2',3',5'-Tri-O-acetyl-2-thiouridine
Based on 1 Customer Validation
2',3',5'-Tri-O-acetyl-2-thiouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
For research use only. We do not sell to patients.
- Purity: 99.27%
- CAS No.: 28542-31-6
- Formula: C15H18N2O8S
- Molecular Weight:386.38
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Chemical Information
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CAS No. 28542-31-6
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Appearance Solid
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Molecular Weight 386.38
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Formula C15H18N2O8S
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Color White to off-white
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SMILES
O=C(C=C1)NC(N1[C@@H]2O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H]2OC(C)=O)=S
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 250 mg/mL (647.03 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.5881 mL | 12.9406 mL | 25.8813 mL | 64.7031 mL |
| 5 mM | 0.5176 mL | 2.5881 mL | 5.1763 mL | 12.9406 mL | |
| 10 mM | 0.2588 mL | 1.2941 mL | 2.5881 mL | 6.4703 mL | |
| 15 mM | 0.1725 mL | 0.8627 mL | 1.7254 mL | 4.3135 mL | |
| 20 mM | 0.1294 mL | 0.6470 mL | 1.2941 mL | 3.2352 mL | |
| 25 mM | 0.1035 mL | 0.5176 mL | 1.0353 mL | 2.5881 mL | |
| 30 mM | 0.0863 mL | 0.4314 mL | 0.8627 mL | 2.1568 mL | |
| 40 mM | 0.0647 mL | 0.3235 mL | 0.6470 mL | 1.6176 mL | |
| 50 mM | 0.0518 mL | 0.2588 mL | 0.5176 mL | 1.2941 mL | |
| 60 mM | 0.0431 mL | 0.2157 mL | 0.4314 mL | 1.0784 mL | |
| 80 mM | 0.0324 mL | 0.1618 mL | 0.3235 mL | 0.8088 mL | |
| 100 mM | 0.0259 mL | 0.1294 mL | 0.2588 mL | 0.6470 mL |