1. Neuronal Signaling
  2. Cholinesterase (ChE)
  3. 2,3,9,10-Tetrahydroxyberberine bromide

2,3,9,10-Tetrahydroxyberberine bromide is an acetylcholinesterase AChE inhibitor (IC50=7.8 μM). 2,3,9,10-Tetrahydroxyberberine bromide exhibits DPPH free radical scavenging activity (IC50=43 μM) and is applicable to research related to Alzheimer's disease.

For research use only. We do not sell to patients.

2,3,9,10-Tetrahydroxyberberine bromide

2,3,9,10-Tetrahydroxyberberine bromide Chemical Structure

CAS No. : 2847856-62-4

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Description

2,3,9,10-Tetrahydroxyberberine bromide is an acetylcholinesterase AChE inhibitor (IC50=7.8 μM). 2,3,9,10-Tetrahydroxyberberine bromide exhibits DPPH free radical scavenging activity (IC50=43 μM) and is applicable to research related to Alzheimer's disease[1].

IC50 & Target

AChE

7.8 μM (IC50)

Molecular Weight

376.20

Formula

C17H14BrNO4

CAS No.
SMILES

OC1=C(O)C2=C[N+]3=C(C4=CC(O)=C(C=C4CC3)O)C=C2C=C1.[Br-]

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
2,3,9,10-Tetrahydroxyberberine bromide
Cat. No.:
HY-N11962A
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