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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
voltage imaging
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "voltage imaging" in MCE Product Catalog:
Cat. No.: HY-D3147
CAS No.: 1965316-23-7
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Research Areas:
RhoVR 1 is a voltage-sensitive probe targeted to the inner mitochondrial membrane. The detection mechanism of RhoVR 1 relies on membrane potential via the photoinduced electron transfer (PeT) mechanism. RhoVR 1 can be used for cell imaging .
Cat. No.: HY-D3445
CAS No.: 3029700-80-6
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JF629-HTL is a far-red fluorogenic HaloTag ligand. Binding of JF629-HTL to HaloTag protein alters the local environment of the dye, promoting the transition of rhodamine from a non-fluorescent state to a fluorescent state, thereby generating a fluorescence enhancement signal. In the light-controlled psHaloTag system, JF629-HTL shows a 6.7-fold fluorescence enhancement after irradiation at 450 nm. JF629-HTL serves as a research tool for far-red fluorescence imaging and the development of chemogenetic biosensors .
Cat. No.: HY-D3148
CAS No.: 1804107-88-7
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TPE-Ph-In is a mitochondria-targeted voltage-sensitive probe that can be used for mitochondrial membrane potential detection, mitochondrial imaging of animal and plant cells and tissues, mouse sperm activity indication, and detection of mitochondrial membrane potential changes associated with early apoptosis. TPE-Ph-In is non-fluorescent in solution, but emits strong fluorescence when aggregated via restriction of intramolecular rotation/movement, and its fluorescence intensity is directly correlated with local probe concentration or mitochondrial membrane potential level. TPE-Ph-In can penetrate cell membranes, target mitochondria through charge-dependent accumulation, has low cytotoxicity and high photostability, and enables super-resolution imaging of plant mitochondrial fission, fusion and cristae structures. The excitation wavelengths of TPE-Ph-In include 450 nm, 488 nm, and 489 nm, while its emission wavelengths include 551-661 nm, 660 nm, and 694 nm. TPE-Ph-In can be used for studies on mitochondrial dysfunction associated with early apoptosis .
Cat. No.: HY-D3146
CAS No.: 1418017-91-0
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Di-4-AN (F) EPPTEA is a voltage-sensitive dye used for membrane potential imaging and optical recording of electrical activity in excitable cells and tissues. Its detection mechanism is based on electrochromism (also known as the molecular Stark effect). The single-photon excitation/emission wavelengths measured in ethanol solution are Ex/Em = 444/610 nm, and it can be excited via 1064 nm two-photon excitation in optical recording applications. Di-4-AN (F) EPPTEA can be used to record backpropagating action potentials in individual dendritic spines of brain cortical slices, map subcellular action potential characteristics of single cardiomyocytes, and perform real-time recording of multicellular action potentials in cerebellar slices .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
