2. PROTAC
  3. E3 Ligase Ligand-Linker Conjugates
  4. 2-(2,6-Dioxopiperidin-3-yl)phthalimidine-O-piperidine

2-(2,6-Dioxopiperidin-3-yl)phthalimidine-O-piperidine 

Cat. No.: HY-W1112836
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2-(2,6-Dioxopiperidin-3-yl)phthalimidine-O-piperidine is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.

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2-(2,6-Dioxopiperidin-3-yl)phthalimidine-O-piperidine

2-(2,6-Dioxopiperidin-3-yl)phthalimidine-O-piperidine Estructura química

No. CAS : 2222115-81-1

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2-(2,6-Dioxopiperidin-3-yl)phthalimidine-O-piperidine Related Antibodies

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von Hippel-Lindau (VHL) MDM2 Cereblon cIAP1 Aryl Hydrocarbon Receptor TRIM21

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Descripciòn

2-(2,6-Dioxopiperidin-3-yl)phthalimidine-O-piperidine is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.

IC50 & Target

Cereblon

 

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

2-(2,6-Dioxopiperidin-3-yl)phthalimidine-O-piperidine Related Antibodies
Peso molecular

343.38

Fòrmula

C18H21N3O4
No. CAS
SMILES

O=C1NC(=O)C(N2C(=O)C3=CC=C(OC4CCNCC4)C=C3C2)CC1
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
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2-(2,6-Dioxopiperidin-3-yl)phthalimidine-O-piperidine Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

2-(2,6-Dioxopiperidin-3-yl)phthalimidine-O-piperidine2222115-81-1E3 Ligase Ligand-Linker ConjugatesInhibitorinhibitorinhibit

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Nombre del producto:
2-(2,6-Dioxopiperidin-3-yl)phthalimidine-O-piperidine
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HY-W1112836
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