58261-91-9
Chemical Structure
Mefenidil
Synonym(s): MCN 2378
- CAS No.: 58261-91-9
- Formula:C12H11N3
- Molecular Weight:197.24
IUPAC Name: 2-(4-methyl-2-phenyl-1H-imidazol-5-yl)acetonitrile
InChIKey: OTRQRKIYHATFKM-UHFFFAOYSA-N
SMILES: N#CCC1=C(C)N=C(C2=CC=CC=C2)N1
Biological Activity: Mefenidil (MCN 2378) is a selective cerebral vasodilator that is not affected by beta-adrenergic blockade. Mefenidil can be used in the study of cardiovascular disease. In monkey models, mefenidil preferentially increases cerebral blood flow over systemic (femoral) blood flow. Mefenidil is also able to reduce systemic arterial pressure in anesthetized dogs.
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Mefenidil | Mefenidil (MCN 2378) is a selective cerebral vasodilator that is not affected by beta-adrenergic blockade. Mefenidil can be used in the study of cardiovascular disease. In monkey models, mefenidil preferentially increases cerebral blood flow over systemic (femoral) blood flow. Mefenidil is also able to reduce systemic arterial pressure in anesthetized dogs. | |||||||||||||||||||||
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Keywords
