4 Results for "

systemic arterial pressure

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "systemic arterial pressure" in MCE Product Catalog:

Cat. No.: HY-P3765
CAS No.: 91421-87-3
Target:  

Inhibitory Antibodies

Research Areas:  

Cardiovascular Disease

Auriculin A is a synthetic atrial natriuretic factor (ANF) with hemodynamic effect. Auriculin A antagonizes renal vasoconstriction in the dog, and influences on arterial baroreflex control of heart rate, systemic blood pressure, and perfusion pressure in the hind limb (perfused at constant flow) in rabbits .
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Cat. No.: HY-118765
CAS No.: 110996-51-5
Research Areas:  

Cardiovascular Disease

Ro 23-3423 is a thromboxane synthase inhibitor with an IC50 value of 0.33 μM for human platelet microsomal thromboxane synthase. Ro 23-3423 increases plasma levels of PGF and PGE2 in a dose-dependent manner, accompanied by a decrease in mean systemic arterial pressure and systemic vascular resistance. Ro 23-3423 can be used in the study of general anesthesia .
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Cat. No.: HY-105925
CAS No.: 58261-91-9
Synonyms: MCN 2378
Target:  

Adrenergic Receptor

Research Areas:  

Cardiovascular Disease

Mefenidil (MCN 2378) is a selective cerebral vasodilator that is not affected by beta-adrenergic blockade. Mefenidil can be used in the study of cardiovascular disease. In monkey models, mefenidil preferentially increases cerebral blood flow over systemic (femoral) blood flow. Mefenidil is also able to reduce systemic arterial pressure in anesthetized dogs.
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Cat. No.: HY-P992358

Target:  

ADAMTS

Research Areas:  

Cardiovascular Disease

GSK2394002 is an antibody inhibitor targeting ADAMTS-4 and ADAMTS-5, with cartilage-penetrating ability following systemic administration. GSK2394002 inhibits the release of aggrecan-derived neoepitopes and reduces cartilage degradation, exhibiting the potential to relieve pain, alleviate hyperalgesia and inhibit the progression of joint damage. GSK2394002 also induces potentially irreversible cardiovascular effects such as increased mean arterial pressure and myocardial ischemia in cynomolgus monkeys .
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