(2S,3S,11bR)-Dihydrotetrabenazine
(2S,3S,11bR)-Dihydrotetrabenazine ((2S,3S,11bR)-DHTBZ) is a highly selective inhibitor of vesicular monoamine transporter 2 (VMAT2) with a Ki value of 593 nM. (2S,3S,11bR)-Dihydrotetrabenazine inhibits vesicular transport of monoamine neurotransmitters like dopamine and serotonin, reducing their synaptic release. (2S,3S,11bR)-Dihydrotetrabenazine is promising for research of Huntington's chorea and other hyperkinetic disorders.
For research use only. We do not sell to patients.
- CAS No.: 862377-27-3
- Formula: C19H29NO3
- Molecular Weight:319.44
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 862377-27-3
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Molecular Weight 319.44
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Formula C19H29NO3
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SMILES
COC1=C(OC)C=C2CCN(C[C@@H]([C@H](C3)O)CC(C)C)[C@@]3([H])C2=C1
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Synonyms
(2S,3S,11bR)-DHTBZ
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)