4-Ethoxycarbonylmethylphenylboronic acid pinacol ester
Based on 1 Customer Validation
4-Ethoxycarbonylmethylphenylboronic acid pinacol ester is a PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity : ≥95.0%
- CAS No.: 859169-20-3
- Formula: C16H23BO4
- Molecular Weight:290.17
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Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
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All PROTAC Linkers Isoforms
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Biological Activity
Description
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E387 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 859169-20-3
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Appearance Solid
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Molecular Weight 290.17
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Formula C16H23BO4
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Color White to yellow
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SMILES
O=C(OCC)CC1=CC=C(C=C1)B2OC(C)(C)C(O2)(C)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
In Vitro:
DMSO : ≥ 100 mg/mL (344.63 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (242 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.4463 mL | 17.2313 mL | 34.4626 mL | 86.1564 mL |
| 5 mM | 0.6893 mL | 3.4463 mL | 6.8925 mL | 17.2313 mL | |
| 10 mM | 0.3446 mL | 1.7231 mL | 3.4463 mL | 8.6156 mL | |
| 15 mM | 0.2298 mL | 1.1488 mL | 2.2975 mL | 5.7438 mL | |
| 20 mM | 0.1723 mL | 0.8616 mL | 1.7231 mL | 4.3078 mL | |
| 25 mM | 0.1379 mL | 0.6893 mL | 1.3785 mL | 3.4463 mL | |
| 30 mM | 0.1149 mL | 0.5744 mL | 1.1488 mL | 2.8719 mL | |
| 40 mM | 0.0862 mL | 0.4308 mL | 0.8616 mL | 2.1539 mL | |
| 50 mM | 0.0689 mL | 0.3446 mL | 0.6893 mL | 1.7231 mL | |
| 60 mM | 0.0574 mL | 0.2872 mL | 0.5744 mL | 1.4359 mL | |
| 80 mM | 0.0431 mL | 0.2154 mL | 0.4308 mL | 1.0770 mL | |
| 100 mM | 0.0345 mL | 0.1723 mL | 0.3446 mL | 0.8616 mL |
4-Ethoxycarbonylmethylphenylboronic acid pinacol ester Related Classifications
HY-77699 Related Classifications
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