1. PROTAC
  2. Ligands for E3 Ligase
  3. Thalidomide-5-O-C4-NH2 hydrochloride

Thalidomide-5-O-C4-NH2 hydrochloride 

Cat. No.: HY-149561 Purity: 99.98%
COA Handling Instructions

Thalidomide-5-O-C4-NH2 hydrochloride is the Thalidomide (HY-10984)-based cereblon ligand used in the recruitment of CRBN protein.Thalidomide-5-O-C4-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTACs.

For research use only. We do not sell to patients.

Thalidomide-5-O-C4-NH2 hydrochloride Chemical Structure

Thalidomide-5-O-C4-NH2 hydrochloride Chemical Structure

CAS No. : 2694727-93-8

Size Price Stock Quantity
5 mg USD 312 In-stock
10 mg USD 500 In-stock
50 mg   Get quote  
100 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Top Publications Citing Use of Products

View All Ligands for E3 Ligase Isoform Specific Products:

  • Biological Activity

  • Purity & Documentation

  • Customer Review

Description

Thalidomide-5-O-C4-NH2 hydrochloride is the Thalidomide (HY-10984)-based cereblon ligand used in the recruitment of CRBN protein.Thalidomide-5-O-C4-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTACs[1].

Molecular Weight

381.81

Formula

C17H20ClN3O5

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C1C(C=CC(OCCCCN)=C2)=C2C(N1C(CC3)C(NC3=O)=O)=O.Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Purity & Documentation
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Thalidomide-5-O-C4-NH2 hydrochloride Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Thalidomide-5-O-C4-NH2 hydrochloride
Cat. No.:
HY-149561
Quantity:
MCE Japan Authorized Agent: