2-Chloro-3-nitro-5-(trifluoromethyl)benzoic acid (Synonyms: 2-Chloro-3-nitro-5-(trifluoromethyl))

Cat. No.: HY-W005717 Purity: 99.83%: Data Sheet
COA

SDS
Handling Instructions
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2-Chloro-3-nitro-5-(trifluoromethyl)benzoic acid (2-Chloro-3-nitro-5-(trifluoromethyl)) is a drug intermediate for synthesis of various active compounds.

For research use only. We do not sell to patients.

2-Chloro-3-nitro-5-(trifluoromethyl)benzoic acid Chemical Structure

CAS No. : 22227-59-4

Size	Stock	Quantity

Free Sample (0.1 - 0.2 mg)	Apply Now
Free Sample (0.1 - 0.2 mg)	Apply Now
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	In-stock	Estimated Time of Arrival: December 31
Solid
250 mg	In-stock	Estimated Time of Arrival: December 31
500 mg	In-stock	Estimated Time of Arrival: December 31
1 g	In-stock	Estimated Time of Arrival: December 31
5 g	In-stock	Estimated Time of Arrival: December 31
10 g	In-stock	Estimated Time of Arrival: December 31
25 g	In-stock	Estimated Time of Arrival: December 31
50 g	Get quote

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Description

2-Chloro-3-nitro-5-(trifluoromethyl)benzoic acid (2-Chloro-3-nitro-5-(trifluoromethyl)) is a drug intermediate for synthesis of various active compounds.

Molecular Weight

269.56

Formula

C₈H₃ClF₃NO₄

CAS No.

22227-59-4

Appearance

Solid

Color

White to light yellow

SMILES

O=C(O)C1=CC(C(F)(F)F)=CC([N+]([O-])=O)=C1Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Store at room temperature 3 years

In solvent	-80°C	2 years
	-20°C	1 year

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (370.97 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.7097 mL	18.5487 mL	37.0975 mL
5 mM	0.7419 mL	3.7097 mL	7.4195 mL
10 mM	0.3710 mL	1.8549 mL	3.7097 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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mg/kg

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(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.83%

Select Batch:

Data Sheet (246 KB) SDS (393 KB)

COA (252 KB) HNMR (256 KB) RP-HPLC (87 KB) MS (70 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.7097 mL	18.5487 mL	37.0975 mL	92.7437 mL
	5 mM	0.7419 mL	3.7097 mL	7.4195 mL	18.5487 mL
	10 mM	0.3710 mL	1.8549 mL	3.7097 mL	9.2744 mL
	15 mM	0.2473 mL	1.2366 mL	2.4732 mL	6.1829 mL
	20 mM	0.1855 mL	0.9274 mL	1.8549 mL	4.6372 mL
	25 mM	0.1484 mL	0.7419 mL	1.4839 mL	3.7097 mL
	30 mM	0.1237 mL	0.6183 mL	1.2366 mL	3.0915 mL
	40 mM	0.0927 mL	0.4637 mL	0.9274 mL	2.3186 mL
	50 mM	0.0742 mL	0.3710 mL	0.7419 mL	1.8549 mL
	60 mM	0.0618 mL	0.3091 mL	0.6183 mL	1.5457 mL
	80 mM	0.0464 mL	0.2319 mL	0.4637 mL	1.1593 mL
	100 mM	0.0371 mL	0.1855 mL	0.3710 mL	0.9274 mL

2-Chloro-3-nitro-5-(trifluoromethyl)benzoic acid Related Classifications

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Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

2-Chloro-3-nitro-5-(trifluoromethyl)benzoic acid22227-59-42-Chloro-3-nitro-5-(trifluoromethyl)Drug IntermediateDrug IintermediateInhibitorinhibitorinhibit

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2-Chloro-3-nitro-5-(trifluoromethyl)benzoic acid (Synonyms: 2-Chloro-3-nitro-5-(trifluoromethyl))

2-Chloro-3-nitro-5-(trifluoromethyl)benzoic acid Related Antibodies

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