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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
23 Results for "
retrovirus
" in MedChemExpress (MCE) Product Catalog:
Products (23)
23 Results for "retrovirus" in MCE Product Catalog:
115
115 Publications Verification
Synonyms: Polybrene; 1,5-Dimethyl-1,5-diazaundecamethylene polymethobromide
1
1 Cited Publications
dTAG-47 is a heterobifunctional PROTAC degrader that specifically binds to the FKBP12 F36V domain and Cereblon (CRBN). By recruiting the CRBN E3 ubiquitin ligase, dTAG-47 induces ubiquitination and proteasomal degradation of FKBP12 F36V-fused Cas9 and tagged KDM5A. dTAG-47 can induce upregulated expression of some endogenous retrovirus (ERV) genes and is suitable for cancer research .
1
1 Cited Publications
Cat. No.: HY-137640C
CAS No.: 925456-59-3
Target:
Research Areas:
Rp-8-Br-cAMPS sodium is an analog of cAMP and an inhibitor of PKA. Rp-8-Br-cAMPS sodium occupies cAMP binding sites on PKA type I regulatory subunits, thereby preventing PKA dissociation and activation. Rp-8-Br-cAMPS sodium can be used in the study of tumors and retrovirus-induced immune deficiency. Rp-8-Br-cAMPS sodium also inhibits insulin secretion .
(S)-Batylalcohol (1-O-Octadecyl-sn-glycerol) is a phosphonoformic acid (PFA) analog that exhibits higher in vitro antiviral activity against human immunodeficiency virus type 1 (HIV-1) than PFA. (S)-Batylalcohol can be used in antiretroviral research .
Cat. No.: HY-W012311
CAS No.: 3416-05-5
Synonyms: 2′,3′-Dideoxythymidine; ddThd
Research Areas:
3′-Deoxythymidine (2′,3′-Dideoxythymidine), a nucleoside analog, inhibits eukaryotic cellular and viral DNA polymerases, and inhibits retrovirus infection in some cells .
Cat. No.: HY-137640B
CAS No.: 129735-00-8
Target:
Research Areas:
Rp-8-Br-cAMPS is an analog of cAMP and an inhibitor of PKA. Rp-8-Br-cAMPS occupies cAMP binding sites on PKA type I regulatory subunits, thereby preventing PKA dissociation and activation. Rp-8-Br-cAMPS can be used in the study of tumors and retrovirus-induced immune deficiency. Rp-8-Br-cAMPS also inhibits insulin secretion .
Target:
Research Areas:
3'-Azido-3'-deoxy-5-methylcytidine (CS-92) is a potent xenotropic murine leukemia-related retrovirus (XMRV) inhibitor with a CC50 of 43.5 μM in MCF-7 cells. 3'-Azido-3'-deoxy-5-methylcytidine also inhibits HIV-1 reverse transcriptase with an EC50 of 0.06 μM in peripheral blood mononuclear (PBM) cells . 3'-Azido-3'-deoxy-5-methylcytidine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Cat. No.: HY-19577
CAS No.: 85754-59-2
Synonyms: PTT119
Target:
Ambamustine (PTT119) is a bifunctional alkylating agent and induces DNA damage by alkylating mechanisms. Ambamustine interferes with late steps in murine mammary tumor virus (MuMTV) processing and maturation and reduces production of the B-type retrovirus MuMTV. Ambamustine possesses cytolytic and antiviral activities .
Cat. No.: HY-P990809
Target:
Research Areas:
Cat. No.: HY-E70085
Target:
Research Areas:
Moloney murine leukemia virus RT is a monomeric reverse transcriptase from Moloney murine leukemia virus (MMLV). Moloney murine leukemia virus RT is a replicative polymerase that play an essential role in the life cycle of the retrovirus .
Cat. No.: HY-19577A
CAS No.: 83996-50-3
Synonyms: PTT119 hydrochloride
Target:
Ambamustine (PTT119) hydrochloride is a bifunctional alkylating agent and induces DNA damage by alkylating mechanisms. Ambamustine interferes with late steps in murine mammary tumor virus (MuMTV) processing and maturation and reduces production of the B-type retrovirus MuMTV. Ambamustine possesses cytolytic and antiviral activities .
Cat. No.: HY-P703506
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: ERVW-4; Endogenous retrovirus Group W, Member 4; Endogenous retrovirus Group W Member 4; Putative Reverse Transcriptase; C187-23; Pol
Species:
Others
Source:
E. coli
Cat. No.: HY-P71654
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ERVW-1; Endogenous retrovirus Group W, Member 1; Prev. ERVWE1; Envelope Polyprotein GPr73; Syncytin-1; HERV-W Env Glycoprotein; Endogenous retrovirus Group W Member 1; HERV-W Envelope Protein; HERV-7q Envelope Protein; Envelope Glycoprotein; HERV-W-ENV; H
Species:
Human
Source:
E. coli
Cat. No.: HY-P89133A
Synonyms: HERV-H LTR-associating 3; human endogenous retrovirus-H long terminal repeat-associating 3; OTTHUMP00000010943
Cat. No.: HY-P76970
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: HHLA2; B7y; HHLA2 Member Of B7 Family; Human Endogenous retrovirus-H Long Terminal Repeat-Associating Protein 2; B7-H5; HERV-H LTR-Associating Protein 2; B7-H7; HERV-H LTR-Associating 2; B7H7
Species:
Human
Source:
HEK293
Cat. No.: HY-P76971
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: HHLA2; B7y; HHLA2 Member Of B7 Family; Human Endogenous retrovirus-H Long Terminal Repeat-Associating Protein 2; B7-H5; HERV-H LTR-Associating Protein 2; B7-H7; HERV-H LTR-Associating 2; B7H7
Species:
Human
Source:
HEK293
Cat. No.: HY-P81435
Synonyms: SLC1A5 ; ASCT2; M7V1, RDR, RDRC; Neutral amino acid transporter B(0); ATB(0); Baboon M7 virus receptor; RD114/simian type D retrovirus receptor; Sodium-dependent neutral amino acid transporter type 2; Solute carrier family 1 member 5
Cat. No.: HY-P78597
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: HHLA2; B7y; HHLA2 Member Of B7 Family; Human Endogenous retrovirus-H Long Terminal Repeat-Associating Protein 2; B7-H5; HERV-H LTR-Associating Protein 2; B7-H7; HERV-H LTR-Associating 2; B7H7
Species:
Cynomolgus
Source:
HEK293
Cat. No.: HY-P78927
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: HHLA2; B7y; HHLA2 Member Of B7 Family; Human Endogenous retrovirus-H Long Terminal Repeat-Associating Protein 2; B7-H5; HERV-H LTR-Associating Protein 2; B7-H7; HERV-H LTR-Associating 2; B7H7
Species:
Human
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
