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  2. Isotope-Labeled Compounds Biochemical Assay Reagents
  3. 2-Deoxy-2-fluoro-D-glucose-13C

2-Deoxy-2-fluoro-D-glucose-13C is the 13C labeled 2-Deoxy-2-fluoro-D-glucose (HY-141637). 2-Deoxy-2-fluoro-D-glucose (2-Fluoro-2-deoxy-D-glucose) is a glucose analog that can be absorbed by cells. 2-Deoxy-2-fluoro-D-glucose is capable of being labelled with 18F for positron emission tomography (PET) imaging. 18F-2-Deoxy-2-fluoro-D-glucose can be used to detect breast cancer and gastric cancer.

For research use only. We do not sell to patients.

2-Deoxy-2-fluoro-D-glucose-<sup>13</sup>C

2-Deoxy-2-fluoro-D-glucose-13C Chemical Structure

CAS No. : 478518-95-5

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Description

2-Deoxy-2-fluoro-D-glucose-13C is the 13C labeled 2-Deoxy-2-fluoro-D-glucose (HY-141637). 2-Deoxy-2-fluoro-D-glucose (2-Fluoro-2-deoxy-D-glucose) is a glucose analog that can be absorbed by cells. 2-Deoxy-2-fluoro-D-glucose is capable of being labelled with 18F for positron emission tomography (PET) imaging. 18F-2-Deoxy-2-fluoro-D-glucose can be used to detect breast cancer and gastric cancer[1][2].

Application

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

183.14

Formula

C513CH11FO5

CAS No.
Unlabeled CAS
Appearance

Solid

SMILES

OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](F)[13CH]=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 25 mg/mL (136.51 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.4603 mL 27.3015 mL 54.6030 mL
5 mM 1.0921 mL 5.4603 mL 10.9206 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 5.4603 mL 27.3015 mL 54.6030 mL 136.5076 mL
5 mM 1.0921 mL 5.4603 mL 10.9206 mL 27.3015 mL
10 mM 0.5460 mL 2.7302 mL 5.4603 mL 13.6508 mL
15 mM 0.3640 mL 1.8201 mL 3.6402 mL 9.1005 mL
20 mM 0.2730 mL 1.3651 mL 2.7302 mL 6.8254 mL
25 mM 0.2184 mL 1.0921 mL 2.1841 mL 5.4603 mL
30 mM 0.1820 mL 0.9101 mL 1.8201 mL 4.5503 mL
40 mM 0.1365 mL 0.6825 mL 1.3651 mL 3.4127 mL
50 mM 0.1092 mL 0.5460 mL 1.0921 mL 2.7302 mL
60 mM 0.0910 mL 0.4550 mL 0.9101 mL 2.2751 mL
80 mM 0.0683 mL 0.3413 mL 0.6825 mL 1.7063 mL
100 mM 0.0546 mL 0.2730 mL 0.5460 mL 1.3651 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
2-Deoxy-2-fluoro-D-glucose-13C
Cat. No.:
HY-141637S
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