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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
syntenin
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "syntenin" in MCE Product Catalog:
Synonyms: 113B7
PDZ1i (113B7) is a inhibitor of MDA-9/Syntenin, with selective binding to the PDZ1 domain. PDZ1i inhibits radiation-induced invasion of glioblastoma (GBM) cells, radiosensitizes GBM cells, and impairs GBM-related signaling pathways (including Src/EphA2, EGFRvIII/FAK, and NF-κB). PDZ1i reduces radiation-induced secretion of invasion-related proteases (MMP-2, MMP-9, ADAM9). PDZ1i shows anti-tumor effects in nude mice bearing intracranial U1242-luc xenografts or GBM xenografts. PDZ1i can be used for the study of glioblastoma (GBM), breast cancer and prostate cancer .
Cat. No.: HY-P10331
CAS No.: 2757292-12-7
Cat. No.: HY-156247
IVMT-Rx-3 is a inhibitor of SDCBP targeting of the PDZ1 and PDZ2 Domains of MDA-9/Syntenin. IVMT-Rx-3 blocks MDA-9/Syntenin interaction with Src, reduces NF-κB activation, and inhibits MMP-2/MMP-9 expression. IVMT-Rx-3 inhibits Melanoma Metastasis [1]
Cat. No.: HY-162510
SPDZi1 is a potent and selective syntenin inhibitor that binds to PDZ1 and PDZ2 domains of syntenin. SPDZi1 binds to the syntenin PDZ tandem (STNPDZ) with a Kd of 3.6 μM. SPDZi1 suppresses glioblastoma and reduces the activation of NF-κB, a downstream effector of syntenin .
Cat. No.: HY-P85539
Synonyms: MDA-9; MDA9; Melanoma differentiation-associated protein 9; Pro-TGF-alpha cytoplasmic domain-interacting protein 18; Scaffold protein Pbp1; SDCB1_HUMAN; Sdcbp; SDCBP; ST1; SYCL; Syndecan binding protein; syntenin; Syndecan binding protein 1; Syndecan-binding protein 1; syntenin 1; syntenin-1; TACIP18.
Cat. No.: HY-P71014
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SDCBP; TACIP18; Syndecan Binding Protein; MDA9; MDA-9; CDNA FLJ55055, Moderately Similar To syntenin-1; SYCL; Melanoma Differentiation Associated Protein-9; syntenin-1; Melanoma Differentiation-Associated Protein 9; SDCBP1; Syndecan Binding Protein (Synte
Species:
Human
Source:
E. coli
Cat. No.: HY-P71014A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SDCBP; TACIP18; Syndecan Binding Protein; MDA9; MDA-9; CDNA FLJ55055, Moderately Similar To syntenin-1; SYCL; Melanoma Differentiation Associated Protein-9; syntenin-1; Melanoma Differentiation-Associated Protein 9; SDCBP1; Syndecan Binding Protein (Synte
Species:
Human
Source:
E. coli
Cat. No.: HY-P81310A
Synonyms: SDCBP; MDA9; SYCL; syntenin-1; Melanoma differentiation-associated protein 9; MDA-9; Pro-TGF-alpha cytoplasmic domain-interacting protein 18; TACIP18; Scaffold protein Pbp1; Syndecan-binding protein 1
Cat. No.: HY-174601
Target:
Research Areas:
Human IL5RA mRNA encodes the human interleukin 5 receptor subunit alpha (IL5RA) protein, an interleukin 5 specific subunit of a heterodimeric cytokine receptor. IL5RA has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
