12-Bromododecan-1-ol
Based on 1 Customer Validation
12-Bromododecan-1-ol (12-Bromododecanol) is a PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity : 99.19%
- CAS No.: 3344-77-2
- Formula: C12H25BrO
- Molecular Weight:265.24
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Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
All PROTAC Linkers Isoforms
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Biological Activity
Description
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E110 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3344-77-2
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Appearance Solid
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Molecular Weight 265.24
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Formula C12H25BrO
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SMILES
BrCCCCCCCCCCCCO
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Synonyms
12-Bromododecanol
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (377.02 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (237 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.7702 mL | 18.8509 mL | 37.7017 mL | 94.2543 mL |
| 5 mM | 0.7540 mL | 3.7702 mL | 7.5403 mL | 18.8509 mL | |
| 10 mM | 0.3770 mL | 1.8851 mL | 3.7702 mL | 9.4254 mL | |
| 15 mM | 0.2513 mL | 1.2567 mL | 2.5134 mL | 6.2836 mL | |
| 20 mM | 0.1885 mL | 0.9425 mL | 1.8851 mL | 4.7127 mL | |
| 25 mM | 0.1508 mL | 0.7540 mL | 1.5081 mL | 3.7702 mL | |
| 30 mM | 0.1257 mL | 0.6284 mL | 1.2567 mL | 3.1418 mL | |
| 40 mM | 0.0943 mL | 0.4713 mL | 0.9425 mL | 2.3564 mL | |
| 50 mM | 0.0754 mL | 0.3770 mL | 0.7540 mL | 1.8851 mL | |
| 60 mM | 0.0628 mL | 0.3142 mL | 0.6284 mL | 1.5709 mL | |
| 80 mM | 0.0471 mL | 0.2356 mL | 0.4713 mL | 1.1782 mL | |
| 100 mM | 0.0377 mL | 0.1885 mL | 0.3770 mL | 0.9425 mL |
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