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rat-heart mitochondria

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W436366
    SSR180575

    		GABA Receptor Mitochondrial Metabolism Cardiovascular Disease
    SSR180575 is a specific and potent peripheral benzodiazepine receptor ligand. SSR180575 irreversibly and specifically binds with high affinity on rat heart mitochondria (Kd = 1.95 nM). SSR180575 can be used in the research of cardiovascular diseases .
    SSR180575
  • HY-46286
    TTFB

    N-(4-tert-butyl-1,3-thiazol-2-yl)-3-fluorobenzamide

    		 5-HT Receptor nAChR GABA Receptor Glycine Receptor (GlyR) Neurological Disease
    TTFB (N-(4-tert-butyl-1,3-thiazol-2-yl)-3-fluorobenzamide) is a selective, non-competitive zinc-activated channel (ZAC) antagonist. TTFB inhibits Zn 2+- and H +-induced ZAC currents with IC50 values of 3 μM and 8.5 μM, respectively, and has an IC50 of 4.7 μM against spontaneous activity. TTFB shows no significant agonistic, antagonistic or modulatory activity towards representative classical Cys-loop receptors including m5-HT3AR, hα3β4 nAChR, hα1β2γ2S GABAAR and hα1 GlyR. TTFB can be used to investigate the physiological and pathological functions of ZAC.
    TTFB

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