2-(2,6-Dioxopiperidin-3-yl)phthalimidine-azetidine
2-(2,6-Dioxopiperidin-3-yl)phthalimidine-azetidine is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.
For research use only. We do not sell to patients.
- CAS No.: 2698398-70-6
- Formula: C16H17N3O3
- Molecular Weight:299.33
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
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Help & FAQs
All E3 Ligase Ligand-Linker Conjugates Isoforms
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Biological Activity
Description
IC50 & Target
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Cereblon |
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2698398-70-6
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Molecular Weight 299.33
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Formula C16H17N3O3
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SMILES
O=C1NC(=O)C(N2C(=O)C3=CC=C(C=C3C2)C4CNC4)CC1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
2-(2,6-Dioxopiperidin-3-yl)phthalimidine-azetidine Related Classifications
HY-W1115220 Related Classifications
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