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Referencia número: HY-W1060365

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4-((Aminooxy)methyl)phenol

4-((Aminooxy)methyl)phenol is an Indoleamine 2,3-dioxygenase-1 (IDO1) inhibitor with a human IC₅₀ of 61 μM. 4-((Aminooxy)methyl)phenol inhibits IDO1 catalytic activity and acts as a structural mimic of the enzyme's alkylperoxy transition or intermediate state. 4-((Aminooxy)methyl)phenol can be used for the research of cancer.

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No. CAS: 2089-12-5
Fòrmula: C₇H₉NO₂
Peso molecular:139.15

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Please store the product under the recommended conditions in the Certificate of Analysis.

4-((Aminooxy)methyl)phenol Chemical Structure

No. CAS: 2089-12-5

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Descripciòn

IC₅₀ & Target^[1]

IDO1

61 μM (IC₅₀)

Ver todos los productos específicos de isoformas Indoleamine 2,3-Dioxygenase (IDO) :

In Vitro

4-((Aminooxy)methyl)phenol (compound 31) inhibits recombinant human IDO1 with an IC₅₀ of 61 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

No. CAS 2089-12-5
Peso molecular 139.15
Fòrmula C₇H₉NO₂
SMILES

OC1=CC=C(C=C1)CON
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Instrucciones de manejo (2659 KB)

Referencias

[1]. Malachowski WP, et al. O-alkylhydroxylamines as rationally-designed mechanism-based inhibitors of indoleamine 2,3-dioxygenase-1. European journal of medicinal chemistry. 2016 Jan 27;108:564-576. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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4-((Aminooxy)methyl)phenol

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4-((Aminooxy)methyl)phenol

Ver todos los productos específicos de isoformas Indoleamine 2,3-Dioxygenase (IDO)

Actividad biológica

Chemical Information

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Referencias

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4-((Aminooxy)methyl)phenol Related Classifications

HY-W1060365 Related Classifications