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Cat. No.: HY-100564AR

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2',3'-cGAMP sodium (Standard)

Name: 2',3'-cGAMP sodium (Standard)
Brand: MedChemExpress
SKU: HY-100564AR
Availability: PreOrder

(Synonyms: 2'-3'-cyclic GMP-AMP sodium (Standard))

2',3'-cGAMP sodium (Standard) is the analytical standard of 2',3'-cGAMP sodium (HY-100564A). This product is intended for research and analytical applications. 2',3'-cGAMP sodium (2'-3'-cyclic GMP-AMP sodium) is a endogenous cGAMP in mammalian cells. 2',3'-cGAMP sodium binds to STING with a high affinity and is a potent inducer of interferon-β (IFNβ). 2',3'-cGAMP sodium is produced in mammalian cells in response to DNA in the cytoplasm.

For research use only. We do not sell to patients.

CAS No.: 2734858-36-5
Formula: C₂₀H₂₂N₁₀Na₂O₁₃P₂
Molecular Weight:718.37

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

2',3'-cGAMP sodium (Standard) Chemical Structure

CAS No.: 2734858-36-5

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Product Information

Information

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 2734858-36-5
Molecular Weight 718.37
Formula C₂₀H₂₂N₁₀Na₂O₁₃P₂
SMILES

OC1([H])[C@](OP(OC[C@](O[C@@H](N2C3=NC=NC(N)=C3N=C2)[C@@H]4O)([H])[C@@]4([H])O5)(O[Na])=O)([H])[C@H](N6C(NC(N)=NC7=O)=C7N=C6)O[C@]1([H])COP5(O[Na])=O
Synonyms

2'-3'-cyclic GMP-AMP sodium (Standard)
Structure Classification
- Others
Initial Source
- Endogenous metabolite
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Zhang X, et al. Cyclic GMP-AMP containing mixed phosphodiester linkages is an endogenous high-affinity ligand for STING. Mol Cell. 2013 Jul 25;51(2):226-35. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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