2. Apoptosis Cytoskeleton Cell Cycle/DNA Damage
  3. Apoptosis Microtubule/Tubulin
  4. Tubulin inhibitor 42

Tubulin inhibitor 42 dose-dependently inhibited the activity of β-microtubulin (IC50 = 3.5 µM).Tubulin inhibitor 42 interferes with microtubule dynamic homeostasis, resulting in the arrest of the cancer cell cycle in the G2/M phase and inducing apoptosis. Tubulin inhibitor 42 significantly inhibits the angiogenic process in vitro and in vivo, preventing vascularization and tumor growth.

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Tubulin inhibitor 42 Chemical Structure

Tubulin inhibitor 42 Chemical Structure

CAS No. : 2135713-96-9

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Tubulin inhibitor 42 Related Antibodies

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Description

Tubulin inhibitor 42 dose-dependently inhibited the activity of β-microtubulin (IC50 = 3.5 µM).Tubulin inhibitor 42 interferes with microtubule dynamic homeostasis, resulting in the arrest of the cancer cell cycle in the G2/M phase and inducing apoptosis. Tubulin inhibitor 42 significantly inhibits the angiogenic process in vitro and in vivo, preventing vascularization and tumor growth[1].

Molecular Weight

389.40

Formula

C20H23NO7
CAS No.
Unlabeled Cas

SMILES

OC[C@H]1[C@H](C2=CC(O)=C(C=C2)OC)N(C3=CC(OC)=C(C(OC)=C3)OC)C1=O
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Room temperature in continental US; may vary elsewhere.
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Purity & Documentation
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Tubulin inhibitor 42 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tubulin inhibitor 422135713-96-9Tubulin inhibitor42Tubulin inhibitor-42ApoptosisMicrotubule/TubulinA2780HelaSKOV-3MDA-MB-231Anti-proliferativeAngiogenesis inhibitionCell cycle arrestInhibitorinhibitorinhibit

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