Stigmasterol glucoside
Based on 1 publication(s) in Google Scholar
Stigmasterol glucoside is a sterol compound and a 5α-reductase inhibitor with an IC50 value of 27.2 µM. Stigmasterol glucoside has certain anti-inflammatory, antioxidant, and anti-tumor activities.
For research use only. We do not sell to patients.
- Purity : 99.54%
- CAS No.: 19716-26-8
- Formula: C35H58O6
- Molecular Weight:574.83
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Storage:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
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HY-N0410
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HY-N7510
12-O-Methylcarnosic acid5 alpha Reductase Inhibitor -
HY-N3557
Cauloside A -
HY-107385R
Epristeride (Standard)Human Steroid 5α-reductase Isoform 2 Inhibitor -
HY-106951
MK 3865 alpha Reductase Inhibitor -
HY-13613
Dutasteride5α-Reductase Isozyme Inhibitor -
HY-13635R
Finasteride (Standard) -
HY-N7510R
12-O-Methylcarnosic acid (Standard)5 alpha Reductase Inhibitor -
HY-13635A
Finasteride acetateType II 5α-Reductase Inhibitor
Publications Citing Use of MedChemExpress (MCE) Stigmasterol glucoside
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Biological Activity
Description
IC50 & Target
IC50：27.2 µM (5α-reductase)[2]
Cellular Effect
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Cell Line
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Type | Value | Description | References |
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| KB | IC50 |
>100 μM
Compound: sitosterol 3-O-beta-D-glucoside
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Cytotoxicity against human KB cells
Cytotoxicity against human KB cells
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[PMID: 12398543] |
In Vitro
Stigmasterol glucoside (1-200 µg/mL) combined with Daucosterol (HY-N0410) exhibits cytotoxicity against HeLa and MCF-7, with IC50 values of 37.0 µg/mL and 137.07 µg/mL, respectively[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 19716-26-8
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Appearance Solid
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Molecular Weight 574.83
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Formula C35H58O6
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Color White to off-white
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SMILES
OC[C@H]([C@@H](O)[C@H](O)[C@H]1O)O[C@@]1([H])O[C@H](C2)CC[C@@]3(C)C2=CC[C@]4([H])[C@]3([H])CC[C@@]5(C)[C@]4(CC[C@]5([H])[C@H](C)/C=C/[C@@H](CC)C(C)C)[H]
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Publications (1)
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Journal Impact Factor
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Most Recent
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
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Research Protocol for Inflammation-related Diseases
The NLRP3 inflammasome is a cytosolic innate immune signaling platform that integrates priming signals and danger-signal activation to promote caspase-1 activation, maturation of IL-1β and IL-18, and gasdermin D-mediated pyroptotic cell death. The core experimental logic is to determine whether inflammatory disease phenotypes are driven by increased NLRP3 expression, ASC-containing inflammasome assembly, caspase-1 cleavage, GSDMD cleavage, and extracellular release of IL-1β/IL-18 rather than by nonspecific cell injury alone. The pathway is strongly linked to inflammation-related disease phenotypes because monosodium urate crystals activate NALP3/NLRP3 inflammasome signaling in gout-like crystal inflammation, cholesterol crystals activate NLRP3 inflammasomes in atherogenesis models, and DSS-induced intestinal inflammation has been reported to involve NLRP3 inflammasome activity. However, experimental colitis studies also show context-dependent protective effects of NLRP3 inflammasome co
Purity & Documentation
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Data Sheet (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Stigmasterol glucoside Related Classifications
HY-N1200 Related Classifications
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