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Cat. No.: HY-90002

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4-Phenylpiperidine

Name: 4-Phenylpiperidine
Brand: MedChemExpress
SKU: HY-90002
Price: 25.00 USD
Availability: InStock
Rating: 5 (1 reviews)

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4-Phenylpiperidine is a σ receptor ligand with a K_i value of 1980 nM for guinea pig σ receptors. 4-Phenylpiperidine binds to σ receptors. 4-Phenylpiperidine is used in psychiatric disease research.

For research use only. We do not sell to patients.

Purity : 99.86%
CAS No.: 771-99-3
Formula: C₁₁H₁₅N
Molecular Weight:161.24

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

4-Phenylpiperidine Chemical Structure

CAS No.: 771-99-3

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Solvent & Solubility
- In Vitro
Purity & Documentation
References
Help & FAQs
Classifications
Bioz

Biological Activity

Description

All Sigma Receptor Isoforms :

In Vitro

4-Phenylpiperidine binds to σ receptors in guinea pig brain cell membranes with a K_i value of 1980 nM, and its affinity is approximately 6-fold higher than that of 1-phenylpiperazine^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 771-99-3
Appearance Solid
Molecular Weight 161.24
Formula C₁₁H₁₅N
Color Off-white to yellow
SMILES

C1(C2=CC=CC=C2)CCNCC1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (620.19 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

View the Complete Stock Solution Preparation Table

Preparing Stock Solutions

View the Complete Stock Solution Preparation Table

Concentration Solvent Mass

1 mg

5 mg

10 mg

Concentration

Solvent

Mass

1 mM

6.2019 mL

31.0097 mL

62.0193 mL

5 mM

1.2404 mL

6.2019 mL

12.4039 mL

10 mM

0.6202 mL

3.1010 mL

6.2019 mL

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration Concentration

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Molecular Weight Molecular Weight

Dilution Calculator

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Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (278 KB)
SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Glennon RA, et al. Novel 1-phenylpiperazine and 4-phenylpiperidine derivatives as high-affinity sigma ligands. J Med Chem. 1991;34(12):3360-3365. [Content Brief]

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg
DMSO	1 mM	6.2019 mL	31.0097 mL	62.0193 mL	155.0484 mL
	5 mM	1.2404 mL	6.2019 mL	12.4039 mL	31.0097 mL
	10 mM	0.6202 mL	3.1010 mL	6.2019 mL	15.5048 mL
	15 mM	0.4135 mL	2.0673 mL	4.1346 mL	10.3366 mL
	20 mM	0.3101 mL	1.5505 mL	3.1010 mL	7.7524 mL
	25 mM	0.2481 mL	1.2404 mL	2.4808 mL	6.2019 mL
	30 mM	0.2067 mL	1.0337 mL	2.0673 mL	5.1683 mL
	40 mM	0.1550 mL	0.7752 mL	1.5505 mL	3.8762 mL
	50 mM	0.1240 mL	0.6202 mL	1.2404 mL	3.1010 mL
	60 mM	0.1034 mL	0.5168 mL	1.0337 mL	2.5841 mL
	80 mM	0.0775 mL	0.3876 mL	0.7752 mL	1.9381 mL
	100 mM	0.0620 mL	0.3101 mL	0.6202 mL	1.5505 mL

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Minimum order quantity

100 mg

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Biological Activity
- Description
- In Vitro
Chemical Information
Solvent & Solubility
- In Vitro
Purity & Documentation
References

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4-Phenylpiperidine

All Sigma Receptor Isoforms

Biological Activity

Description

In Vitro

Chemical Information

Solvent & Solubility

In Vitro:

Purity & Documentation

References

Help & FAQs

Complete Stock Solution Preparation Table

4-Phenylpiperidine Related Classifications

HY-90002 Related Classifications

Bioz

Keywords

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