Xanthine oxidoreductase-IN-4
Xanthine oxidoreductase-IN-4 is an orally active xanthine oxidoreductase (XOR) inhibitor. Xanthine oxidoreductase-IN-4 has inhibitory activity against XOR with an IC50 value of 29.3 nM. Xanthine oxidoreductase-IN-4 can be used for the research of hyperuricemia.
For research use only. We do not sell to patients.
- CAS No.: 1026587-58-5
- Formula: C16H15N5O2
- Molecular Weight:309.32
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
IC50: 29.3 nM (XOR)[1]
In Vitro
Xanthine oxidoreductase-IN-4 (Compound IIIc) has inhibitory activity against XOR with an IC50 value of 29.3 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Mice acute hyperuricemia model[1]
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Dosage:5 mg/kg
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Administration:Oral
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Result:Reduced serum levels of uric acid significantly from 4 h after administration.
Chemical Information
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CAS No. 1026587-58-5
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Molecular Weight 309.32
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Formula C16H15N5O2
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SMILES
CCOC1=CC=C(C=C1)NC(C2=CC=C(C=C2)C3=NN=NN3)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)