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  5. 5,7,3',4'-Tetrahydroxy-3-methoxy-8-geranylflavone

5,7,3',4'-Tetrahydroxy-3-methoxy-8-geranylflavone is a prenylflavone with anti-proliferation effect on breast cancer cells. 5,7,3',4'-Tetrahydroxy-3-methoxy-8-geranylflavone can be isolated from an ethyl acetate-soluble extract of the barks of Broussonetia papyrifera.

For research use only. We do not sell to patients.

5,7,3',4'-Tetrahydroxy-3-methoxy-8-geranylflavone

5,7,3',4'-Tetrahydroxy-3-methoxy-8-geranylflavone Chemical Structure

CAS No. : 1605304-56-0

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Description

5,7,3',4'-Tetrahydroxy-3-methoxy-8-geranylflavone is a prenylflavone with anti-proliferation effect on breast cancer cells. 5,7,3',4'-Tetrahydroxy-3-methoxy-8-geranylflavone can be isolated from an ethyl acetate-soluble extract of the barks of Broussonetia papyrifera[1].

Cellular Effect
Cell Line Type Value Description References
Hep 3B2 IC50
4.8 μM
Compound: 24
Cytotoxicity against human Hep3B cells assessed as inhibition of cell proliferation incubated for 48 hrs by MTT assay
Cytotoxicity against human Hep3B cells assessed as inhibition of cell proliferation incubated for 48 hrs by MTT assay
[PMID: 36549116]
HepG2 IC50
30.38 μM
Compound: 24
Cytotoxicity against human HepG2 cells assessed as inhibition of cell proliferation incubated for 48 hrs by MTT assay
Cytotoxicity against human HepG2 cells assessed as inhibition of cell proliferation incubated for 48 hrs by MTT assay
[PMID: 36549116]
Molecular Weight

452.50

Formula

C26H28O7

CAS No.
SMILES

O=C1C(OC)=C(C2=CC=C(O)C(O)=C2)OC3=C(C/C=C(C)/CC/C=C(C)\C)C(O)=CC(O)=C13

Structure Classification
Initial Source
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Product Name:
5,7,3',4'-Tetrahydroxy-3-methoxy-8-geranylflavone
Cat. No.:
HY-N9228
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