Substance P (3-11) acetate
Based on 1 Customer Validation
Substance P (3-11) acetate is a substance P (SP) fragment peptide that can cross the BBB. Substance P (3-11) acetate has contracting activities on guinea pig ileum. Substance P (3-11) acetate also promotes human monocyte chemotaxis.
For research use only. We do not sell to patients.
- Formula: C52H79N13O11S.xC2H4O2
- Molecular Weight:1094.33 (free base)
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
Chemical Information
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Appearance Solid
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Molecular Weight 1094.33 (free base)
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Formula C52H79N13O11S.xC2H4O2
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Sequence
Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2
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Sequence Shortening
KPQQFFGLM-NH2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 50 mg/mL (Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Yanaihara N, et al. Immunological aspects of secretin, substance P, and VIP. Gastroenterology. 1977 Apr;72(4 Pt.2):803-10. [Content Brief]
[2]. Chappa AK, et al. Characteristics of substance P transport across the blood-brain barrier. Pharm Res. 2006 Jun;23(6):1201-8. [Content Brief]
[3]. Ruff MR, et al. Substance P receptor-mediated chemotaxis of human monocytes. Peptides. 1985;6 Suppl 2:107-11. [Content Brief]
[4]. Sertl K, et al. Substance P: the relationship between receptor distribution in rat lung and the capacity of substance P to stimulate vascular permeability. Am Rev Respir Dis. 1988 Jul;138(1):151-9. [Content Brief]
[5]. Freed AL, et al. Investigation of substance P transport across the blood-brain barrier. Peptides. 2002 Jan;23(1):157-65. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)