4',5'-Didehydro-5'-deoxyuridine
Based on 1 Customer Validation
4',5'-Didehydro-5'-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
For research use only. We do not sell to patients.
- Purity: 99.25%
- CAS No.: 14365-63-0
- Formula: C9H10N2O5
- Molecular Weight:226.19
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Storage:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Biological Activity
Chemical Information
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CAS No. 14365-63-0
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Appearance Solid
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Molecular Weight 226.19
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Formula C9H10N2O5
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Color White to off-white
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SMILES
C=C1[C@@H](O)[C@@H](O)[C@H](N2C(NC(C=C2)=O)=O)O1
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Synonyms
1-(5-Deoxy-beta-D-erythro-pent-4-enofuranosyl)uracil
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvent & Solubility
DMSO : 100 mg/mL (442.11 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.4211 mL | 22.1053 mL | 44.2106 mL | 110.5265 mL |
| 5 mM | 0.8842 mL | 4.4211 mL | 8.8421 mL | 22.1053 mL | |
| 10 mM | 0.4421 mL | 2.2105 mL | 4.4211 mL | 11.0527 mL | |
| 15 mM | 0.2947 mL | 1.4737 mL | 2.9474 mL | 7.3684 mL | |
| 20 mM | 0.2211 mL | 1.1053 mL | 2.2105 mL | 5.5263 mL | |
| 25 mM | 0.1768 mL | 0.8842 mL | 1.7684 mL | 4.4211 mL | |
| 30 mM | 0.1474 mL | 0.7368 mL | 1.4737 mL | 3.6842 mL | |
| 40 mM | 0.1105 mL | 0.5526 mL | 1.1053 mL | 2.7632 mL | |
| 50 mM | 0.0884 mL | 0.4421 mL | 0.8842 mL | 2.2105 mL | |
| 60 mM | 0.0737 mL | 0.3684 mL | 0.7368 mL | 1.8421 mL | |
| 80 mM | 0.0553 mL | 0.2763 mL | 0.5526 mL | 1.3816 mL | |
| 100 mM | 0.0442 mL | 0.2211 mL | 0.4421 mL | 1.1053 mL |