Steroid sulfatase-IN-11
Steroid sulfatase-IN-11 is a steroid sulfatase inhibitor, which functionally inhibits steroid sulfatase activity, reducing the enzyme's ability to hydrolyze steroid sulfates. Steroid sulfatase-IN-11 can be used for the research of hormone-dependent cancers.
For research use only. We do not sell to patients.
- CAS No.: 3075596-38-9
- Formula: C14H9F2N3O4S
- Molecular Weight:353.30
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
Steroid sulfatase-IN-11 (compound 9j) (0.1-10 μM) potently inhibits isolated human placental STS, reducing residual activity to 31.2%, 7.9% and 4.6% at concentrations of 0.1 μM, 1 μM and 10 μM, respectively[1].
Steroid sulfatase-IN-11 (0.1-10 μM) potently inhibits STS activity in JEG-3 cells, with an IC50 value of 6.64 nM; it reduces the residual activity to 10.8% at a concentration of 0.1 μM, to 0.9% at 1 μM, and achieves complete inhibition at 10 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 3075596-38-9
-
Molecular Weight 353.30
-
Formula C14H9F2N3O4S
-
SMILES
O=S(OC1=CC=C(C2=NOC(C3=CC(F)=CC(F)=C3)=N2)C=C1)(N)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Steroid sulfatase-IN-11 Related Classifications
HY-181408 Related Classifications
Powered by Bioz