2 Results for "

wild-type P2X2 receptors

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "wild-type P2X2 receptors" in MCE Product Catalog:

Cat. No.: HY-W699451
MTSET chloride is a membrane-impermeable, thiol-specific reagent that primarily acts as an inhibitor of the Nav1.5 sodium channel. MTSET chloride reduces the peak sodium current amplitude of most mutant Nav1.5 channels, induces a hyperpolarizing shift in steady-state inactivation, and slows the recovery process, but shows no activity against wild-type and non-inactivating Nav1.5 channel mutants. MTSET chloride reacts covalently with T336C mutant P2X2 receptors, partially reversibly blocks ATP-induced cation currents, and exerts no effect on wild-type P2X2 receptors .
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Cat. No.: HY-189007
Target:  

P2X Receptor

Research Areas:  

Others

P2X2/3-antagonist-1 is a P2X2/3 purinergic receptor antagonist and taste blocker. P2X2/3-antagonist-1 binds to an allosteric site, induces a concentration-dependent rightward shift of the concentration-response curve of the α,β-Me-ATP agonist, and shares the binding site with AF-353 (HY-14483). P2X2/3-antagonist-1 blocks bitter taste perception in mice and abolishes their preference for plain water over bitter Quinine (HY-D0143) solution .
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