110996-51-5
Chemical Structure
Ro 23-3423
- CAS No.: 110996-51-5
- Formula:C23H22N4O2
- Molecular Weight:386.45
IUPAC Name: 1-oxo-N-(5-(pyridin-3-yl)pentan-2-yl)-1H-pyrido[2,1-b]quinazoline-8-carboxamide
InChIKey: XGWLCZMAVDFGQE-UHFFFAOYSA-N
SMILES: O=C(NC(CCCC1=CC=CN=C1)C)C2=CN(C(C=C2)=N3)C=C4C3=CC=CC4=O
Biological Activity: Ro 23-3423 is a thromboxane synthase inhibitor with an IC50 value of 0.33 μM for human platelet microsomal thromboxane synthase. Ro 23-3423 increases plasma levels of PGF and PGE2 in a dose-dependent manner, accompanied by a decrease in mean systemic arterial pressure and systemic vascular resistance. Ro 23-3423 can be used in the study of general anesthesia[1].
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Ro 23-3423 | Ro 23-3423 is a thromboxane synthase inhibitor with an IC50 value of 0.33 μM for human platelet microsomal thromboxane synthase. Ro 23-3423 increases plasma levels of PGF and PGE2 in a dose-dependent manner, accompanied by a decrease in mean systemic arterial pressure and systemic vascular resistance. Ro 23-3423 can be used in the study of general anesthesia. | |||||||||||||||||||||
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