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transgenic C. elegans

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

2

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B0512
    Sulfamerazine
    4 Publications Verification

    RP2632

    		 Antibiotic Bacterial α-synuclein Infection Neurological Disease
    Sulfamerazine (RP2632) is a brain-penetrant and orally active sulfonamide antibiotic and α-synuclein inhibitor with human α-synuclein KD of 352 μM. Sulfamerazine inhibits the synthesis of dihydrofolate by bacteria, thereby inhibiting bacterial growth. Sulfamerazine inhibits α-synuclein fibrillation, reduces α-synuclein aggregation-associated toxicity and α-synuclein aggregate accumulation. Sulfamerazine can be used for the research of Parkinson’s disease and bacterial infection .
    Sulfamerazine
  • HY-B0512R
    Sulfamerazine (Standard)

    RP2632 (Standard)

    		 Reference Standards Bacterial Antibiotic Infection
    Sulfamerazine (Standard) is the analytical standard of Sulfamerazine. This product is intended for research and analytical applications. Sulfamerazine (RP2632) is a brain-penetrant and orally active sulfonamide antibiotic and α-synuclein inhibitor with human α-synuclein KD of 352 μM. Sulfamerazine inhibits the synthesis of dihydrofolate by bacteria, thereby inhibiting bacterial growth. Sulfamerazine inhibits α-synuclein fibrillation, reduces α-synuclein aggregation-associated toxicity and α-synuclein aggregate accumulation. Sulfamerazine can be used for the research of Parkinson’s disease and bacterial infection .
    Sulfamerazine (Standard)
  • HY-B0512S1
    Sulfamerazine-13C6

    RP2632-13C6

    		 Isotope-Labeled Compounds Bacterial Antibiotic Infection
    Sulfamerazine- 13C6 (RP2632- 13C6) is 13C labeled Sulfamerazine (HY-B0512). Sulfamerazine (RP2632) is a brain-penetrant and orally active sulfonamide antibiotic and α-synuclein inhibitor with human α-synuclein KD of 352 μM. Sulfamerazine inhibits the synthesis of dihydrofolate by bacteria, thereby inhibiting bacterial growth. Sulfamerazine inhibits α-synuclein fibrillation, reduces α-synuclein aggregation-associated toxicity and α-synuclein aggregate accumulation. Sulfamerazine can be used for the research of Parkinson’s disease and bacterial infection .
    Sulfamerazine-13C6
  • HY-B0512S
    Sulfamerazine-d4

    RP2632-d4

    		 Isotope-Labeled Compounds Bacterial Infection
    Sulfamerazine-d4 is a deuterium labeled Sulfamerazine. Sulfamerazine (RP2632) is a brain-penetrant and orally active sulfonamide antibiotic and α-synuclein inhibitor with human α-synuclein KD of 352 μM. Sulfamerazine inhibits the synthesis of dihydrofolate by bacteria, thereby inhibiting bacterial growth. Sulfamerazine inhibits α-synuclein fibrillation, reduces α-synuclein aggregation-associated toxicity and α-synuclein aggregate accumulation. Sulfamerazine can be used for the research of Parkinson’s disease and bacterial infection .
    Sulfamerazine-d4
  • HY-116968
    JVW-1009

    		Sigma Receptor Neurological Disease
    JVW-1009 is a Sig2R/PGRMC1 antagonist (Sig1R Ki = 96 nM; Sig2R Ki = 70 nM). JVW-1009 acts as a neuroprotective agent. JVW-1009 can be used in the research of Alzheimer's disease .
    JVW-1009

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