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Cat. No.: HY-B0488R

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Clorsulon (Standard)

(Synonyms: L631529 (Standard); MK401 (Standard))

Clorsulon (Standard) is the analytical standard of Clorsulon (HY-B0488). This product is intended for research and analytical applications. Clorsulon (L631529; MK401) is an orally active flukicidal agent. Clorsulon inhibits glycolysis, the primary energy production pathway in flukes. Clorsulon is also a competitive inhibitor of 3-phosphoglycolate and ATP, inhibiting glucose utilization and acetate and propionate formation by mature Fasciola hepatica in vitro. Clorsulon can be used in studies of liver fluke (Fasciola hepatica and Fasciola gigantica) infection in calves and sheep.

For research use only. We do not sell to patients.

CAS No.: 60200-06-8
Formula: C₈H₈Cl₃N₃O₄S₂
Molecular Weight:380.66

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Clorsulon (Standard) Chemical Structure

CAS No.: 60200-06-8

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Product Information

Information

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 60200-06-8
Molecular Weight 380.66
Formula C₈H₈Cl₃N₃O₄S₂
SMILES

O=S(C1=C(/C(Cl)=C(Cl)\Cl)C=C(N)C(S(=O)(N)=O)=C1)(N)=O
Synonyms

L631529 (Standard); MK401 (Standard)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

References

[1]. Mrozik, H., et al., 4-amino-6-(trichloroethenyl)-1,3-benzenedisulfonamide, a new, potent fasciolicide. J Med Chem, 1977. 20(9): p. 1225-7. [Content Brief]

[2]. Meaney, M., et al., Transmission electron microscope study of the ultrastructural changes induced in the tegument and gut of Fasciola hepatica following in vivo drug treatment with clorsulon. Parasitol Res, 2004. 92(3): p. 232-41. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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