. KRAS G12V Peptide is applicable to research related to metastatic lung cancer .
loading...
    loading...
Cat. No.: HY-P11356A
Target:  

Ras MHC

Research Areas:  

Cancer

KRAS G12V Peptide TFA is a polypeptide and epitope derived from KRAS G12V. KRAS G12V Peptide TFA forms a stable, high-affinity peptide-HLA class I complex, which is processed and presented by tumor cells and can be recognized by specific TCR. KRAS G12V Peptide TFA is applicable to research related to metastatic lung cancer .
loading...
    loading...
Cat. No.: HY-P992408

Research Areas:  

Cancer

MEDI-5083 is an Fc fusion protein that targets CD40 and is a CD40 agonist. MEDI-5083 stimulates CD40 signaling via NF-κB activation. MEDI-5083 upregulates MHCII, CD80, and CD86 expression, induces pro-inflammatory cytokine secretion, and enhances IFN-γ secretion by memory CD8+ T cells. MEDI-5083 can be used for the research of melanoma, colon carcinoma, and advanced solid tumors[1][2].
loading...
    loading...
Cat. No.: HY-183887
CAS No.: 324054-99-1
Target:  

PD-1/PD-L1

Research Areas:  

Cancer

PD-L1-IN-11 is a PD-L1 inhibitor with human PD-L1 IC50 and KD of 27.82 μM and 49.50 μM, respectively. PD-L1-IN-11 directly binds to PD-L1 via a dimer-locking mechanism, occluding the PD-1 interaction surface to disrupt PD-1/PD-L1 interaction. PD-L1-IN-11 can be used for the research of melanoma, colon carcinoma .
loading...
    loading...
Cat. No.: HY-182693
CAS No.: 2019223-60-8
CPL302-253 is a PI3Kδ inhibitor with an IC50 of 12.20 nM and a human Kd of 0.85 nM. CPL302-253 functionally regulates PI3Kδ activity, blocks the production of IFNγ, IL-33 and ROS in immune cells, and affects immune function. CPL302-253 blocks the progression of asthma-inducing inflammatory responses in a mouse model of asthma. CPL302-253 can be used for research related to asthma .
loading...
    loading...
Cat. No.: HY-188022
CAS No.: 3024023-96-6
Target:  

Liposome

Research Areas:  

Cardiovascular Disease Cancer

T Cell Lipid 15 is an ionizable cationic lipid. T Cell Lipid 15 can be used to construct LNP targeting T cells. LNPs based on T Cell Lipid 15 induce reduced cytokine secretion, enable specific in vivo CD8 + T cell reprogramming, and cause minimal off-target transfection. T Cell Lipid 15 can be used for research on hematologic malignancies .
loading...
    loading...