5,7,3',4'-Tetrahydroxy-3-methoxy-8-geranylflavone
5,7,3',4'-Tetrahydroxy-3-methoxy-8-geranylflavone is a prenylflavone with anti-proliferation effect on breast cancer cells. 5,7,3',4'-Tetrahydroxy-3-methoxy-8-geranylflavone can be isolated from an ethyl acetate-soluble extract of the barks of Broussonetia papyrifera.
For research use only. We do not sell to patients.
- CAS No.: 1605304-56-0
- Formula: C26H28O7
- Molecular Weight:452.50
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Cellular Effect
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| Hep 3B2 | IC50 |
4.8 μM
Compound: 24
|
Cytotoxicity against human Hep3B cells assessed as inhibition of cell proliferation incubated for 48 hrs by MTT assay
Cytotoxicity against human Hep3B cells assessed as inhibition of cell proliferation incubated for 48 hrs by MTT assay
|
[PMID: 36549116] |
| HepG2 | IC50 |
30.38 μM
Compound: 24
|
Cytotoxicity against human HepG2 cells assessed as inhibition of cell proliferation incubated for 48 hrs by MTT assay
Cytotoxicity against human HepG2 cells assessed as inhibition of cell proliferation incubated for 48 hrs by MTT assay
|
[PMID: 36549116] |
Chemical Information
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CAS No. 1605304-56-0
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Molecular Weight 452.50
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Formula C26H28O7
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SMILES
O=C1C(OC)=C(C2=CC=C(O)C(O)=C2)OC3=C(C/C=C(C)/CC/C=C(C)\C)C(O)=CC(O)=C13
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Structure Classification
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)