2. Cell Cycle/DNA Damage Cytoskeleton
  3. Microtubule/Tubulin
  4. Tubulin polymerization-IN-50

Tubulin polymerization-IN-50 (compound 7n) is a inhibitor of tubulin polymerization, with the IC50 of 5.05 μM in SK-Mel-28 cells. Tubulin polymerization-IN-50 induces the cell cycle arrest in the G2/M phase.

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Tubulin polymerization-IN-50 Chemical Structure

Tubulin polymerization-IN-50 Chemical Structure

CAS No. : 2998928-21-3

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Tubulin polymerization-IN-50 Related Antibodies

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Description

Tubulin polymerization-IN-50 (compound 7n) is a inhibitor of tubulin polymerization, with the IC50 of 5.05 μM in SK-Mel-28 cells. Tubulin polymerization-IN-50 induces the cell cycle arrest in the G2/M phase[1].

IC50 & Target

5.05 μM(SK-Mel-28 cells)[1]
Molecular Weight

417.43

Formula

C24H20FN3O3
CAS No.
SMILES

COC1=CC(C2=NC3=C(N2)C=CC(F)=C3)=CC=C1OCC(N4CCC5=C4C=CC=C5)=O
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Purity & Documentation
References
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Tubulin polymerization-IN-50 Related Classifications

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tubulin polymerization-IN-502998928-21-3Microtubule/Tubulintubulin polymerizationcell cycleSK-Mel-28Benzimidazole derivativesInhibitorinhibitorinhibit

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