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Cat. No.: HY-W1060179

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Tyrosinase-IN-51

Tyrosinase-IN-51 is a tyrosinase inhibitor with an IC₅₀ value of 340 nM. Tyrosinase-IN-51 can be used in studies related to pigmented skin diseases such as melasma, melanosis, freckles, and senile plaques.

For research use only. We do not sell to patients.

CAS No.: 2302-93-4
Formula: C₉H₁₁N₃S
Molecular Weight:193.27

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Tyrosinase-IN-51 Chemical Structure

CAS No.: 2302-93-4

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

IC₅₀ & Target^[1]

Tyrosinase

340 nM (IC₅₀)

In Vitro

Tyrosinase-IN-51 (compound 9) is an active tyrosinase inhibitor with an experimental IC₅₀ of 340 nmol/L, and the Hypo1 pharmacophore model accurately predicts its active classification^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2302-93-4
Molecular Weight 193.27
Formula C₉H₁₁N₃S
SMILES

S=C(N)NN=C(C=1C=CC=CC1)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Ghayas S, et al. 3D QSAR pharmacophore-based virtual screening for the identification of potential inhibitors of tyrosinase. Journal of biomolecular structure & dynamics. 2020 Jul;38(10):2916-2927. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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