Steroid sulfatase-IN-12
Steroid sulfatase-IN-12 is a steroid sulfatase inhibitor. Steroid sulfatase-IN-12 inhibits the activity of steroid sulfatase. Steroid sulfatase-IN-12 can be used in research related to hormone receptor-positive/HER2-negative breast cancer.
For research use only. We do not sell to patients.
- Formula: C22H30FN5O5S
- Molecular Weight:495.57
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Steroid sulfatase-IN-12 (compound 1f) (0.010-1 μM; 1 h) potently inhibits steroid sulfatase activity in JEG-3 placental cell lysates, with an IC50 of 21.44 nM[1].
Steroid sulfatase-IN-12 (0.010-1 μM; 20 h) potently inhibits steroid sulfatase activity in intact JEG-3 cell monolayers, with an IC50 of 20.39 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 495.57
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Formula C22H30FN5O5S
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SMILES
NS(=O)(OC1=CC=C(C=C1F)NC(N2CCN(CC2)C(NC34CC5CC(C4)CC(C3)C5)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)