4,5-Dibromo-2-pyrrolic acid

Cat. No.: HY-W340234 Purity: 99.34%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

4,5-Dibromo-2-pyrrolic acid (compound 2) is an immunosuppressive compound. 4,5-Dibromo-2-pyrrolic acid suppresses the proliferative response of splenocytes to suboptimal concentrations of the mitogen, concanavalin A (Con A).

For research use only. We do not sell to patients.

4,5-Dibromo-2-pyrrolic acid Chemical Structure

CAS No. : 34649-21-3

Size	Stock	Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	In-stock	Estimated Time of Arrival: December 31
Solid
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	In-stock	Estimated Time of Arrival: December 31
100 mg	In-stock	Estimated Time of Arrival: December 31
200 mg	Get quote
500 mg	Get quote

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This product is a controlled substance and not for sale in your territory.

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Cellular Effect

Cell Line	Type	Value	Description	References
L6	IC₅₀	> 90 μg/mL Compound: 3a	Cytotoxicity against rat L6 cells after 72 hrs Cytotoxicity against rat L6 cells after 72 hrs	[PMID: 17765547]

Molecular Weight

268.89

Formula

C₅H₃Br₂NO₂

CAS No.

34649-21-3

Appearance

Solid

Color

Brown to reddish brown

SMILES

C1=C(C(=O)O)NC(=C1Br)Br

Structure Classification

Ketones, Aldehydes, Acids

Initial Source

Animals

Agelas flabelliformis

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility

In Vitro:

DMSO : 50 mg/mL (185.95 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.7190 mL	18.5950 mL	37.1899 mL
5 mM	0.7438 mL	3.7190 mL	7.4380 mL
10 mM	0.3719 mL	1.8595 mL	3.7190 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.34%

Select Batch:

Data Sheet (270 KB) SDS (393 KB)

COA (250 KB) HNMR (245 KB) LCMS (93 KB)

Handling Instructions (2659 KB)

References

[1]. S P Gunasekera, et al. Immunosuppressive compounds from a deep water marine sponge, Agelas flabelliformis. J Nat Prod. 1989 Jul-Aug;52(4):757-61 [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.7190 mL	18.5950 mL	37.1899 mL	92.9748 mL
	5 mM	0.7438 mL	3.7190 mL	7.4380 mL	18.5950 mL
	10 mM	0.3719 mL	1.8595 mL	3.7190 mL	9.2975 mL
	15 mM	0.2479 mL	1.2397 mL	2.4793 mL	6.1983 mL
	20 mM	0.1859 mL	0.9297 mL	1.8595 mL	4.6487 mL
	25 mM	0.1488 mL	0.7438 mL	1.4876 mL	3.7190 mL
	30 mM	0.1240 mL	0.6198 mL	1.2397 mL	3.0992 mL
	40 mM	0.0930 mL	0.4649 mL	0.9297 mL	2.3244 mL
	50 mM	0.0744 mL	0.3719 mL	0.7438 mL	1.8595 mL
	60 mM	0.0620 mL	0.3099 mL	0.6198 mL	1.5496 mL
	80 mM	0.0465 mL	0.2324 mL	0.4649 mL	1.1622 mL
	100 mM	0.0372 mL	0.1859 mL	0.3719 mL	0.9297 mL