KSL 128114
Based on 1 publication(s) in Google Scholar
KSL 128114, a peptide inhibitor of syntenin, binds the PDZ1 domain of syntenin with nanomolar affinity. KSL 128114 is resistant toward degradation in human plasma and mouse hepatic microsomes and displays a global PDZ domain selectivity for syntenin.
For research use only. We do not sell to patients.
- CAS No.: 2757292-12-7
- Formula: C96H165N39O21
- Molecular Weight:2201.59
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
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Publications Citing Use of MedChemExpress (MCE) KSL 128114
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Biological Activity
KSL-128114 (~20 μM) shows an inhibitory effect on primary GBM cell viability and significantly extends survival time in a patient-derived xenograft mouse model[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2757292-12-7
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Molecular Weight 2201.59
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Formula C96H165N39O21
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Sequence
Ac-{d-Arg}-Arg-{d-Arg}-Gly-{d-Arg}-Lys-{d-Lys}-Arg-{d-Arg}-Ser-His-Trp-{Tle}-{Chg}-Asp-Ile
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Sequence Shortening
Ac-{d-Arg}-R-{d-Arg}-G-{d-Arg}-K-{d-Lys}-R-{d-Arg}-SHW-{Tle}-{Chg}-DI
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
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Eur J Med Chem
Design, synthesis, and biological evaluation of novel and highly potent peptides targeting syntenin. [Abstract]2025 May 5:289:117446. PMID: 40020425
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
KSL 128114 Related Classifications
HY-P10331 Related Classifications
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