1 Result for "

rabbit gastrocnemius muscle

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "rabbit gastrocnemius muscle" in MCE Product Catalog:

Magnocurarine chloride
Magnocurarine chloride
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Cat. No.: HY-N6609B
CAS No.: 75413-87-5
Category:  

Alkaloids Tiliacora racemosa Colebr. Plants Isoquinoline Alkaloids Menispermaceae

Target:  

nAChR

Magnocurarine chloride is a neuromuscular junction blocker that inhibits muscle contraction by functionally blocking signal transmission without directly damaging nerve or muscle tissues. In frog, mouse and rabbit models, Magnocurarine chloride exerts a dose-dependent paralytic effect, which progresses gradually from limb weakness and loss of righting reflex to respiratory depression and even cardiac arrest. Although high doses cause complete cessation of movement, Magnocurarine chloride does not affect the spinal multineuronal reflex in frogs. Magnocurarine chloride exhibits biological activity similar to that of tubocurarine (HY-125901) in various animal models .
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