Tyrosinase-IN-51
Tyrosinase-IN-51 is a tyrosinase inhibitor with an IC50 value of 340 nM. Tyrosinase-IN-51 can be used in studies related to pigmented skin diseases such as melasma, melanosis, freckles, and senile plaques.
For research use only. We do not sell to patients.
- CAS No.: 2302-93-4
- Formula: C9H11N3S
- Molecular Weight:193.27
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
Tyrosinase 340 nM (IC50) |
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| B16 | IC50 |
2.3 μM
Compound: 2a
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Inhibition of alpha-MSH-induced melanin production in mouse B16 cells after 3 days
Inhibition of alpha-MSH-induced melanin production in mouse B16 cells after 3 days
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[PMID: 21601449] |
In Vitro
Tyrosinase-IN-51 (compound 9) is an active tyrosinase inhibitor with an experimental IC50 of 340 nmol/L, and the Hypo1 pharmacophore model accurately predicts its active classification[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2302-93-4
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Molecular Weight 193.27
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Formula C9H11N3S
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SMILES
S=C(N)NN=C(C=1C=CC=CC1)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Tyrosinase-IN-51 Related Classifications
HY-W1060179 Related Classifications
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