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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
14 Results for "
sheep liver
" in MedChemExpress (MCE) Product Catalog:
Products (14)
14 Results for "sheep liver" in MCE Product Catalog:
1
Clorsulon (L631529; MK401) is an orally active flukicidal agent. Clorsulon inhibits glycolysis, the primary energy production pathway in flukes. Clorsulon is also a competitive inhibitor of 3-phosphoglycolate and ATP, inhibiting glucose utilization and acetate and propionate formation by mature Fasciola hepatica in vitro. Clorsulon can be used in studies of liver fluke (Fasciola hepatica and Fasciola gigantica) infection in calves and sheep .
1
1 Cited Publications
Synonyms: Sorbito, for cell culture; D-Glucitol, for cell culture
Cat. No.: HY-W017068
CAS No.: 102814-08-4
Synonyms: 2'-Deoxyuridine-5'-triphosphate trisodium salt
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dUTP trisodium (2´-Deoxyuridine, 5´-Triphosphate) is the salt form of dUTP. dUTP is a metabolic intermediate in both procaryotes and eucaryotes. dUTP can be used in PCR and RT-PCR to replace dTTP, resulting in the uracil-containing PCR products suitable for most standard applications. dUTP is found to inhibit the enzyme - Cytidine Aminohydrolase from sheep liver .
Cat. No.: HY-W009706
CAS No.: 22131-79-9
Synonyms: Allopydin; W-7320
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Alclofenac (Allopydin) is an orally active prostaglandin synthase inhibitor with anti-inflammatory, analgesic and antipyretic activities. Alclofenac irreversibly inhibits platelet aggregation. Alclofenac can be used in research related to rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, low back pain and sciatica .
Cat. No.: HY-W019704
CAS No.: 1115-47-5
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Synonyms: 1-Perfluoroheptanesulfonic acid; Perfluoroheptanesulphonic acid; PFHpS
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Perfluoroheptanesulfonic acid (1-Perfluoroheptanesulfonic acid; Perfluoroheptanesulphonic acid; PFHpS) is a per- and polyfluoroalkyl substance (PFAS) that penetrates the skin and induces systemic toxicity and immunotoxicity. Perfluoroheptanesulfonic acid reduces the expression of PPARδ in liver tissue; it induces hepatocyte hypertrophy and necrosis in liver tissue and alters serum biochemical markers associated with liver injury. Perfluoroheptanesulfonic acid upregulates genes related to fatty acid metabolism, cell necrosis and inflammation, reduces the relative weights of the spleen and thymus, suppresses humoral immune responses, and alters the composition of immune cell subsets in the spleen and skin. The plasma concentration of Perfluoroheptanesulfonic acid correlates with food intake. Perfluoroheptanesulfonic acid and perfluorooctanesulfonic acid exhibit synchronous pulse events in influent samples from wastewater treatment plants. Perfluoroheptanesulfonic acid can be used in studies related to liver injury and immune system damage .
Cat. No.: HY-130581
CAS No.: 86559-73-1
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Lipid X is a 2,3-diacylglucosamine-1-phosphate that serves as the monosaccharide precursor of lipid A, possessing both LPS antagonist and weak agonist activities. Lipid X exerts protective effects by inhibiting tumor necrosis factor production, monocyte procoagulant activity, and neutrophil priming. Lipid X may induce transient pulmonary hypertension, neutropenia, and mild pyrogenic effects in laboratory animals. Lipid X has low toxicity and no in vitro antibacterial activity, but it significantly reduces mortality following Gram-negative bacterial infection and endotoxin exposure. Lipid X tends to accumulate in liver tissue, binds to circulating cellular components, and can be converted to lipid Y through transesterification. Lipid X can be used in research on Gram-negative bacterial sepsis, endotoxemia, and associated pulmonary hypertension .
Cat. No.: HY-W414548
CAS No.: 4725-24-0
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7α,27-Dihydroxycholesterol is an oxysterol, a human metabolite, and a ligand for EBI2 (GPR183), which is involved in lipid synthesis. 7α,27-Dihydroxycholesterol mediates the chemotaxis of cells expressing EBI2. 7α,27-Dihydroxycholesterol can be converted into 7α,27-dihydroxy-4-cholesten-3-one (HY-W414457), thereby inhibiting HMG-CoA reductase (HMGCR), the rate-limiting enzyme in cholesterol synthesis .
Cat. No.: HY-W017068A
CAS No.: 94736-09-1
Synonyms: 2'-Deoxyuridine-5'-triphosphate sodium salt
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Research Areas:
dUTP sodium is the salt form of dUTP. dUTP is a metabolic intermediate in both procaryotes and eucaryotes. dUTP can be used in PCR and RT-PCR to replace dTTP, resulting in the uracil-containing PCR products suitable for most standard applications. dUTP is found to inhibit the enzyme - Cytidine Aminohydrolase from sheep liver .
Cat. No.: HY-114969
CAS No.: 14437-41-3
Synonyms: NSC 233846; SYD 230; Tremerad
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Cat. No.: HY-W019704R
CAS No.: 1115-47-5
Cat. No.: HY-B0488R
CAS No.: 60200-06-8
Synonyms: L631529 (Standard); MK401 (Standard)
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Clorsulon (Standard) is the analytical standard of Clorsulon (HY-B0488). This product is intended for research and analytical applications. Clorsulon (L631529; MK401) is an orally active flukicidal agent. Clorsulon inhibits glycolysis, the primary energy production pathway in flukes. Clorsulon is also a competitive inhibitor of 3-phosphoglycolate and ATP, inhibiting glucose utilization and acetate and propionate formation by mature Fasciola hepatica in vitro. Clorsulon can be used in studies of liver fluke (Fasciola hepatica and Fasciola gigantica) infection in calves and sheep .
Cat. No.: HY-W517092
CAS No.: 55673-89-7
Synonyms: 1,2,3,4,7,8,9-HpCDF
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1,2,3,4,7,8,9-Heptachlorodibenzofuran (1,2,3,4,7,8,9-HpCDF) is a compound that induces the expression of CYP1A1 and CYP1B1 genes in human peripheral blood lymphocytes, while also promoting the expression of the aryl hydrocarbon receptor repressor (AhRR). 1,2,3,4,7,8,9-Heptachlorodibenzofuran can increase ethoxyresorufin-O-deethylase (EROD) activity in isolated human peripheral blood lymphocytes in a concentration-dependent manner, which serves as a marker of CYP1A1 activity. Furthermore, 1,2,3,4,7,8,9-Heptachlorodibenzofuran exhibits immunosuppressive effects by reducing the number of splenic plaque-forming cells in mice and increasing aryl hydrocarbon hydroxylase (AHH) activity in liver microsomes of mice injected with sheep red blood cells. 1,2,3,4,7,8,9-Heptachlorodibenzofuran can be used in research in the fields of immunology, metabolic diseases, and environmental toxicology .
Cat. No.: HY-N10625A
CAS No.: 2952-70-7
Synonyms: 5α-Cyprinol
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
