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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
18 Results for "
terfenadine
" in MedChemExpress (MCE) Product Catalog:
Products (18)
18 Results for "terfenadine" in MCE Product Catalog:
4
Research Areas:
Terfenadine ((±)-Terfenadine) is a potent open-channel blocker of hERG with an IC50 of 204 nM . Terfenadine, an H1 histamine receptor antagonist, acts as a potent apoptosis inducer in melanoma cells through modulation of Ca 2+ homeostasis. Terfenadine induces ROS-dependent apoptosis, simultaneously activates Caspase-4, -2, -9 .
5
5 Cited Publications
Cat. No.: HY-B0801
CAS No.: 83799-24-0
Synonyms: MDL-16455; terfenadine carboxylate
Target:
Research Areas:
Fexofenadine (MDL-16455) is an orally active and nonsedative H1 receptor antagonist. Fexofenadine can be used in allergic rhinitis and chronic idiopathic urticarial research .
5
5 Cited Publications
Cat. No.: HY-B0801A
CAS No.: 153439-40-8
Synonyms: MDL-16455 hydrochloride; terfenadine carboxylate hydrochloride
Target:
Research Areas:
Fexofenadine (MDL-16455) hydrochloride is an orally active and nonsedative H1 receptor antagonist. Fexofenadine hydrochloride can be used in allergic rhinitis and chronic idiopathic urticarial research .
2
2 Cited Publications
Cat. No.: HY-B0801S
CAS No.: 548783-71-7
Synonyms: MDL-16455-d6; terfenadine carboxylate-d6
1
Target:
Research Areas:
Azacyclonol (γ-pipradol), a metabolite of Terfenadine, is a central depressant agent. Azacyclonol is a ganglion-blocking agent. Azacyclonol can be used to diminish psychoses-induced hallucinations .
1
1 Cited Publications
Target:
Research Areas:
LKY-047, a Decursin derivative, is a potent and selective reversible competitive cytochrome P45022J2 (CYP2J2) inhibitor with an IC50 of 1.7 μM. LKY-047 is inactive against other human P450s, such as CYPs 1A2, 2A6, 2B6, 2C8, 2C9, 2C19, 2D6, 2E1, and 3A .
Synonyms: meta-MDL-16455; meta-terfenadine carboxylate
Target:
Research Areas:
meta-Fexofenadine (meta-MDL-16455) is an impurity of Fexofenadine . Fexofenadine, a H1R antagonist, is an anti-allergic agent used in seasonal allergic rhinitis and chronic idiopathic urticarial .
Cat. No.: HY-B1193R
CAS No.: 50679-08-8
Synonyms: (±)-terfenadine (Standard); MDL-991 (Standard)
Target:
Reference Standards Potassium Channel Histamine Receptor Na+/Ca2+ Exchanger Caspase Apoptosis
Research Areas:
Terfenadine (Standard) is the analytical standard of Terfenadine. This product is intended for research and analytical applications. Terfenadine ((±)-Terfenadine) is a potent open-channel blocker of hERG with an IC50 of 204 nM . Terfenadine, an H1 histamine receptor antagonist, acts as a potent apoptosis inducer in melanoma cells through modulation of Ca2+ homeostasis. Terfenadine induces ROS-dependent apoptosis, simultaneously activates Caspase-4, -2, -9 .
Cat. No.: HY-B0801AR
CAS No.: 153439-40-8
Synonyms: MDL-16455 hydrochloride (Standard); terfenadine carboxylate hydrochloride (Standard)
Research Areas:
Fexofenadine (hydrochloride) (Standard) is the analytical standard of Fexofenadine (hydrochloride). This product is intended for research and analytical applications. Fexofenadine (MDL-16455) hydrochloride is an orally active and nonsedative H1 receptor antagonist. Fexofenadine hydrochloride can be used in allergic rhinitis and chronic idiopathic urticarial research .
Cat. No.: HY-B0801R
CAS No.: 83799-24-0
Synonyms: MDL-16455 (Standard); terfenadine carboxylate (Standard)
Research Areas:
Fexofenadine (Standard) is the analytical standard of Fexofenadine. This product is intended for research and analytical applications. Fexofenadine (MDL-16455) is an orally active and nonsedative H1 receptor antagonist. Fexofenadine can be used in allergic rhinitis and chronic idiopathic urticarial research .
Cat. No.: HY-B1193S
CAS No.: 192584-82-0
Research Areas:
Azacyclonol (Standard) is the analytical standard of Azacyclonol. This product is intended for research and analytical applications. Azacyclonol (γ-pipradol), a metabolite of Terfenadine, is a central depressant agent. Azacyclonol is a ganglion-blocking agent. Azacyclonol can be used to diminish psychoses-induced hallucinations .
Cat. No.: HY-B0801AS
CAS No.: 1215821-44-5
Synonyms: MDL-16455-d10 hydrochloride; terfenadine carboxylate-d10 hydrochloride
Cat. No.: HY-100657R
CAS No.: 479035-75-1
Synonyms: meta-MDL-16455 (Standard); meta-terfenadine carboxylate (Standard)
Target:
Research Areas:
meta-Fexofenadine (Standard) is the analytical standard of meta-Fexofenadine. This product is intended for research and analytical applications. meta-Fexofenadine (meta-MDL-16455) is an impurity of Fexofenadine . Fexofenadine, a H1R antagonist, is an anti-allergic agent used in seasonal allergic rhinitis and chronic idiopathic urticarial .
Cat. No.: HY-B0801S2
Synonyms: MDL-16455-d3; terfenadine carboxylate-d3
Cat. No.: HY-B0801S4
Synonyms: MDL-16455-d3-1; terfenadine carboxylate-d3-1
Cat. No.: HY-100657S
Synonyms: meta-MDL-16455-d6; meta-terfenadine carboxylate-d6
Cat. No.: HY-133727
CAS No.: 634901-83-0
Target:
Research Areas:
Terfenadine N-oxide, an N-oxide derivative of Terfenadine (HY-B1193), is a histamine H1 receptor antagonist (IC50 = 2.73 μM) and an hERG potassium channel inhibitor (IC50 = 0.698 μM). Terfenadine N-oxide is can be used for the research of histamine-related allergic diseases and hERG channel-associated arrhythmias .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
