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ruthenium(II) polypyridyl complex

" in MedChemExpress (MCE) Product Catalog:

標的別:	Biochemical Assay Reagents (1) Fluorescent Dye (1) Reactive Oxygen Species (ROS) (1)
研究分野別:	Metabolic Disease (1)

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製品番号	製品名	Target	研究分野	構造式

HY-W127832

Ru(dpp)3(PF6)2 1 Publications Verification	Fluorescent Dye	Others
Ru(dpp)3(PF6)2 is a ruthenium (II) polypyridine complex and oxygen-sensing luminophore with excellent photostability and bright orange emission properties based on metal-to-ligand charge transfer (MLCT). Ru(dpp)3(PF6)2 undergoes oxygen-induced collisional luminescence quenching following the Stern-Volmer relationship, and can also engage in Förster-type resonance energy transfer with closed-form BTF6. Featuring excellent photophysical and electrochemical properties, Ru(dpp)3(PF6)2 is applied in studies on quenching-type oxygen sensors based on fluorinated ORMOSIL/xerogels and solid-state light-emitting devices .

HY-P11743

Mitochondrial penetrating peptide	Biochemical Assay Reagents Reactive Oxygen Species (ROS)	Metabolic Disease
Mitochondrial penetrating peptide is a peptide sequence (FrFKFrFK-CONH₂) that selectively transports cargo into mitochondria. Mitochondrial penetrating peptide possesses special physicochemical properties, enabling it to selectively translocate dinuclear Ru (II) polypyridine complexes into mitochondria of living mammalian cells without the aid of solvents or membrane permeabilization treatments, thus achieving precise mitochondrial localization and enrichment of the complexes while excluding their distribution in the nucleus. Mitochondrial penetrating peptide enables dynamic monitoring of mitochondrial oxygen concentration and ROS production in living mammalian cells via changes in the luminescence lifetime of the coupled Ru (II) complex .

製品番号	製品名	Type

HY-W127832

Ru(dpp)3(PF6)2 1 Publications Verification	生化学アッセイ試薬
Ru(dpp)3(PF6)2 is a ruthenium (II) polypyridine complex and oxygen-sensing luminophore with excellent photostability and bright orange emission properties based on metal-to-ligand charge transfer (MLCT). Ru(dpp)3(PF6)2 undergoes oxygen-induced collisional luminescence quenching following the Stern-Volmer relationship, and can also engage in Förster-type resonance energy transfer with closed-form BTF6. Featuring excellent photophysical and electrochemical properties, Ru(dpp)3(PF6)2 is applied in studies on quenching-type oxygen sensors based on fluorinated ORMOSIL/xerogels and solid-state light-emitting devices .

Ru(dpp)3(PF6)2

1 Publications Verification

生化学アッセイ試薬

Ru(dpp)3(PF6)2 is a ruthenium (II) polypyridine complex and oxygen-sensing luminophore with excellent photostability and bright orange emission properties based on metal-to-ligand charge transfer (MLCT). Ru(dpp)3(PF6)2 undergoes oxygen-induced collisional luminescence quenching following the Stern-Volmer relationship, and can also engage in Förster-type resonance energy transfer with closed-form BTF6. Featuring excellent photophysical and electrochemical properties, Ru(dpp)3(PF6)2 is applied in studies on quenching-type oxygen sensors based on fluorinated ORMOSIL/xerogels and solid-state light-emitting devices .

製品番号	製品名	Target	研究分野

HY-P11743

Mitochondrial penetrating peptide	Biochemical Assay Reagents Reactive Oxygen Species (ROS)	Metabolic Disease
Mitochondrial penetrating peptide is a peptide sequence (FrFKFrFK-CONH₂) that selectively transports cargo into mitochondria. Mitochondrial penetrating peptide possesses special physicochemical properties, enabling it to selectively translocate dinuclear Ru (II) polypyridine complexes into mitochondria of living mammalian cells without the aid of solvents or membrane permeabilization treatments, thus achieving precise mitochondrial localization and enrichment of the complexes while excluding their distribution in the nucleus. Mitochondrial penetrating peptide enables dynamic monitoring of mitochondrial oxygen concentration and ROS production in living mammalian cells via changes in the luminescence lifetime of the coupled Ru (II) complex .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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