4,5-Dibromo-2-pyrrolic acid
Based on 1 Customer Validation
4,5-Dibromo-2-pyrrolic acid (compound 2) is an immunosuppressive compound. 4,5-Dibromo-2-pyrrolic acid suppresses the proliferative response of splenocytes to suboptimal concentrations of the mitogen, concanavalin A (Con A).
For research use only. We do not sell to patients.
- Purity: 99.34%
- CAS No.: 34649-21-3
- Formula: C5H3Br2NO2
- Molecular Weight:268.89
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Storage:
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
All Galectin Isoforms
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Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| L6 | IC50 |
>90 μg/mL
Compound: 3a
|
Cytotoxicity against rat L6 cells after 72 hrs
Cytotoxicity against rat L6 cells after 72 hrs
|
[PMID: 17765547] |
Chemical Information
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CAS No. 34649-21-3
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Appearance Solid
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Molecular Weight 268.89
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Formula C5H3Br2NO2
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Color Brown to reddish brown
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SMILES
C1=C(C(=O)O)NC(=C1Br)Br
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Structure Classification
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Initial Source
Agelas flabelliformis
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvent & Solubility
DMSO : 50 mg/mL (185.95 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.7190 mL | 18.5950 mL | 37.1899 mL | 92.9748 mL |
| 5 mM | 0.7438 mL | 3.7190 mL | 7.4380 mL | 18.5950 mL | |
| 10 mM | 0.3719 mL | 1.8595 mL | 3.7190 mL | 9.2975 mL | |
| 15 mM | 0.2479 mL | 1.2397 mL | 2.4793 mL | 6.1983 mL | |
| 20 mM | 0.1859 mL | 0.9297 mL | 1.8595 mL | 4.6487 mL | |
| 25 mM | 0.1488 mL | 0.7438 mL | 1.4876 mL | 3.7190 mL | |
| 30 mM | 0.1240 mL | 0.6198 mL | 1.2397 mL | 3.0992 mL | |
| 40 mM | 0.0930 mL | 0.4649 mL | 0.9297 mL | 2.3244 mL | |
| 50 mM | 0.0744 mL | 0.3719 mL | 0.7438 mL | 1.8595 mL | |
| 60 mM | 0.0620 mL | 0.3099 mL | 0.6198 mL | 1.5496 mL | |
| 80 mM | 0.0465 mL | 0.2324 mL | 0.4649 mL | 1.1622 mL | |
| 100 mM | 0.0372 mL | 0.1859 mL | 0.3719 mL | 0.9297 mL |