83799-24-0
83799-24-0
Chemical Structure
Fexofenadine
Synonym(s): MDL-16455; Terfenadine carboxylate
- CAS No.: 83799-24-0
- Formula:C32H39NO4
- Molecular Weight:501.66
IUPAC Name: 2-(4-(1-hydroxy-4-(4-(hydroxydiphenylmethyl)piperidin-1-yl)butyl)phenyl)-2-methylpropanoic acid
InChIKey: RWTNPBWLLIMQHL-UHFFFAOYSA-N
SMILES: OC(C1=CC=CC=C1)(C2=CC=CC=C2)C3CCN(CCCC(C4=CC=C(C(C(O)=O)(C)C)C=C4)O)CC3
Biological Activity: Fexofenadine (MDL-16455) is an orally active and nonsedative H1 receptor antagonist. Fexofenadine can be used in allergic rhinitis and chronic idiopathic urticarial research[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Fexofenadine | 99.96% | Fexofenadine (MDL-16455) is an orally active and nonsedative H1 receptor antagonist. Fexofenadine can be used in allergic rhinitis and chronic idiopathic urticarial research. | ||||||||||||||||||||
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Fexofenadine (Standard) | ≥98% | Fexofenadine (Standard) is the analytical standard of Fexofenadine. This product is intended for research and analytical applications. Fexofenadine (MDL-16455) is an orally active and nonsedative H1 receptor antagonist. Fexofenadine can be used in allergic rhinitis and chronic idiopathic urticarial research. | ||||||||||||||||||||
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Fexofenadine-d10 | Fexofenadine-d10 is deuterium labeled Fexofenadine. | |||||||||||||||||||||
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Fexofenadine-d6 | 99.28% | Fexofenadine-d6 (MDL-16455-d6) is deuterium labeled Fexofenadine, which is an antihistamine pharmaceutical agent. | ||||||||||||||||||||
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Fexofenadine-d3 | Fexofenadine-d3 is the deuterium labeled Fexofenadine. Fexofenadine (MDL-16455) is an orally active and nonsedative H1 receptor antagonist. Fexofenadine can be used in allergic rhinitis and chronic idiopathic urticarial research. | |||||||||||||||||||||
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Fexofenadine-d3-1 | Fexofenadine-d3-1 fumarate is deuterated labeled Fexofenadine (HY-B0801). Fexofenadine (MDL-16455) is an orally active and nonsedative H1 receptor antagonist. Fexofenadine can be used in allergic rhinitis and chronic idiopathic urticarial research. | |||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.99
HY-B0801AFexofenadine hydrochloride -
Similarity Score 0.92
HY-B0801S1Fexofenadine-d6 Methyl Ester -
Similarity Score 0.88
HY-131274Fexofenadine Impurity F -
Similarity Score 0.88
HY-100657Rmeta-Fexofenadine (Standard) -
Similarity Score 0.87
HY-B1193RTerfenadine (Standard) -
Similarity Score 0.81
HY-B0801ARFexofenadine hydrochloride (Standard) -
Similarity Score 0.76
HY-133727Terfenadine N-oxide -
Similarity Score 0.75
HY-100657meta-Fexofenadine -
Similarity Score 0.68
HY-B1193STerfenadine-d3 -
Explore the MedChemAI to find more analogs
References
- [1]. Watanabe N, et al. The effects of fexofenadine on eosinophilia and systemic anaphylaxis in mice infected with Trichinella spiralis. Int Immunopharmacol. 2004 Mar;4(3):367-75. [Content Brief]
- [2]. Park IH, et al. Histamine Promotes the Release of Interleukin-6 via the H1R/p38 and NF-κB Pathways in Nasal Fibroblasts. Allergy Asthma Immunol Res. 2014 Nov;6(6):567-72. [Content Brief]
- [3]. Ming X, et al. Vectorial transport of fexofenadine across Caco-2 cells: involvement of apical uptake and basolateral efflux transporters. Mol Pharm. 2011 Oct 3;8(5):1677-86. [Content Brief]
