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Cat. No.: HY-137619A

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Sp-dCTPαS tetrasodium

Sp-dCTPαS tetrasodium is a sulfur-containing isomer of dGTP (HY-138616). Sp-dCTPαS tetrasodium inhibits SAMHD1 triphosphohydrolase activity with a K_i of 6.3 μM.

For research use only. We do not sell to patients.

Formula: C₉H₁₂N₃Na₄O₁₂P₃S
Molecular Weight:571.15

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

Sp-dCTPαS tetrasodium Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Sp-dCTPαS tetrasodium is a sulfur-containing isomer of dGTP (HY-138616). Sp-dCTPαS tetrasodium inhibits SAMHD1 triphosphohydrolase activity with a K_i of 6.3 μM^[1].

Chemical Information

Molecular Weight 571.15
Formula C₉H₁₂N₃Na₄O₁₂P₃S
SMILES

O[C@H]1C[C@H](N2C(N=C(N)C=C2)=O)O[C@@H]1CO[P@@](OP(OP(O[Na])(O[Na])=O)(O[Na])=O)(S[Na])=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Morris ER, et al. Probing the Catalytic Mechanism and Inhibition of SAMHD1 Using the Differential Properties of Rp- and Sp-dNTPαS Diastereomers. Biochemistry. 2021 Jun 1;60(21):1682-1698. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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