4-Boc-aminomethyl-piperidine
Based on 1 Customer Validation
4-Boc-aminomethyl-piperidine is a PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 99.75%
- CAS No.: 135632-53-0
- Formula: C11H22N2O2
- Molecular Weight:214.31
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
All PROTAC Linkers Isoforms
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Biological Activity
PROTACs contain two different ligands connected by a linker; one is a ligand for an E371 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 135632-53-0
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Appearance Solid
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Molecular Weight 214.31
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Formula C11H22N2O2
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Color White to off-white
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SMILES
O=C(OC(C)(C)C)NCC1CCNCC1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 25 mg/mL (116.65 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (240 KB)
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SDS (477 KB)
- English - EN (477 KB)
- Français - FR (477 KB)
- Deutsch - DE (477 KB)
- Norwegian - NO (477 KB)
- Español - ES (477 KB)
- Swedish - SV (477 KB)
- Italian - IT (477 KB)
- Korean - KR (477 KB)
- Portuguese - PT (477 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.6661 mL | 23.3307 mL | 46.6614 mL | 116.6534 mL |
| 5 mM | 0.9332 mL | 4.6661 mL | 9.3323 mL | 23.3307 mL | |
| 10 mM | 0.4666 mL | 2.3331 mL | 4.6661 mL | 11.6653 mL | |
| 15 mM | 0.3111 mL | 1.5554 mL | 3.1108 mL | 7.7769 mL | |
| 20 mM | 0.2333 mL | 1.1665 mL | 2.3331 mL | 5.8327 mL | |
| 25 mM | 0.1866 mL | 0.9332 mL | 1.8665 mL | 4.6661 mL | |
| 30 mM | 0.1555 mL | 0.7777 mL | 1.5554 mL | 3.8884 mL | |
| 40 mM | 0.1167 mL | 0.5833 mL | 1.1665 mL | 2.9163 mL | |
| 50 mM | 0.0933 mL | 0.4666 mL | 0.9332 mL | 2.3331 mL | |
| 60 mM | 0.0778 mL | 0.3888 mL | 0.7777 mL | 1.9442 mL | |
| 80 mM | 0.0583 mL | 0.2916 mL | 0.5833 mL | 1.4582 mL | |
| 100 mM | 0.0467 mL | 0.2333 mL | 0.4666 mL | 1.1665 mL |
4-Boc-aminomethyl-piperidine Related Classifications
HY-40008 Related Classifications
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