4-Phenylpiperidine

Name: 4-Phenylpiperidine
Brand: MedChemExpress
SKU: HY-90002
Rating: 4.5 (1 reviews)

Cat. No.: HY-90002 Purity: 99.86%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

4-Phenylpiperidine is a σ receptor ligand with a K_i value of 1980 nM for guinea pig σ receptors. 4-Phenylpiperidine binds to σ receptors. 4-Phenylpiperidine is used in psychiatric disease research.

For research use only. We do not sell to patients.

4-Phenylpiperidine Chemical Structure

CAS No. : 771-99-3

Size	Stock	Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	In-stock	Estimated Time of Arrival: December 31
Solid
250 mg	In-stock	Estimated Time of Arrival: December 31
500 mg	In-stock	Estimated Time of Arrival: December 31
1 g	In-stock	Estimated Time of Arrival: December 31
5 g	Get quote
10 g	Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
Customer Review

Description

In Vitro

4-Phenylpiperidine binds to σ receptors in guinea pig brain cell membranes with a K_i value of 1980 nM, and its affinity is approximately 6-fold higher than that of 1-phenylpiperazine^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

161.24

Formula

C₁₁H₁₅N

CAS No.

771-99-3

Appearance

Solid

Color

Off-white to yellow

SMILES

C1(C2=CC=CC=C2)CCNCC1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (620.19 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	6.2019 mL	31.0097 mL	62.0193 mL
5 mM	1.2404 mL	6.2019 mL	12.4039 mL
10 mM	0.6202 mL	3.1010 mL	6.2019 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.9%

Select Batch:

Data Sheet (270 KB) SDS (394 KB)

COA (246 KB)

Handling Instructions (2659 KB)

References

[1]. Glennon RA, et al. Novel 1-phenylpiperazine and 4-phenylpiperidine derivatives as high-affinity sigma ligands. J Med Chem. 1991;34(12):3360-3365. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	6.2019 mL	31.0097 mL	62.0193 mL	155.0484 mL
	5 mM	1.2404 mL	6.2019 mL	12.4039 mL	31.0097 mL
	10 mM	0.6202 mL	3.1010 mL	6.2019 mL	15.5048 mL
	15 mM	0.4135 mL	2.0673 mL	4.1346 mL	10.3366 mL
	20 mM	0.3101 mL	1.5505 mL	3.1010 mL	7.7524 mL
	25 mM	0.2481 mL	1.2404 mL	2.4808 mL	6.2019 mL
	30 mM	0.2067 mL	1.0337 mL	2.0673 mL	5.1683 mL
	40 mM	0.1550 mL	0.7752 mL	1.5505 mL	3.8762 mL
	50 mM	0.1240 mL	0.6202 mL	1.2404 mL	3.1010 mL
	60 mM	0.1034 mL	0.5168 mL	1.0337 mL	2.5841 mL
	80 mM	0.0775 mL	0.3876 mL	0.7752 mL	1.9381 mL
	100 mM	0.0620 mL	0.3101 mL	0.6202 mL	1.5505 mL