3 Results for "

purine biosynthetic pathway

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "purine biosynthetic pathway" in MCE Product Catalog:

2
8-Azaguanine
8-Azaguanine
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2 Cited Publications
Cat. No.: HY-B1468
CAS No.: 134-58-7
Category:  

Natural Products Endogenous metabolite Disease Research Fields Cancer

Target:  

Nucleoside Antimetabolite/Analog Endogenous Metabolite

8-Azaguanine is a purine analogue that shows antineoplastic activity. 8-Azaguanine functions as an antimetabolite and easily incorporates into ribonucleic acids, interfering with normal biosynthetic pathways, thus inhibiting cellular growth .
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1
N-Carbamoyl-L-aspartic acid
N-Carbamoyl-L-aspartic acid
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1 Cited Publications
Cat. No.: HY-128425A
CAS No.: 13184-27-5
Purity:  ≥98.0%
Synonyms: L-Ureidosuccinic acid
Category:  

Natural Products Other Diseases Endogenous metabolite Disease Research Fields

Target:  

Fungal

N-Carbamoyl-L-aspartic acid (L-Ureidosuccinic acid) is an important pyrimidine metabolic precursor and intermediate metabolite. N-Carbamoyl-L-aspartic acid reverses the growth inhibition of Ura + strains induced by 2-thiouracil (with growth rate increasing linearly with its concentration), but fails to support the growth of uracil-requiring Ura - strains. N-Carbamoyl-L-aspartic acid inhibits the cell growth of *Saccharomyces cerevisiae* by suppressing the purine biosynthetic pathway at a pre-step of 5-aminoimidazole nucleotide synthesis. The growth inhibitory effect of N-Carbamoyl-L-aspartic acid on yeast can be alleviated by purines, and the sensitivity of strains is closely related to the activity level of dihydroorotase .
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8-Azaguanine (Standard)
8-Azaguanine (Standard)
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Cat. No.: HY-B1468R
CAS No.: 134-58-7
Category:  

Natural Products Endogenous metabolite

Target:  

Nucleoside Antimetabolite/Analog Endogenous Metabolite Reference Standards

8-Azaguanine (Standard) is the analytical standard of 8-Azaguanine. This product is intended for research and analytical applications. 8-Azaguanine is a purine analogue that shows antineoplastic activity. 8-Azaguanine functions as an antimetabolite and easily incorporates into ribonucleic acids, interfering with normal biosynthetic pathways, thus inhibiting cellular growth .
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