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Results for "

sulfhydryls

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Linker (8) Angiotensin-converting Enzyme (ACE) (1) Apoptosis (3) Bacterial (1) Biochemical Assay Reagents (87) Carboxylesterase (CES) (1) Cathepsin (4) Cholinesterase (ChE) (1) Deubiquitinase (3) Drug Derivative (2) Drug Intermediate (3) Endogenous Metabolite (4) Environmental Pollutants (1) Fluorescent Dye (42) Fructose-1,6-bisphosphate aldolase (1) Fungal (1) Glutaminase (1) Glutathione S-transferase (1) HIV (1) HIV Protease (1) Insecticide (1) Isotope-Labeled Compounds (2) Liposome (2) Mitochondrial Metabolism (1) MMP (1) MOFs (1) NF-κB (2) Reactive Oxygen Species (ROS) (1) Reference Standards (3) SOD (1) TRP Channel (1) VEGFR (2)
By Research Areas:	Cancer (25) Cardiovascular Disease (4) Infection (5) Inflammation/Immunology (9) Neurological Disease (5)
Click Chemistry:	DBCO (11)
Oligonucleotides:	Pegylated Lipids (7)

165

Inhibitors & Agonists

Fluorescent Dyes

Biochemical Assay Reagents

Peptides

MCE Kits

Natural
Products

Isotope-Labeled Compounds

Click Chemistry

Oligonucleotides

GMP Molecules

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-D0843

N-Ethylmaleimide 35+ Cited Publications NEM	Cathepsin Deubiquitinase Apoptosis	Others
N-Ethylmaleimide (NEM) derives from maleic acid, it can alkylates free sulfhydryl. N-Ethylmaleimide is an irreversible cysteine protease inhibitor. N-ethylmaleimide specific inhibits phosphate transport in mitochondria. N-Ethylmaleimide inhibits prolyl endopeptidase with an IC₅₀ value of 6.3 μM. N-Ethylmaleimide can be used to modify cysteine residues in proteins and peptides .

HY-148905

p-Aminophenylmercuric acetate Maximum Cited Publications 10 Publications Verification	Cathepsin MMP	Infection
p-Aminophenylmercuric acetate is an organomercurial activator of matrix metalloproteinases (MMP). P-Aminophenylmercuric acetate participates in the activation and inhibition of MMP-8 by attacking protein sulfhydryl or inducing cysteine switching reaction. p-Aminophenylmercuric acetate promotes the shedding of betacellulin precursor (pro-BTC). p-Aminophenylmercuric acetate influences the binding of agonists and antagonists to the opiate receptor .

HY-D0975

Sulfo-SMCC sodium 5 Publications Verification	ADC Linker	Cancer
Sulfo-SMCC sodium is a commonly used hetero-bifunctional, noncleavable ADC crosslinker bearing N-hydroxysuccinimide (NHS) ester and maleimide groups to react with primary amines and sulfhydryl groups, respectively.

HY-42360

SMCC 1 Publications Verification	ADC Linker	Cancer
SMCC is a protein crosslinker. SMCC contains an amine-reactive N-hydroxysuccinimide ester and a sulfhydryl-reactive maleimide group that can be used in the conjugation of proteins. SMCC-conjugated antigen coupled spleen cells to induce antigen-specific immune responses .

HY-141540

Lactyl-CoA 4 Publications Verification	Biochemical Assay Reagents Endogenous Metabolite	Others
Lactyl-CoA is an acyl-CoA formally condensed from the sulfhydryl group of CoA and the carboxyl group of lactic acid, also known as lactyl-CoA. Lactyl-CoA is essential for the biosynthesis of biodegradable and biocompatible lactic acid-based copolymers .

HY-135233

N-Succinimidyl-S-acetylthioacetate SATA	Biochemical Assay Reagents	Others
N-Succinimidyl S-acetylthioacetate (SATA) is a protein modifying agent. N-Succinimidyl S-acetylthioacetate adds sulfhydryl groups to proteins and other amine-containing molecules in a protected form. N-Succinimidyl-S-acetylthioacetate can thiolate antibodies, thereby promoting efficient attachment of antibodies to other molecules and exerting conjugation activity. N-Succinimidyl-S-acetylthioacetate can be used in immunoassays such as ELISA studies .

HY-D1730

AF488 NHS ester 1 Publications Verification	Fluorescent Dye	Others
AF488 NHS ester is an amine specific fluorescence probe (Em=525 nm). AF488 NHS ester reacts with sulfhydryl groups and amines in aqueous and biological samples then change their chemical structure and fluorescence properties after derivatization .

HY-78961

6-Maleimidohexanoic acid N-hydroxysuccinimide ester EMCS	ADC Linker	Cancer
6-Maleimidohexanoic acid N-hydroxysuccinimide ester (EMCS) is a heterobifunctional cross-linking reagent. EMCS is used as a unique and useful reagent for preparation of hapten conjugate and enzyme immunoconjugates .

HY-W020780

mPEG5000-Mal mPEG5000-Maleimide	Biochemical Assay Reagents	Cancer
mPEG5000-Mal (mPEG5000-Maleimide) is a PEG-derived selective covalent binding agent for sulfhydryl groups (RSGs), which can form irreversible thioether bonds with sulfhydryl groups under near-neutral conditions via the maleimide group. The mechanism of action of mPEG5000-Mal can be divided into two categories: firstly, as an enzyme modifier, it binds to target proteins through hydrophobic interactions, hydrogen bonds, and van der Waals forces, altering the protein's secondary structure; secondly, as a nanoparticle surface modifier, it covalently binds to sulfhydryl groups on the surface of red blood cells, changing the surface properties and morphology of the red blood cells, leading to their phagocytosis by macrophages of the reticuloendothelial system. mPEG5000-Mal can react with free cysteine in proteins, increasing the apparent molecular weight of the modified protein by 10-15 kDa for detection purposes. mPEG5000-Mal can enhance the thermal stability and catalytic activity of enzymes, and improve the macrophage targeting of nanoparticles, enabling targeted drug delivery. mPEG5000-Mal can be applied in enzyme engineering research in the food industry and in oncology, assisting radiotherapy by inhibiting tumor-associated macrophage infiltration and enhancing anti-tumor immune responses .

HY-100216

SPDP 5 Publications Verification SPDP Crosslinker; Py-ds-Prp-OSu	ADC Linker	Cancer
SPDP (SPDP Crosslinker) is a short-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls. It is a glutathione cleavable ADC linker used for the antibody-drug conjugates (ADCs) .

HY-Y1666

2,2′-Dipyridyl disulfide	Biochemical Assay Reagents	Others
2,2′-Dipyridyl disulfide is a useful reagent for the determination of sulfhydryl groups. 2,2′-Dipyridyl disulfide is a common reagent in peptide chemistry, often used in oxidation–reduction condensations to form peptide bonds or in coupling reactions to form disulfide-linked heterodimers .

HY-128925

AMAS 1 Publications Verification	ADC Linker	Cancer
AMAS is a nonclaevable heterobifunctional crosslinker with NHS ester and maleimide groups that allows covalent conjugation of amine- and sulfhydryl-containing molecules.

HY-119970

Helenalin 5+ Cited Publications	NF-κB	Inflammation/Immunology Cancer
Helenalin is an anti-inflammatory sesquiterpene lactone. Helenalin selectively inhibits transcription factor NF-κB by directly targeting p65. Helenalin has alkylating activity, targets the cysteine sulfhydryl groups in the p65 subunit of NF-κB, thereby inhibits its DNA binding .

HY-D0843S

N-Ethylmaleimide-d5 NEM-d₅	Cathepsin Deubiquitinase	Others
N-Ethylmaleimide-d₅ is the deuterium labeled N-Ethylmaleimide. N-Ethylmaleimide (NEM), a reagent that alkylates free sulfhydryl groups, is a cysteine protease inhibitor . N-ethylmaleimide specific inhibits phosphate transport in mitochondria . N-Ethylmaleimide is also a deubiquitinating enzyme inhibitor .

HY-121167

L-Albizziin 1 Publications Verification	Glutaminase	Cancer
L-albizziin, as a sulfhydryl group reagent, is a glutamase inhibitor. L-albizziin can be used for the research of cancer .

HY-W041994

GMBS	Fructose-1,6-bisphosphate aldolase Biochemical Assay Reagents	Cancer
GMBS is a heterobifunctional crosslinker targeting primary amines and sulfhydryl groups. GMBS can be used for chemical crosslinking of proteins and crosslinking mass spectrometry (CXMS) to study protein folding and map interfaces between interacting proteins .

HY-Y0102

Thiosalicylic acid 2-Mercaptobenzoic acid	Biochemical Assay Reagents Drug Intermediate	Infection
Thiosalicylic acid (2-Mercaptobenzoic acid) is an organosulfur compound bearing both sulfhydryl and carboxyl functional groups. Thiosalicylic acid acts as a desulfurizing agent. Thiosalicylic acid also serves as a ligand to synthesize azosulfonamide derivatives with antibacterial and antifungal activities, as well as their Fe ³⁺, Cu ²⁺ and Hg ²⁺ chelates .

HY-N6773

Cytochalasin A	HIV Protease Fungal	Infection
Cytochalasin A is a cell-permeable fungal toxin that is an oxidized derivative of cytochalasin B. Cytochalasin A is an inhibitor of HIV-1 protease (IC₅₀=3 μM) and inhibits actin polymerization and interferes with microtubule assembly by reacting with sulfhydryl groups. Antibiotic and fungicidal activitives .

HY-174921A

Maleimide-PEG2000-COOH	Biochemical Assay Reagents	Others
Maleimide-PEG2000-COOH is a PEG derivative composed of Maleimide (HY-W007324), PEG units and carboxyl (-COOH). Carboxyl can easily form a stable amide bond with amino groups or an ester bond with hydroxyl groups. Maleimide forms a stable thioether bond with sulfhydryl (-SH) .

HY-E70364

IgdE protease	Biochemical Assay Reagents	Inflammation/Immunology
IgdE protease is a cysteine protease, which is initially isolated from Streptococcus agalactiae. IgdE protease digests monoclonal antibodies (mAbs) of the IgG1 type specifically at their upper hinge region, produces Fc/2, hinge peptide dimers, and Fab fragment. IgdE protease can be used in disulfide bonds and free thiol analysis, as it requires no reducing agents for cleavage .

HY-W1048849B

4-Arm PEG-SH (MW 10000) 4-Arm PEG-thiol (MW 10000)	Biochemical Assay Reagents	Others
4-Arm PEG-SH (MW 10000) (4-Arm PEG-thiol (MW 10000)) is a multi-arm PEG derivative with thiol groups at each end of the four arms. The reactive free thiol, SH or sulfhydryl groups react selectively with maleimide and transition metal surfaces including gold and silver .

HY-D1260

FM-red PSH-red	Fluorescent Dye	Neurological Disease
FM-red (PSH-red) is a red-emitting and environment-sensitive probe for selectively detecting and labeling protein thiols. FM-red can be used to image protein sulfhydryl groups in live cells and in vivo. FM-red also could be used to measure of the redox states of thioredoxin (Trx) .

HY-W1048553A

Mal-PEG2000-NH2 TFA	Biochemical Assay Reagents	Others
Mal-PEG2000-NH2TFA is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .

HY-120128

MTSEA hydrobromide	Biochemical Assay Reagents	Neurological Disease
MTSEA hydrobromide is a sulfhydryl-reactive compound that modifies free cysteine residues to produce a positively charged side chain approximately the size of lysine .

HY-N16290

Chol-PEG2000 maleimide	Biochemical Assay Reagents	Others
Chol-PEG2000-maleimide is a PEG derivative composed of Cholesterol, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .

HY-129654

MTSES sodium Sodium (2-Sulfonatoethyl)methanethiosulfonate	Biochemical Assay Reagents	Others
MTSES sodium (Sodium (2-Sulfonatoethyl)methanethiosulfonate) is a negatively charged, membrane-impermeable methanethiosulfonate (MTS). MTS is a compound that reacts with sulfhydryl groups to form mixed disulfide bonds and is often used to study cysteine ??residues on proteins.

HY-D2798

FITC-PEG400-SH	Fluorescent Dye	Others
FITC-PEG400-SH is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a sulfhydryl (SH). FITC-PEG400-SH can be used for fluorescent labeling and imaging .

HY-D1565

Cy7.5 maleimide 1 Publications Verification	Fluorescent Dye	Others
Cy7.5 maleimide is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .

HY-137791

MMBC	Fluorescent Dye	Others
MMBC is a sulfhydryl-sensitive fluorophore .

HY-W1048553B

Mal-PEG3400-NH2 TFA 1 Publications Verification	Biochemical Assay Reagents	Others
Mal-PEG3400-NH2TFA is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .

HY-W1048553C

Mal-PEG5000-NH2 TFA	Biochemical Assay Reagents	Others
Mal-PEG5000-NH2TFA is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .

HY-164785

TCO-PEG5-C2-Mal	Drug Intermediate	Others
TCO-PEG5-maleimide is a PEG linker with TCO and maleimide groups, specifically enabling tetrazine click chemistry and thiol conjugation for bioconjugation, probe design, and drug delivery.

HY-W273281

6,6′-Dithiodinicotinic acid	MOFs	Others
6,6′-Dithiodinicotinic acid is a sulfur-containing organic compound belonging to nicotinic acid derivatives, which can be used as a specific sulfhydryl blocker .

HY-D1869

800CW maleimide	Fluorescent Dye	Others
800CW maleimide is an infrared dye that can be used for labeling molecules that contain free sulfhydryl (–SH) groups (Ex: 778 nm; Em: 796 nm). 800CW maleimide binds to plasma proteins .

HY-174953A

TPP-PEG2000-Mal	Biochemical Assay Reagents	Others
TPP-PEG2000-Mal is a PEG derivative composed of triphenyl phosphate (TPP), PEG units, and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .

HY-174953B

TPP-PEG3400-Mal	Biochemical Assay Reagents	Others
TPP-PEG3400-Mal is a PEG derivative composed of triphenyl phosphate (TPP), PEG units, and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .

HY-W190755

Mal-PEG4-mal	Biochemical Assay Reagents	Others
Mal-PEG4-Mal is a PEG derivative with maleimide groups at both ends. Maleimide is a functional group that can undergo Michael addition reactions with sulfhydryl groups (–SH) and can be used for bioconjugation .

HY-D2798B

FITC-PEG5000-SH	Fluorescent Dye	Others
FITC-PEG5000-SH is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a sulfhydryl (SH). FITC-PEG5000-SH can be used for fluorescent labeling and imaging .

HY-D2182

Preactivated PE-Cy5 Maleimide	Fluorescent Dye	Others
Preactivated PE-Cy5 Maleimide is a sulfhydryl reactive dye that reacts with free sulfhydryl groups on proteins. Preactivated APC-Cy5.5 Maleimide binds easily to proteins or antibodies, and does not change the spectral characteristics of APC-Cy/YF after activation.

HY-W1048553

Mal-PEG1000-NH2 TFA	Biochemical Assay Reagents	Others
Mal-PEG1000-NH2TFA is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .

HY-D2180

Preactivated APC-Cy5.5 Maleimide	Fluorescent Dye	Others
Preactivated APC-Cy5.5 Maleimide is a sulfhydryl reactive dye that reacts with free sulfhydryl groups on proteins. Preactivated APC-Cy5.5 Maleimide binds easily to proteins or antibodies, and does not change the spectral characteristics of APC-Cy/YF after activation.

HY-160926

16-Oxocafestol	Glutathione S-transferase	Cancer
16-Oxocafestol enhances levels of glutathione S-transferase (GST) and tissue sulfhydryl in liver and in small bowel mucosa .

HY-W1048555B

Mal-PEG3400-SCM	Biochemical Assay Reagents	Others
Mal-PEG3400-SCM is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG3400-SCM is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .

HY-129655

Sulfo-SMPB sodium	ADC Linker	Cancer
Sulfo-SMPB sodium is a non-cleavable, heterobifunctional chemical cross-linking reagent which contains N-hydroxysuccinimide (NHS) ester and maleimide groups, allowing covalent conjugation of amine- and sulfhydryl-containing molecules .

HY-W440718C

Cholesterol-PEG10000-Mal	Biochemical Assay Reagents	Others
Cholesterol-PEG10000-Mal is a PEG derivative composed of Cholesterol, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .

HY-D0843R

N-Ethylmaleimide (Standard) NEM (Standard)	Reference Standards Cathepsin Deubiquitinase Apoptosis	Others
Bayogenin (Standard) is the analytical standard of Bayogenin. This product is intended for research and analytical applications. Bayogenin is an alfalfa saponin, shows moderate potency of glycogen phosphorylase inhibition .

HY-174953

TPP-PEG1000-Mal	Biochemical Assay Reagents	Others
TPP-PEG1000-Mal is a PEG derivative composed of triphenyl phosphate (TPP), PEG units, and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .

HY-W101609

Phenylethyl isovalerate	Cholinesterase (ChE)	Others
Phenylethyl isovalerate is a synthetic flavoring substance with very low acute oral toxicity. Phenylethyl isovalerate after long-term low-dose intake increases the activity of alanine aminotransferase (ALT) and the level of sulfhydryl groups in the serum, but decreases the activity of cholinesterase (ChE) .

HY-D0152

Tetramethylrhodamine-6-maleimide	Fluorescent Dye	Others
Tetramethylrhodamine-6-maleimide is a fluorescent dye with a reactive sulfhydryl-specific moiety is covalently coupled to this cysteine. Tetramethylrhodamine-6-maleimide can be used as labels to detect local protein motions of the fully active Na+/K+-ATPase in real time .

HY-W588728

DBCO-PEG8-amine	Biochemical Assay Reagents	Others
DBCO-PEG8-amine is a PEG derivative consisting of DBCO, PEG units and an amino group (Amine). Maleimide forms a stable thioether bond with sulfhydryl (-SH). The amino group can react with other chemical groups (such as carboxyl, aldehyde, etc.) to form stable chemical bonds.

Cat. No.	Product Name	Type

HY-66019

FITC

Maximum Cited Publications

92 Publications Verification

Fluorescein 5-isothiocyanate

Fluorescent Dyes

FITC (Fluorescein Isothiocyanate), is one of the green fluorescein derivatives widely used in biology. FITC has the characteristics of high absorptivity and excellent fluorescence quantum yield. The isothiocyanate group of FITC can be combined with amino, sulfhydryl, imidazole, tyrosyl, carbonyl and other groups on the protein, so as to achieve protein labeling including antibodies and lectins. In addition to its use as a protein marker, FITC can also be used as a fluorescent protein tracer to rapidly identify pathogens by labeling antibodies, or for microsequencing of proteins and peptides (HPLC). The maximum excitation wavelength of FITC is 494 nm. Once excited, it fluoresces yellow-green at a maximum emission wavelength of 520 nm. In addition, FITC is also a hapten that can induce contact hypersensitivity (CHS) and induce an atopic dermatitis model .

HY-D1730A

AF488 NHS ester TEA 1 Publications Verification	Fluorescent Dyes
AF488 NHS ester TEA is an amine specific fluorescence probe (λ_em=525 nm=525 nm). AF488 NHS ester reacts with sulfhydryl groups and amines in aqueous and biological samples then change their chemical structure and fluorescence properties after derivatization. AF488 exhibits the λ_em and λ_ex wavelength of 520 nm and 470 nm, respectively .

HY-DY1007

FITC (solution)

Fluorescent Dyes

FITC (Fluorescein Isothiocyanate) (solution) , is one of the green fluorescein derivatives widely used in biology. FITC has the characteristics of high absorptivity and excellent fluorescence quantum yield. The isothiocyanate group of FITC can be combined with amino, sulfhydryl, imidazole, tyrosyl, carbonyl and other groups on the protein, so as to achieve protein labeling including antibodies and lectins. In addition to its use as a protein marker, FITC can also be used as a fluorescent protein tracer to rapidly identify pathogens by labeling antibodies, or for microsequencing of proteins and peptides (HPLC). The maximum excitation wavelength of FITC is 494 nm. Once excited, it fluoresces yellow-green at a maximum emission wavelength of 520 nm. In addition, FITC is also a hapten that can induce contact hypersensitivity (CHS) and induce an atopic dermatitis model .
Solvent and concentration: DMSO: 20 mM
The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.

HY-W998680

Fluorescein-maleimide

5-FITC-Maleimide

Fluorescent Dyes

Fluorescein-maleimide (5-FITC-Maleimide) is a thiol-reactive fluorescent derivatization reagent and non-specific protein labeling reagent. Fluorescein-maleimide covalently binds to protein thiol groups for protein labeling. Fluorescein-maleimide covalently binds to protein amino and imidazole groups under neutral pH conditions. Fluorescein-maleimide is used for fluorescent labeling of proteins, nucleic acids or other molecules containing one or more thiol groups (Ex/Em = 494/519 nm) .

HY-D1260

FM-red PSH-red	Fluorescent Dyes
FM-red (PSH-red) is a red-emitting and environment-sensitive probe for selectively detecting and labeling protein thiols. FM-red can be used to image protein sulfhydryl groups in live cells and in vivo. FM-red also could be used to measure of the redox states of thioredoxin (Trx) .

HY-D2798

FITC-PEG400-SH	Fluorescent Dyes
FITC-PEG400-SH is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a sulfhydryl (SH). FITC-PEG400-SH can be used for fluorescent labeling and imaging .

HY-D1565

Cy7.5 maleimide

1 Publications Verification

Fluorescent Dyes

Cy7.5 maleimide is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .

HY-D2529

Cy5-PEG2000-SH	Fluorescent Dyes
Cy5-PEG2000-SH is a fluorescent labeling reagent that combines Cy5 (HY-D0821) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.

HY-D2448

Cy3-PEG-Thiol	Fluorescent Dyes
Cy3-PEG-Thiol (Cy3-PEG-SH) is a near infrared fluorescent labeling reagent that combines Cy3 fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) polyethylene glycol derivatives, and is suitable for molecular coupling. Cy3-PEG-Thiol is absorbed at 550nm and has high solubility and end-group substitution rate .

HY-D1869

800CW maleimide	Fluorescent Dyes
800CW maleimide is an infrared dye that can be used for labeling molecules that contain free sulfhydryl (–SH) groups (Ex: 778 nm; Em: 796 nm). 800CW maleimide binds to plasma proteins .

HY-D2798B

FITC-PEG5000-SH	Fluorescent Dyes
FITC-PEG5000-SH is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a sulfhydryl (SH). FITC-PEG5000-SH can be used for fluorescent labeling and imaging .

HY-D2531

Cy5-PEG5000-SH	Fluorescent Dyes
Cy5-PEG5000-SH is a fluorescent labeling reagent that combines Cy5 (HY-D0821) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.

HY-D2556

Cy5.5-PEG1000-SH	Fluorescent Dyes
Cy5.5-PEG1000-SH is a fluorescent labeling reagent that combines Cy5.5 (HY-D0924) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.

HY-D2182

Preactivated PE-Cy5 Maleimide	Fluorescent Dyes
Preactivated PE-Cy5 Maleimide is a sulfhydryl reactive dye that reacts with free sulfhydryl groups on proteins. Preactivated APC-Cy5.5 Maleimide binds easily to proteins or antibodies, and does not change the spectral characteristics of APC-Cy/YF after activation.

HY-D2180

Preactivated APC-Cy5.5 Maleimide	Fluorescent Dyes
Preactivated APC-Cy5.5 Maleimide is a sulfhydryl reactive dye that reacts with free sulfhydryl groups on proteins. Preactivated APC-Cy5.5 Maleimide binds easily to proteins or antibodies, and does not change the spectral characteristics of APC-Cy/YF after activation.

HY-D0152

Tetramethylrhodamine-6-maleimide	Fluorescent Dyes
Tetramethylrhodamine-6-maleimide is a fluorescent dye with a reactive sulfhydryl-specific moiety is covalently coupled to this cysteine. Tetramethylrhodamine-6-maleimide can be used as labels to detect local protein motions of the fully active Na+/K+-ATPase in real time .

HY-D2532

Cy5-PEG10000-SH	Fluorescent Dyes
Cy5-PEG10000-SH is a fluorescent labeling reagent that combines Cy5 (HY-D0821) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.

HY-D2589

Cy7.5 PEG-SH	Fluorescent Dyes
Cy7.5 PEG-SH is a fluorescent labeling reagent that combines CY7.5 (HY-D0926) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds (Ex/Em = 770/820 nm).

HY-D2510

Cy3-PEG2000-SH	Fluorescent Dyes
Cy3-PEG2000-SH (Cy3-PEG-Thiol) is a near infrared fluorescent labeling reagent that combines Cy3 fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) polyethylene glycol derivatives, and is suitable for molecular coupling. Cy3-PEG2000-SH is absorbed at 550nm and has high solubility and end-group substitution rate .

HY-D1618

Cyanine3 maleimide tetrafluoroborate	Fluorescent Dyes
Cyanine3 maleimide tetrafluoroborate is a specific labeling reagent for sulfhydryl groups with the λ_ex of 550 nm and λ_em of 580 nm. Cyanine3 maleimide tetrafluoroborate can be used for protein and peptide labeling .

HY-D2094

PerCP Maleimide	Fluorescent Dyes
PerCP Maleimide is a fluorescent dye that reacts with free sulfhydryl groups on proteins. PerCP is a red fluorescence albuminous dye for immunostaining and Maleimide can be leveraged for the preparation of fluorogenic probe, which is mainly used for the specific detection of thiol analytes .

HY-D2798A

FITC-PEG1000-SH	Fluorescent Dyes
FITC-PEG1000-SH is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a sulfhydryl (SH). FITC-PEG1000-SH can be used for fluorescent labeling and imaging .

HY-D2883E

RB-PEG5000-SH Rhodamine B-PEG5000-SH	Fluorescent Dyes
RB-PEG5000-SH (Rhodamine B-PEG5000-SH) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and sulfhydryl (SH). SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds (Ex/Em=546/610 nm) .

HY-D2883D

RB-PEG3400-SH Rhodamine B-PEG3400-SH	Fluorescent Dyes
RB-PEG3400-SH (Rhodamine B-PEG3400-SH) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and sulfhydryl (SH). SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds (Ex/Em=546/610 nm) .

HY-D2509

Cy3-PEG1000-SH	Fluorescent Dyes
Cy3-PEG1000-SH is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds .

HY-D2883

RB-PEG400-SH Rhodamine B-PEG400-SH	Fluorescent Dyes
RB-PEG400-SH (Rhodamine B-PEG400-SH) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and sulfhydryl (SH). SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds (Ex/Em=546/610 nm) .

HY-D2513

Cy3-PEG10000-SH	Fluorescent Dyes
Cy3-PEG10000-SH (Cy3-PEG-Thiol) is a near infrared fluorescent labeling reagent that combines Cy3 fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) polyethylene glycol derivatives, and is suitable for molecular coupling. Cy3-PEG10000-SH is absorbed at 550nm and has high solubility and end-group substitution rate .

HY-D2511

Cy3-PEG3400-SH	Fluorescent Dyes
Cy3-PEG3400-SH (Cy3-PEG-Thiol) is a near infrared fluorescent labeling reagent that combines Cy3 fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) polyethylene glycol derivatives, and is suitable for molecular coupling. Cy3-PEG3400-SH is absorbed at 550nm and has high solubility and end-group substitution rate .

HY-D2798C

FITC-PEG10000-SH	Fluorescent Dyes
FITC-PEG10000-SH is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a sulfhydryl (SH). FITC-PEG10000-SH can be used for fluorescent labeling and imaging .

HY-D3291

IR 680LT Maleimide	Fluorescent Dyes
IR 680LT Maleimide is a near-infrared low-band fluorescence dye, composed of the IR 680LT dye core and maleimide groups. IR 680LT Maleimide is used for specifically labeling biologically active molecules containing sulfhydryl groups (Ex/Em = 679 nm/694 nm).

HY-D2763

BP Fluor 532 maleimide

Fluorescent Dyes

BP Fluor 532 maleimide is a photostable, bright yellow-fluorescent dye with pH insensitive emission from pH 4 to pH 10. The excitation of BP Fluor 532 is ideally suited for the frequency-doubled Nd:YAG laser line. BP Fluor 532 dye can be conjugated to a variety of antibodies, peptides, proteins, tracers, and amplification substrates, and is often used for the generation of stable signals in imaging and flow cytometry. Maleimide is the most popular sulfhydryl-reactive group for conjugating the dye to a thiol group on a protein, oligonucleotide thiophosphate, or low molecular weight ligand. The maleimide group specifically and efficiently reacts with reduced thiols (sulfhydryl groups, –SH) at pH 6.5 to 7.5 to form a stable thioether bond. The resulting conjugates exhibit brighter fluorescence and greater photostability than the conjugates of many other spectrally similar fluorophores.

HY-D2530

Cy5-PEG3400-SH	Fluorescent Dyes
Cy5-PEG3400-SH is a fluorescent labeling reagent that combines Cy5 (HY-D0821) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.

HY-D2883B

RB-PEG1000-SH Rhodamine B-PEG1000-SH	Fluorescent Dyes
RB-PEG1000-SH (Rhodamine B-PEG1000-SH) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and sulfhydryl (SH). SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds (Ex/Em=546/610 nm) .

HY-D2883C

RB-PEG2000-SH Rhodamine B-PEG2000-SH	Fluorescent Dyes
RB-PEG2000-SH (Rhodamine B-PEG2000-SH) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and sulfhydryl (SH). SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds (Ex/Em=546/610 nm) .

HY-D2883H

RB-PEG10000-SH Rhodamine B-PEG10000-SH	Fluorescent Dyes
RB-PEG10000-SH (Rhodamine B-PEG10000-SH) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and sulfhydryl (SH). SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds (Ex/Em=546/610 nm) .

HY-D2883A

RB-PEG600-SH Rhodamine B-PEG600-SH	Fluorescent Dyes
RB-PEG600-SH (Rhodamine B-PEG600-SH) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and sulfhydryl (SH). SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds (Ex/Em=546/610 nm) .

HY-D2512

Cy3-PEG5000-SH	Fluorescent Dyes
Cy3-PEG5000-SH is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds .

HY-D2557

Cy5.5-PEG3400-SH	Fluorescent Dyes
Cy5.5-PEG3400-SH is a fluorescent labeling reagent that combines Cy5.5 (HY-D0924) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.

HY-D2559

Cy5.5-PEG10000-SH	Fluorescent Dyes
Cy5.5-PEG10000-SH is a fluorescent labeling reagent that combines Cy5.5 (HY-D0924) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.

HY-D2558

Cy5.5-PEG5000-SH	Fluorescent Dyes
Cy5.5-PEG5000-SH is a fluorescent labeling reagent that combines Cy5.5 (HY-D0924) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.

HY-42360G

SMCC

Fluorescent Dyes

SMCC (GMP) is the GMP level of SMCC (HY-42360). GMP guidelines are used to produce SMCC (HY-42360) (GMP). GMP small molecules works appropriately as an auxiliary reagent for cell research manufacture. SMCC (GMP) is a protein crosslinker. SMCC (GMP) contains an amine-reactive N-hydroxysuccinimide ester and a sulfhydryl-reactive maleimide group that can be used in the conjugation of proteins. SMCC-conjugated antigen coupled spleen cells to induce antigen-specific immune responses.

Cat. No.	Product Name	Type

HY-148905

p-Aminophenylmercuric acetate

Maximum Cited Publications

10 Publications Verification

Biochemical Assay Reagents

p-Aminophenylmercuric acetate is an organomercurial activator of matrix metalloproteinases (MMP). P-Aminophenylmercuric acetate participates in the activation and inhibition of MMP-8 by attacking protein sulfhydryl or inducing cysteine switching reaction. p-Aminophenylmercuric acetate promotes the shedding of betacellulin precursor (pro-BTC). p-Aminophenylmercuric acetate influences the binding of agonists and antagonists to the opiate receptor .

HY-D0975

Sulfo-SMCC sodium 5 Publications Verification	Biochemical Assay Reagents
Sulfo-SMCC sodium is a commonly used hetero-bifunctional, noncleavable ADC crosslinker bearing N-hydroxysuccinimide (NHS) ester and maleimide groups to react with primary amines and sulfhydryl groups, respectively.

HY-140739

DSPE-PEG2000-Maleimide sodium (purity>95%)

2 Publications Verification

Biochemical Assay Reagents

DSPE-PEG2000-Maleimide sodium (purity>95%) is a phospholipid-PEG conjugate. DSPE-PEG2000-Maleimide utilizes the amphiphilicity of DSPE to insert into the lipid bilayer of liposomes or nanoparticles. DSPE-PEG2000-Maleimide covalently couples to the sulfhydryl (-SH) of ligands (such as antibodies, peptides, or proteins) via thiol-maleimide click chemistry, giving the particles targeting capabilities. DSPE-PEG2000-Maleimide sodium (purity>95%) can be used in the researches of breast cancer, lymphoma, and inherited retinal degeneration .

HY-135233

N-Succinimidyl-S-acetylthioacetate

SATA

Biochemical Assay Reagents

N-Succinimidyl S-acetylthioacetate (SATA) is a protein modifying agent. N-Succinimidyl S-acetylthioacetate adds sulfhydryl groups to proteins and other amine-containing molecules in a protected form. N-Succinimidyl-S-acetylthioacetate can thiolate antibodies, thereby promoting efficient attachment of antibodies to other molecules and exerting conjugation activity. N-Succinimidyl-S-acetylthioacetate can be used in immunoassays such as ELISA studies .

HY-W020780

mPEG5000-Mal

mPEG5000-Maleimide

Biochemical Assay Reagents

mPEG5000-Mal (mPEG5000-Maleimide) is a PEG-derived selective covalent binding agent for sulfhydryl groups (RSGs), which can form irreversible thioether bonds with sulfhydryl groups under near-neutral conditions via the maleimide group. The mechanism of action of mPEG5000-Mal can be divided into two categories: firstly, as an enzyme modifier, it binds to target proteins through hydrophobic interactions, hydrogen bonds, and van der Waals forces, altering the protein's secondary structure; secondly, as a nanoparticle surface modifier, it covalently binds to sulfhydryl groups on the surface of red blood cells, changing the surface properties and morphology of the red blood cells, leading to their phagocytosis by macrophages of the reticuloendothelial system. mPEG5000-Mal can react with free cysteine in proteins, increasing the apparent molecular weight of the modified protein by 10-15 kDa for detection purposes. mPEG5000-Mal can enhance the thermal stability and catalytic activity of enzymes, and improve the macrophage targeting of nanoparticles, enabling targeted drug delivery. mPEG5000-Mal can be applied in enzyme engineering research in the food industry and in oncology, assisting radiotherapy by inhibiting tumor-associated macrophage infiltration and enhancing anti-tumor immune responses .

HY-15917A

L-Dithiothreitol

2 Publications Verification

Biochemical Assay Reagents

L-Dithiothreitol (DTT) is a reducing agent commonly used in various biochemical applications to break disulfide bonds in proteins, thereby denaturing proteins or preventing the formation of unwanted aggregates. DTT has a unique chemical property that cleaves the sulfur-sulfur bond in the disulfide bond to form a sulfhydryl group. This makes it a useful tool for protein purification, enzyme assays, and protein structure studies.

HY-Y0102

Thiosalicylic acid 2-Mercaptobenzoic acid	Biochemical Assay Reagents
Thiosalicylic acid (2-Mercaptobenzoic acid) is an organosulfur compound bearing both sulfhydryl and carboxyl functional groups. Thiosalicylic acid acts as a desulfurizing agent. Thiosalicylic acid also serves as a ligand to synthesize azosulfonamide derivatives with antibacterial and antifungal activities, as well as their Fe ³⁺, Cu ²⁺ and Hg ²⁺ chelates .

HY-174921A

Maleimide-PEG2000-COOH	Biochemical Assay Reagents
Maleimide-PEG2000-COOH is a PEG derivative composed of Maleimide (HY-W007324), PEG units and carboxyl (-COOH). Carboxyl can easily form a stable amide bond with amino groups or an ester bond with hydroxyl groups. Maleimide forms a stable thioether bond with sulfhydryl (-SH) .

HY-77961

6-Maleimidocaproic acid hydrazide TFA N-ε-Maleimidocaproic acid hydrazide TFA	Biochemical Assay Reagents
6-Maleimidocaproic acid hydrazide TFA is a carbonyl and sulfhydryl reactive heterobifunctional crosslinking reagent .

HY-W1048849B

4-Arm PEG-SH (MW 10000) 4-Arm PEG-thiol (MW 10000)	Biochemical Assay Reagents
4-Arm PEG-SH (MW 10000) (4-Arm PEG-thiol (MW 10000)) is a multi-arm PEG derivative with thiol groups at each end of the four arms. The reactive free thiol, SH or sulfhydryl groups react selectively with maleimide and transition metal surfaces including gold and silver .

HY-W1048849A

4-Arm PEG5000-SH 4-Arm PEG5000-thiol	Biochemical Assay Reagents
4-Arm PEG5000-SH (4-Arm PEG5000-thiol) is a multi-arm PEG derivative with thiol groups at each end of the four arms. The reactive free thiol, SH or sulfhydryl groups react selectively with maleimide and transition metal surfaces including gold and silver .

HY-W1048553A

Mal-PEG2000-NH2 TFA	Biochemical Assay Reagents
Mal-PEG2000-NH2TFA is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .

HY-W1048849C

4-Arm PEG20000-SH 4-Arm PEG20000-thiol	Biochemical Assay Reagents
4-Arm PEG20000-SH (4-Arm PEG20000-thiol) is a multi-arm PEG derivative with thiol groups at each end of the four arms. The reactive free thiol, SH or sulfhydryl groups react selectively with maleimide and transition metal surfaces including gold and silver .

HY-W1048553B

Mal-PEG3400-NH2 TFA 1 Publications Verification	Biochemical Assay Reagents
Mal-PEG3400-NH2TFA is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .

HY-W1048553C

Mal-PEG5000-NH2 TFA	Biochemical Assay Reagents
Mal-PEG5000-NH2TFA is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .

HY-174953A

TPP-PEG2000-Mal	Biochemical Assay Reagents
TPP-PEG2000-Mal is a PEG derivative composed of triphenyl phosphate (TPP), PEG units, and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .

HY-174953B

TPP-PEG3400-Mal	Biochemical Assay Reagents
TPP-PEG3400-Mal is a PEG derivative composed of triphenyl phosphate (TPP), PEG units, and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .

HY-W190755

Mal-PEG4-mal	Biochemical Assay Reagents
Mal-PEG4-Mal is a PEG derivative with maleimide groups at both ends. Maleimide is a functional group that can undergo Michael addition reactions with sulfhydryl groups (–SH) and can be used for bioconjugation .

HY-W879049

DBCO-PEG3-Maleimide DBCO-NHCO-PEG3-maleimide	Biochemical Assay Reagents
DBCO-PEG3-Maleimide is a PEG derivative consisting of DBCO, PEG units, and Maleimide (HY-W007324). NMaleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG3-Maleimide contains a DBCO group, which can undergo a strain-promoted alkyne-azide cycloaddition reaction (SPAAC) with molecules containing an azide group .

HY-W1048553

Mal-PEG1000-NH2 TFA	Biochemical Assay Reagents
Mal-PEG1000-NH2TFA is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .

HY-W1048555B

Mal-PEG3400-SCM

Biochemical Assay Reagents

Mal-PEG3400-SCM is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG3400-SCM is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .

HY-W440718C

Cholesterol-PEG10000-Mal	Biochemical Assay Reagents
Cholesterol-PEG10000-Mal is a PEG derivative composed of Cholesterol, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .

HY-174953

TPP-PEG1000-Mal	Biochemical Assay Reagents
TPP-PEG1000-Mal is a PEG derivative composed of triphenyl phosphate (TPP), PEG units, and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .

HY-W588728

DBCO-PEG8-amine	Biochemical Assay Reagents
DBCO-PEG8-amine is a PEG derivative consisting of DBCO, PEG units and an amino group (Amine). Maleimide forms a stable thioether bond with sulfhydryl (-SH). The amino group can react with other chemical groups (such as carboxyl, aldehyde, etc.) to form stable chemical bonds.

HY-157920

Biotin-PE-maleimide N-Biotinyl-N'-[2-(N-maleimido)ethyl]piperazine	Biochemical Assay Reagents
Biotin-PE-maleimide (N-Biotinyl-N'-[2-(N-maleimido)ethyl]piperazine) is a bulky, membrane-impermeable, sulfhydryl-containing reagent with a relatively large molecular size. Biotin-PE-maleimide can be used for biotin labeling (such as thiol groups) and detection of proteins or other biomolecules .

HY-167036C

DMG-PEG5000-Mal	Biochemical Assay Reagents
DMG-PEG5000-Mal is a PEG derivative composed of N,N-Dimethylglycine (DMG), PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DMG-PEG5000-Mal can be used for drug delivery .

HY-W591465

4-Arm-PEG2000-Maleimide 4-Arm-PEG2000-Mal	Biochemical Assay Reagents
4-Arm-PEG2000-Maleimide (4-Arm-PEG2000-Mal) is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .

HY-W1048849D

4-Arm PEG40000-SH 4-Arm PEG40000-thiol	Biochemical Assay Reagents
4-Arm PEG40000-SH (4-Arm PEG40000-thiol) is a multi-arm PEG derivative with thiol groups at each end of the four arms. The reactive free thiol, SH or sulfhydryl groups react selectively with maleimide and transition metal surfaces including gold and silver .

HY-W879036

DBCO-PEG8-Maleimide	Biochemical Assay Reagents
DBCO-PEG8-Maleimide is a PEG derivative consisting of DBCO, PEG units, and Maleimide (HY-W007324). NMaleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG8-Maleimide contains a DBCO group, which can undergo a strain-promoted alkyne-azide cycloaddition reaction (SPAAC) with molecules containing an azide group .

HY-174927E

DBCO-PEG3400-Maleimide DBCO-PEG3400-Mal	Biochemical Assay Reagents
DBCO-PEG3400-Maleimide (DBCO-PEG3400-Mal) is a PEG derivative composed of DBCO, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG3400-Maleimide contains a DBCO group and can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an azide group .

HY-174927B

DBCO-PEG600-Maleimide DBCO-PEG600-Mal	Biochemical Assay Reagents
DBCO-PEG600-Maleimide (DBCO-PEG600-Mal) is a PEG derivative composed of DBCO, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG600-Maleimide contains a DBCO group and can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an azide group .

HY-174927A

DBCO-PEG400-Maleimide DBCO-PEG400-Mal	Biochemical Assay Reagents
DBCO-PEG400-Maleimide (DBCO-PEG400-Mal) is a PEG derivative composed of DBCO, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG400-Maleimide contains a DBCO group and can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an azide group .

HY-174927D

DBCO-PEG2000-Maleimide DBCO-PEG2000-Mal	Biochemical Assay Reagents
DBCO-PEG2000-Maleimide (DBCO-PEG2000-Mal) is a PEG derivative composed of DBCO, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG2000-Maleimide contains a DBCO group and can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an azide group .

HY-174927H

DBCO-PEG10000-Maleimide DBCO-PEG10000-Mal	Biochemical Assay Reagents
DBCO-PEG10000-Maleimide (DBCO-PEG10000-Mal) is a PEG derivative composed of DBCO, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG10000-Maleimide contains a DBCO group and can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an azide group .

HY-W1048545H

H2N-PEG1000-SH hydrochloride Amine-PEG1000-Thiol hydrochloride	Biochemical Assay Reagents
H2N-PEG1000-SH (Amine-PEG1000-Thiol) hydrochloride is a linear heterobifunctional PEGylated product containing thiol and amine. H2N-PEG1000-SH hydrochloride is an important cross-linking or bioconjugation reagent with PEG chains. Thiol or SH, sulfhydryl or thiol selectively reacts with maleimide, OPSS, vinyl sulfone and transition metal surfaces (including gold, silver, etc.) .

HY-W1048553H

Mal-PEG40000-NH2 TFA	Biochemical Assay Reagents
Mal-PEG40000-NH2TFA is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .

HY-W1048553E

Mal-PEG20000-NH2 TFA	Biochemical Assay Reagents
Mal-PEG20000-NH2TFA is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .

HY-W1048553D

Mal-PEG10000-NH2 TFA	Biochemical Assay Reagents
Mal-PEG10000-NH2TFA is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .

HY-W698574

Dansylamidoethyl mercaptan	Biochemical Assay Reagents
Dansylamidoethyl mercaptan is a molecule that reacts with -SH groups of proteins and other sulfhydryl-containing molecules and has activity for detecting SS bonds in proteins.

HY-W1048555D

Mal-PEG10000-SCM

Biochemical Assay Reagents

Mal-PEG10000-SCM is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG10000-SCM is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .

HY-W1048555

Mal-PEG1000-SCM

Biochemical Assay Reagents

Mal-PEG1000-SCM is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG1000-SCM is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .

HY-W190746

Mal-PEG1-Mal	Biochemical Assay Reagents
Mal-PEG1-Mal is a PEG derivative with maleimide groups at both ends. Maleimide is a functional group that can undergo Michael addition reactions with sulfhydryl groups (–SH) and can be used for bioconjugation .

HY-W588736

DBCO-PEG23-amine	Biochemical Assay Reagents
DBCO-PEG23-amine is a PEG derivative consisting of DBCO, PEG units and an amino group (Amine). Maleimide forms a stable thioether bond with sulfhydryl (-SH). The amino group can react with other chemical groups (such as carboxyl, aldehyde, etc.) to form stable chemical bonds.

HY-174921B

Maleimide-PEG3400-COOH	Biochemical Assay Reagents
Maleimide-PEG3400-COOH is a PEG derivative composed of Maleimide (HY-W007324), PEG units and carboxyl (-COOH). Carboxyl can easily form a stable amide bond with amino groups or an ester bond with hydroxyl groups. Maleimide forms a stable thioether bond with sulfhydryl (-SH) .

HY-174921C

Maleimide-PEG5000-COOH	Biochemical Assay Reagents
Maleimide-PEG5000-COOH is a PEG derivative composed of Maleimide (HY-W007324), PEG units and carboxyl (-COOH). Carboxyl can easily form a stable amide bond with amino groups or an ester bond with hydroxyl groups. Maleimide forms a stable thioether bond with sulfhydryl (-SH) .

HY-174921

Maleimide-PEG1000-COOH	Biochemical Assay Reagents
Maleimide-PEG1000-COOH is a PEG derivative composed of Maleimide (HY-W007324), PEG units and carboxyl (-COOH). Carboxyl can easily form a stable amide bond with amino groups or an ester bond with hydroxyl groups. Maleimide forms a stable thioether bond with sulfhydryl (-SH) .

HY-167036A

DMG-PEG1000-Mal	Biochemical Assay Reagents
DMG-PEG1000-Mal is a PEG derivative composed of N,N-Dimethylglycine (DMG), PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DMG-PEG1000-Mal can be used for drug delivery .

HY-W591618D

4-Arm-PEG3400-Maleimide 4-Arm-PEG3400-Mal	Biochemical Assay Reagents
4-Arm-PEG3400-Maleimide (4-Arm-PEG3400-Mal) is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .

HY-W591618A

4-Arm-PEG400-Maleimide 4-Arm-PEG400-Mal	Biochemical Assay Reagents
4-Arm-PEG400-Maleimide (4-Arm-PEG400-Mal) is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .

HY-W591618C

4-Arm-PEG1000-Maleimide 4-Arm-PEG1000-Mal	Biochemical Assay Reagents
4-Arm-PEG1000-Maleimide (4-Arm-PEG1000-Mal) is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .

Cat. No.	Product Name	Target	Research Area

HY-P1801

Cys-TAT(47-57) Cys-[HIV-Tat (47-57)]	HIV Drug Derivative	Others
Cys-TAT(47-57) (Cys-[HIV-Tat (47-57)]), TAT (HY-P0281) derivative, is a Cysteine (HY-Y0337)-tagged cell-penetrating peptide (CPP) derived from the HIV TAT protein. Cys-TAT(47-57) can be used for the research for the research of drug delivery .

Cat. No.	Product Name

HY-K0219

High-Affinity Iodoacetyl Agarose 1 Publications Verification
MCE High-Affinity Iodoacetyl Agarose, a 4% highly cross-linked agarose reagent coupled with a derivative of iodoacetic acid, is ideal for conjugating sulfhydryl-containing peptide or protein for subsequent affinity purification.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-D0843

N-Ethylmaleimide 35+ Cited Publications NEM	Microorganisms Source Classification	Cathepsin Deubiquitinase Apoptosis
N-Ethylmaleimide (NEM) derives from maleic acid, it can alkylates free sulfhydryl. N-Ethylmaleimide is an irreversible cysteine protease inhibitor. N-ethylmaleimide specific inhibits phosphate transport in mitochondria. N-Ethylmaleimide inhibits prolyl endopeptidase with an IC₅₀ value of 6.3 μM. N-Ethylmaleimide can be used to modify cysteine residues in proteins and peptides .

HY-119970

Helenalin 5+ Cited Publications	other families Classification of Application Fields Terpenoids Sesquiterpenes Plants Inflammation/Immunology Disease Research Fields Source Classification	NF-κB
Helenalin is an anti-inflammatory sesquiterpene lactone. Helenalin selectively inhibits transcription factor NF-κB by directly targeting p65. Helenalin has alkylating activity, targets the cysteine sulfhydryl groups in the p65 subunit of NF-κB, thereby inhibits its DNA binding .

HY-N6773

Cytochalasin A	Infection Alkaloids Microorganisms Pyrrole Alkaloids Classification of Application Fields Disease Research Fields Source Classification	HIV Protease Fungal
Cytochalasin A is a cell-permeable fungal toxin that is an oxidized derivative of cytochalasin B. Cytochalasin A is an inhibitor of HIV-1 protease (IC₅₀=3 μM) and inhibits actin polymerization and interferes with microtubule assembly by reacting with sulfhydryl groups. Antibiotic and fungicidal activitives .

HY-N16290

Chol-PEG2000 maleimide	Lipid	Biochemical Assay Reagents
Chol-PEG2000-maleimide is a PEG derivative composed of Cholesterol, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .

HY-D0843R

N-Ethylmaleimide (Standard) NEM (Standard)	Microorganisms Source Classification	Reference Standards Cathepsin Deubiquitinase Apoptosis
Bayogenin (Standard) is the analytical standard of Bayogenin. This product is intended for research and analytical applications. Bayogenin is an alfalfa saponin, shows moderate potency of glycogen phosphorylase inhibition .

HY-W101609

Phenylethyl isovalerate	Michelia × alba DC. Structural Classification Natural Products Magnoliaceae Plants Source Classification	Cholinesterase (ChE)
Phenylethyl isovalerate is a synthetic flavoring substance with very low acute oral toxicity. Phenylethyl isovalerate after long-term low-dose intake increases the activity of alanine aminotransferase (ALT) and the level of sulfhydryl groups in the serum, but decreases the activity of cholinesterase (ChE) .

HY-N7594

Senecionine acetate O-Acetylsenecionine	Alkaloids Pyrrole Alkaloids Classification of Application Fields Erinacea anthyllis Link Other Diseases Plants Compositae Disease Research Fields Source Classification	Mitochondrial Metabolism
Senecionine acetate (O-Acetylsenecionine) is a pyrrolizidine alkaloid. Senecionine acetate inhibits the sequestration of Ca ²⁺ in extramitochondrial and mitochondrial compartments possibly by inactivating free sulfhydryl groups .

HY-N16237

Chol-PEG1000-maleimide	Lipid	Biochemical Assay Reagents
Chol-PEG1000-maleimide is a PEG derivative composed of Cholesterol, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .

HY-N11739

Helenalin isobutyrate	Centipeda minima (L.) A. Braun & Asch. Structural Classification Terpenoids Sesquiterpenes Plants Compositae Source Classification	NF-κB
Helenalin isobutyrate is an NF-κB (p65 subunit) inhibitor with anti-inflammatory activity. Helenalin isobutyrate irreversibly alkylates cysteine sulfhydryl groups in the p65 subunit to inhibit NF-κB complex DNA binding activity .

HY-N12639

β-Sanshool	Zanthoxylum bungeanum Maxim. Structural Classification Natural Products Rutaceae Plants Source Classification	TRP Channel
β-Sanshool is found in Zanthoxylum bungeanum and has a unique pungent taste. β-Sanshool is a TRPV1 activator that activates TRPV1 to increase intracellular calcium concentration. β-Sanshool has antioxidant effects and enhances free radical scavenging activity. β-Sanshool increases the thermal denaturation temperature and stabilizes protein structures. β-Sanshool induces sensory experiences of numbness and bitterness .

HY-N19808

2-Deacetyl-4-tigloylchamissionolide	Structural Classification Terpenoids Sesquiterpenes Plants Compositae Source Classification	Drug Derivative
2-Deacetyl-4-tigloylchamissionolide is a heliangolide-type sesquiterpene lactone, a derivative of Chamissonolide (HY-N19727), and a cytotoxic agent. 2-Deacetyl-4-tigloylchamissionolide exerts cytotoxicity via alkylating biological nucleophiles, targeting free thiol groups in proteins to interfere with their functions. 2-Deacetyl-4-tigloylchamissionolide exhibits different chromatographic behaviors in TLC and HPLC. 2-Deacetyl-4-tigloylchamissionolide can be used for the research of Ehrlich ascites carcinoma .

Cat. No.	Product Name	Chemical Structure

HY-D0843S

N-Ethylmaleimide-d5
N-Ethylmaleimide-d₅ is the deuterium labeled N-Ethylmaleimide. N-Ethylmaleimide (NEM), a reagent that alkylates free sulfhydryl groups, is a cysteine protease inhibitor . N-ethylmaleimide specific inhibits phosphate transport in mitochondria . N-Ethylmaleimide is also a deubiquitinating enzyme inhibitor .

HY-117281S

Moexipril-d5
Moexipril-d₅ is the deuterium labeled Moexipril. Moexipril hydrochloride is a potent orally active non-sulfhydryl angiotensin converting enzyme(ACE) inhibitor, which is used for the treatment of hypertension and congestive heart failure .

HY-141540S1

Lactyl-CoA-d3
Lactyl-CoA-d₃ is the deuterium labeled Lactyl-CoA (HY-141540). Lactyl-CoA is an acyl-CoA formally condensed from the sulfhydryl group of CoA and the carboxyl group of lactic acid, also known as lactyl-CoA. Lactyl-CoA is essential for the biosynthesis of biodegradable and biocompatible lactic acid-based copolymers.

Cat. No.	Product Name		Classification

HY-W879049

DBCO-PEG3-Maleimide DBCO-NHCO-PEG3-maleimide		DBCO
DBCO-PEG3-Maleimide is a PEG derivative consisting of DBCO, PEG units, and Maleimide (HY-W007324). NMaleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG3-Maleimide contains a DBCO group, which can undergo a strain-promoted alkyne-azide cycloaddition reaction (SPAAC) with molecules containing an azide group .

HY-W588728

DBCO-PEG8-amine		DBCO
DBCO-PEG8-amine is a PEG derivative consisting of DBCO, PEG units and an amino group (Amine). Maleimide forms a stable thioether bond with sulfhydryl (-SH). The amino group can react with other chemical groups (such as carboxyl, aldehyde, etc.) to form stable chemical bonds.

HY-W879036

DBCO-PEG8-Maleimide		DBCO
DBCO-PEG8-Maleimide is a PEG derivative consisting of DBCO, PEG units, and Maleimide (HY-W007324). NMaleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG8-Maleimide contains a DBCO group, which can undergo a strain-promoted alkyne-azide cycloaddition reaction (SPAAC) with molecules containing an azide group .

HY-174927E

DBCO-PEG3400-Maleimide DBCO-PEG3400-Mal		DBCO
DBCO-PEG3400-Maleimide (DBCO-PEG3400-Mal) is a PEG derivative composed of DBCO, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG3400-Maleimide contains a DBCO group and can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an azide group .

HY-174927B

DBCO-PEG600-Maleimide DBCO-PEG600-Mal		DBCO
DBCO-PEG600-Maleimide (DBCO-PEG600-Mal) is a PEG derivative composed of DBCO, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG600-Maleimide contains a DBCO group and can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an azide group .

HY-174927A

DBCO-PEG400-Maleimide DBCO-PEG400-Mal		DBCO
DBCO-PEG400-Maleimide (DBCO-PEG400-Mal) is a PEG derivative composed of DBCO, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG400-Maleimide contains a DBCO group and can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an azide group .

HY-174927D

DBCO-PEG2000-Maleimide DBCO-PEG2000-Mal		DBCO
DBCO-PEG2000-Maleimide (DBCO-PEG2000-Mal) is a PEG derivative composed of DBCO, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG2000-Maleimide contains a DBCO group and can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an azide group .

HY-174927H

DBCO-PEG10000-Maleimide DBCO-PEG10000-Mal		DBCO
DBCO-PEG10000-Maleimide (DBCO-PEG10000-Mal) is a PEG derivative composed of DBCO, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG10000-Maleimide contains a DBCO group and can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an azide group .

HY-W588736

DBCO-PEG23-amine		DBCO
DBCO-PEG23-amine is a PEG derivative consisting of DBCO, PEG units and an amino group (Amine). Maleimide forms a stable thioether bond with sulfhydryl (-SH). The amino group can react with other chemical groups (such as carboxyl, aldehyde, etc.) to form stable chemical bonds.

HY-174927

DBCO-PEG5000-Maleimide DBCO-PEG5000-Mal		DBCO
DBCO-PEG5000-Maleimide (DBCO-PEG5000-Mal) is a PEG derivative composed of DBCO, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG5000-Maleimide contains a DBCO group and can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an azide group .

HY-174927C

DBCO-PEG1000-Maleimide DBCO-PEG1000-Mal		DBCO
DBCO-PEG1000-Maleimide (DBCO-PEG1000-Mal) is a PEG derivative composed of DBCO, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG1000-Maleimide contains a DBCO group and can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an azide group .

Cat. No.	Product Name		Classification

HY-140739

DSPE-PEG2000-Maleimide sodium (purity>95%) 2 Publications Verification		Pegylated Lipids
DSPE-PEG2000-Maleimide sodium (purity>95%) is a phospholipid-PEG conjugate. DSPE-PEG2000-Maleimide utilizes the amphiphilicity of DSPE to insert into the lipid bilayer of liposomes or nanoparticles. DSPE-PEG2000-Maleimide covalently couples to the sulfhydryl (-SH) of ligands (such as antibodies, peptides, or proteins) via thiol-maleimide click chemistry, giving the particles targeting capabilities. DSPE-PEG2000-Maleimide sodium (purity>95%) can be used in the researches of breast cancer, lymphoma, and inherited retinal degeneration .

HY-W440718C

Cholesterol-PEG10000-Mal		Pegylated Lipids
Cholesterol-PEG10000-Mal is a PEG derivative composed of Cholesterol, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .

HY-167036C

DMG-PEG5000-Mal		Pegylated Lipids
DMG-PEG5000-Mal is a PEG derivative composed of N,N-Dimethylglycine (DMG), PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DMG-PEG5000-Mal can be used for drug delivery .

HY-140739A

DSPE-PEG2000-Maleimide free acid		Pegylated Lipids
DSPE-PEG2000-Maleimide free acid is a phospholipid-PEG conjugate. DSPE-PEG2000-Maleimide free acid utilizes the amphiphilicity of DSPE to insert into the lipid bilayer of liposomes or nanoparticles. DSPE-PEG2000-Maleimide free acid covalently couples to the sulfhydryl (-SH) of ligands (such as antibodies, peptides, or proteins) via thiol-maleimide click chemistry, giving the particles targeting capabilities. DSPE-PEG2000-Maleimide free acid can be used in the researches of breast cancer, lymphoma, and inherited retinal degeneration .

HY-167036A

DMG-PEG1000-Mal		Pegylated Lipids
DMG-PEG1000-Mal is a PEG derivative composed of N,N-Dimethylglycine (DMG), PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DMG-PEG1000-Mal can be used for drug delivery .

HY-167036D

DMG-PEG10000-Mal		Pegylated Lipids
DMG-PEG10000-Mal is a PEG derivative composed of N,N-Dimethylglycine (DMG), PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DMG-PEG10000-Mal can be used for drug delivery .

HY-167036B

DMG-PEG3400-Mal		Pegylated Lipids
DMG-PEG3400-Mal is a PEG derivative composed of N,N-Dimethylglycine (DMG), PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DMG-PEG3400-Mal can be used for drug delivery .

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-42360G

SMCC	ADC Linker	Inflammation/Immunology Cancer
SMCC (GMP) is the GMP level of SMCC (HY-42360). GMP guidelines are used to produce SMCC (HY-42360) (GMP). GMP small molecules works appropriately as an auxiliary reagent for cell research manufacture. SMCC (GMP) is a protein crosslinker. SMCC (GMP) contains an amine-reactive N-hydroxysuccinimide ester and a sulfhydryl-reactive maleimide group that can be used in the conjugation of proteins. SMCC-conjugated antigen coupled spleen cells to induce antigen-specific immune responses.

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