30-Hydroxylup-20(29)-en-3-one
30-Hydroxylup-20(29)-en-3-one is a Triterpenoids product that can be isolated from the herbs of Maytenus austroyunnanensis.
For research use only. We do not sell to patients.
- CAS No.: 72944-06-0
- Formula: C30H48O2
- Molecular Weight:440.70
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A2780 | IC50 |
>10 μM
Compound: 16
|
Cytotoxicity against human A2780 cells after 96 hrs by MTT assay
Cytotoxicity against human A2780 cells after 96 hrs by MTT assay
|
[PMID: 24467317] |
| A2780 | IC50 |
16.4 μg/mL
Compound: 4
|
Cytotoxicity against human A2780 cells by clonogenic assay
Cytotoxicity against human A2780 cells by clonogenic assay
|
[PMID: 16499334] |
| A549 | IC50 |
>10 μM
Compound: 16
|
Cytotoxicity against human A549 cells after 96 hrs by MTT assay
Cytotoxicity against human A549 cells after 96 hrs by MTT assay
|
[PMID: 24467317] |
| B16 | IC50 |
9.2 μg/mL
Compound: 30-hydroxylup-20(29)-en-3-one
|
Cytotoxicity against mouse B16 cells
Cytotoxicity against mouse B16 cells
|
[PMID: 18590313] |
| Bel-7402 | IC50 |
>10 μM
Compound: 16
|
Cytotoxicity against human Bel7402 cells after 96 hrs by MTT assay
Cytotoxicity against human Bel7402 cells after 96 hrs by MTT assay
|
[PMID: 24467317] |
| BGC-823 | IC50 |
>10 μM
Compound: 16
|
Cytotoxicity against human BGC823 cells after 96 hrs by MTT assay
Cytotoxicity against human BGC823 cells after 96 hrs by MTT assay
|
[PMID: 24467317] |
| BV-2 | IC50 |
>10 μM
Compound: 16
|
Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess method
Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess method
|
[PMID: 24467317] |
| HCT-8 | IC50 |
>10 μM
Compound: 16
|
Cytotoxicity against human HCT8 cells after 96 hrs by MTT assay
Cytotoxicity against human HCT8 cells after 96 hrs by MTT assay
|
[PMID: 24467317] |
Chemical Information
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CAS No. 72944-06-0
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Molecular Weight 440.70
-
Formula C30H48O2
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SMILES
C[C@]12[C@@](CC[C@@]3([H])[C@]2(CC[C@]4([H])[C@@]3(CCC(C4(C)C)=O)C)C)([H])[C@]5([H])[C@@](CC1)(CC[C@H]5C(CO)=C)C
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Structure Classification
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)